In eukaryotic initiation, one will often see the sequence ACCAUGG as a translational start sequence. This sequence is known as the ________ sequence.
The sequence ACCAUGG is known as the Kozak sequence.
The sequence ACCAUGG is the Kozak sequence, also known as the Kozak consensus sequence. It is a sequence of nucleotides that plays a critical role in the initiation of translation in eukaryotic cells. The Kozak sequence helps to position the ribosome correctly on the mRNA, so that it can begin translation at the correct start codon.The nucleus of a eukaryotic cell contains the genetic material, which is organized into chromosomes. The other membrane-bound organelles in a eukaryotic cell include mitochondria, chloroplasts (in plant cells), the endoplasmic reticulum, Golgi apparatus, and lysosomes. These organelles have specialized functions and allow eukaryotic cells to perform more complex tasks than prokaryotic cells, which lack membrane-bound organelles.
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CMSC 423 Why is it necessary to have multiple copies of the genome "shredded" in order for shotgun sequencing to be effective?
Having multiple copies of the genome shredded helps ensure that all regions of the genome are covered by the sequencing reads, increasing the accuracy and completeness of the resulting sequence assembly.
Shotgun sequencing is a method of sequencing large genomes by breaking them into small fragments and then sequencing these fragments.
In order to ensure that the sequencing is accurate and complete, multiple copies of the genome are "shredded" into fragments and sequenced independently. This is necessary for several reasons.
Firstly, the genome is a complex structure, and sequencing it accurately requires a large number of overlapping fragments to be sequenced.
By shredding the genome into many small fragments, the sequencing process can be made more efficient, as many fragments can be sequenced simultaneously.
Secondly, errors in the sequencing process can occur, and by sequencing multiple copies of the genome, the likelihood of errors can be reduced.
If errors occur in one copy of the genome, the other copies can be used to correct these errors.
Finally, some regions of the genome are difficult to sequence using traditional methods, and by sequencing multiple copies of the genome, the likelihood of these difficult regions being sequenced is increased.
In summary, shredding multiple copies of the genome is necessary for shotgun sequencing to be effective because it allows for more efficient sequencing, reduces the likelihood of errors, and increases the likelihood of difficult regions being sequenced.
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Which modification is commonly found for lysines in histones associated with constitutive heterochromatin
One of the most common modifications found for lysines in histones associated with constitutive heterochromatin is trimethylation
. Specifically, lysine 9 of histone H3 (H3K9) is frequently trimethylated in constitutive heterochromatin. This modification is often associated with transcriptional repression, and it plays a key role in the formation and maintenance of heterochromatin.
The trimethylation of lysine 9 is typically catalyzed by histone methyltransferases, such as the Suv39h enzymes in mammals. In addition to H3K9 trimethylation, other modifications can also be present in constitutive heterochromatin, such as DNA methylation and the histone modification H4K20 trimethylation.
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In the hindbrain, the cortical-spinal tracts crossover. This is called_______________. Crisscross of the neurons Decussation of the pyramids Contralateral information None of the above
In the hindbrain, the cortical-spinal tracts crossover. This is called the decussation of the pyramids. This process occurs in the medulla oblongata, which is a part of the hindbrain.
The decussation of the pyramids is a crucial event, as it enables contralateral control of the body by the cerebral cortex. This means that the left side of the brain controls the right side of the body and vice versa. The crisscrossing of neurons allows for precise and coordinated control of voluntary movements. The crossing over of these fibers in the hindbrain is responsible for contralateral information processing in the central nervous system. The cortical-spinal tracts are critical for motor function, and their decussation ensures accurate and efficient communication between the brain and the muscles.
In summary, the crossover of cortical-spinal tracts in the hindbrain is called the decussation of the pyramids. This process enables contralateral control of the body by the cerebral cortex, allowing for precise and coordinated motor function.
Therefore, the correct answer is "decussation of the pyramids".
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After fertilization, an egg has 46 chromosomes. How many chromosomes would each cell in the resulting blastocyst have
After fertilization, an egg has 46 chromosomes. The number of chromosomes in each cell in the resulting blastocyst will be 46.
After fertilization, the egg and the sperm fuse to form a single cell called a zygote. This zygote contains 46 chromosomes, half from the mother and half from the father.
As the zygote undergoes multiple rounds of cell division, it eventually develops into a blastocyst, which is a ball of cells that will eventually form the embryo and the placenta.
Each cell in the resulting blastocyst would also have 46 chromosomes. This is because during cell division, each daughter cell receives an exact copy of the genetic material (chromosomes) from the parent cell.
Therefore, as the zygote divides into more cells, each cell in the blastocyst will have the same number of chromosomes as the original zygote.
It is important to note that errors can occur during cell division, leading to changes in the number or structure of chromosomes, which can result in genetic disorders.
However, in a normal development process, each cell in the blastocyst should have 46 chromosomes.
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The thalamus __________. serves as a final relay point for sending sensory information to the cerebral cortex is the location of the melatonin-producing pineal gland regulates autonomic functions, such as heart rate and blood pressure
The thalamus serves as a final relay point for sending sensory information to the cerebral cortex.
It is a paired, egg-shaped structure located in the center of the brain, and it acts as a gateway for sensory information traveling to the cortex, which is responsible for processing and integrating sensory inputs.
The thalamus receives information from sensory organs such as the eyes, ears, and skin, and it then relays this information to the appropriate regions of the cerebral cortex for further processing.
The thalamus plays a critical role in sensory perception, attention, and consciousness.
While the pineal gland is located near the thalamus, it is not part of the thalamus itself.
The pineal gland is an endocrine gland that produces the hormone melatonin, which is involved in regulating the sleep-wake cycle.
The thalamus also plays a role in regulating autonomic functions such as heart rate and blood pressure, but it does so indirectly by relaying information to other regions of the brain that control these functions.
Overall, the thalamus is an essential structure that is involved in many aspects of sensory processing and integration, as well as attention and consciousness.
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You measure levels of Ca2 in various locations within a motor neuron and a skeletal muscle fiber when the motor neuron is not depolarized, and the muscle fiber is at rest. Where do you expect to find high levels of Ca2
When the motor neuron is not depolarized and the muscle fiber is at rest, you would not expect to find high levels of Ca2+ in either the motor neuron or the skeletal muscle fiber. This is because at rest, the concentration of Ca2+ is maintained at a low level inside both the motor neuron and the muscle fiber.
During muscle contraction, an action potential travels down the motor neuron and reaches the neuromuscular junction. This triggers the release of acetylcholine, which then binds to receptors on the skeletal muscle fiber, leading to depolarization of the muscle fiber and activation of voltage-gated Ca2+ channels on the sarcoplasmic reticulum. This results in an increase in intracellular Ca2+ concentration, which then triggers the contraction of the muscle fiber.
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The aorta, pulmonary arteries, brachiocephalic arteries, and common iliac arteries are examples of ______.
The aorta, pulmonary arteries, brachiocephalic arteries, and common iliac arteries are examples of arteries.
These arteries are classified as major arteries due to their size and the significant role they play in blood circulation. The aorta is the largest artery in the body, originating from the left ventricle of the heart and supplying oxygen-rich blood to the entire body.
The pulmonary arteries carry deoxygenated blood from the heart to the lungs for oxygenation.
The brachiocephalic arteries are major vessels responsible for supplying oxygenated blood to the head, neck, and upper limbs.
Finally, the common iliac arteries branch from the aorta and supply blood to the pelvis and lower limbs. Each of these arteries plays a crucial role in maintaining proper blood circulation and oxygen supply throughout the body.
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Why do the initial rates of glucose transport into the liposome reach a plateau as the concentration of Na increases
The initial rates of glucose transport into the liposome reach a plateau as the concentration of Na increases because the sodium ions in the solution compete with glucose molecules for transport across the liposome membrane.
As the concentration of Na increases, the number of sodium ions competing with glucose molecules for transport across the membrane also increases. This leads to a decrease in the number of glucose molecules that can cross the membrane, resulting in a plateau in the rate of glucose transport.
This process is known as the sodium ion gradient effect, and it is a physical phenomenon that occurs when charged molecules are competing for the same carrier proteins in the membrane.
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I can be converted into energy. I am also used to build, maintain and repair body tissues. I am_________. *
You are referring to protein. Protein is essential for the human body as it is used for various purposes like building and repairing tissues, producing enzymes and hormones, and also as a source of energy.
When protein is digested, it is broken down into its constituent amino acids, which can then be used to form new proteins for the body. In fact, amino acids are so important that they are considered the building blocks of life. The body needs a regular supply of protein to maintain healthy body tissues, especially muscles, which are constantly undergoing wear and tear. Thus, including protein-rich foods in your diet like meat, fish, eggs, dairy products, beans, and nuts is vital for good health.
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When a gene sequence is cloned using mRNA, which enzyme is used to seal the single-strand gaps left behind in the second strand of DNA
When a gene sequence is cloned using mRNA, the enzyme that is used to seal the single-strand gaps left behind in the second strand of DNA is DNA ligase.
DNA ligase is a critical enzyme in the process of DNA replication and repair, and it plays a crucial role in the formation of covalent phosphodiester bonds between adjacent nucleotides in a DNA strand. In the context of cloning using mRNA, DNA ligase is used to join the complementary strands of DNA that are created during the process of reverse transcription. Once the mRNA template is reverse transcribed into a complementary DNA (cDNA) strand, the resulting single-stranded cDNA is used as a template for the synthesis of a second strand of DNA.
DNA polymerase is used to extend the cDNA strand, but the resulting double-stranded DNA molecule contains single-stranded gaps that need to be sealed. DNA ligase is then used to covalently join the ends of the DNA molecule, resulting in a complete, double-stranded gene sequence that can be further manipulated and studied.
In summary, DNA ligase is the enzyme responsible for sealing single-strand gaps during gene cloning using mRNA, ensuring the integrity and stability of the cloned DNA molecule.
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The endocardium is composed of a ______ squamous epithelium, called an endothelium, and a layer of ______ connective tissue.
The endocardium is made up of a layer of subendothelial connective tissue and a simple squamous epithelium termed an endothelium.
The endocardium is the innermost layer of the heart, which lines the chambers and valves. It is composed of a simple squamous epithelium called an endothelium, which is a single layer of flat cells that form a continuous lining throughout the cardiovascular system.
The endothelium is responsible for regulating the flow of blood, preventing blood clots and inflammation, and maintaining the integrity of the blood vessels.
Underneath the endothelium, the endocardium contains a layer of subendothelial connective tissue, which is a thin layer of fibrous tissue that provides support to the endothelium. The subendothelial layer also contains smooth muscle cells, fibroblasts, and scattered macrophages, which play a role in maintaining the structural integrity of the endocardium.
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A certain gene has 5 possible alleles throughout a population. The trait controlled by this gene has ___.
A certain gene has 5 possible alleles throughout a population. The trait controlled by this gene has a wide range of variations or expressions.
The trait controlled by the gene with 5 possible alleles could have a wide range of variations or expressions. This is because each allele can encode a slightly different version of the protein that the gene produces, which can affect the function or activity of the protein in different ways.
As a result, individuals in the population who inherit different combinations of alleles may have different phenotypes or traits, ranging from subtle differences to more significant variations.
For example, if the gene in question controls eye color, individuals with different combinations of the 5 alleles could have different shades of blue, green, or brown eyes, or even unusual colors like hazel or gray.
Alternatively, if the gene controls a metabolic process, individuals with different allele combinations might have different abilities to break down certain types of foods or toxins.
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An ancient date palm seed germinated and grew into a healthy plant. What was the source of nutrients for the young sporophyte embryo during germination of the date palm seed
During the germination of a date palm seed, the source of nutrients for the young sporophyte embryo is the endosperm.
The endosperm is a specialized tissue in the seed that stores nutrients, such as starches and proteins, for the developing embryo. It provides the embryo with the energy and nutrients needed for growth until it can photosynthesize on its own.
The endosperm of a date palm seed is particularly rich in carbohydrates, including glucose and fructose, which provide the energy required for the young embryo to grow and establish its root system. Once the embryo has established itself, it can begin to photosynthesize and produce its own nutrients through photosynthesis.
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what is meant by the phrase the citrate cycle is the metabolic engine of the cell with regard to fuel work and exhaust
The phrase "the citrate cycle is the metabolic engine of the cell with regard to fuel work and exhaust" refers to the fact that the citrate cycle, also known as the Krebs cycle.
It is a crucial metabolic pathway that generates energy for the cell by breaking down fuel molecules such as glucose. This cycle takes place in the mitochondria of the cell and produces ATP, the main energy currency of the cell. The citrate cycle also produces exhaust molecules, such as carbon dioxide, which are eliminated from the cell. Overall, the citrate cycle plays a central role in cellular metabolism, serving as the primary means by which cells generate energy and eliminate waste products.
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Like many insects, some amphibians undergo ________ in their life cycle as they have distinct larval and adult stages.
Like many insects, some amphibians undergo Metamorphosis in their life cycle as they have distinct larval and adult stages.
Metamorphosis is a process by which many insects and some amphibians undergo transformation in their life cycle.
During metamorphosis, the organism goes through distinct physical changes that alter its form and physiology, leading to the development of different life stages.
In amphibians, metamorphosis involves the transformation from a water-breathing, herbivorous tadpole larva to an air-breathing, carnivorous adult with four legs and a tail. This process involves the loss of the tail, gills, and the development of lungs, limbs, and other organs necessary for life on land.
In summary, metamorphosis is a crucial process in the life cycle of many insects and some amphibians that enables them to adapt to different environments and ecological niches.
In the case of amphibians, metamorphosis leads to the development of adult forms that are adapted to life on land, enabling them to survive and thrive in diverse habitats.
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What protein, when mutated, would inhibit backward, but not outward, transport along axon microtubules
The protein that, when mutated, would inhibit backward but not outward transport along axon microtubules is called dynein.
Dynein is a motor protein that moves along microtubules and is responsible for retrograde transport, meaning it moves toward the cell body. When dynein is mutated, it can cause disruptions in retrograde transport, but not in anterograde transport, which moves away from the cell body. Specifically, mutations in dynein can result in a phenotype known as "retrograde transport defects," which can lead to the accumulation of vesicles and organelles in axons and dendrites. This can lead to various neurological disorders such as Huntington's disease, which is characterized by dynein dysfunction.
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The first vertebrates to evolve lacked jaws and had skeletons made from a strong flexible tissue called cartilage. The lamprey is a modern example of this ancient group of vertebrates known as
The lamprey is a modern example of this ancient group of vertebrates known as agnathans; the first vertebrates to evolve without jaws and with cartilaginous skeletons.
The phylum Chordata, subphylum Vertebrata, includes a group of fish with no jaws called Agnatha, which includes both living (cyclostomes) and extinct (conodonts and ostracoderms) species. All vertebrates with jaws, also referred to as gnathostomes, are related to cyclostomes among more modern creatures.
The idea that live agnathans, the cyclostomes, are monophyletic is strongly supported by recent molecular data, including rRNA and mtDNA as well as embryological data. The lampreys and the hagfish, two groups of the earliest fossil agnathans, with a combined total of roughly 120 species, are still alive today.
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Bioinformatics shows that 98% of human DNA is identical to that of chimpanzees. If human DNA contains 3.2 billion nucleotides, how many nucleotides are different between the two species
If 98% of human DNA is identical to that of chimpanzees, then the remaining 2% of DNA is different.
To calculate the number of nucleotides that are different between the two species, we need to find 2% of 3.2 billion nucleotides:
2% of 3.2 billion = 0.02 x 3.2 billion = 64 million
Therefore, there are approximately 64 million nucleotides that are different between human and chimpanzee DNA.
Step 1: Find the percentage of nucleotides that are different between the two species. Since 98% is identical, the difference is 100% - 98% = 2%.
Step 2: Calculate the number of different nucleotides by multiplying the percentage difference by the total number of human nucleotides. So, 2% of 3.2 billion nucleotides = (2/100) * 3,200,000,000.
Step 3: Calculate the result: (2/100) * 3,200,000,000 = 64,000,000 nucleotides.
So, there are 64 million nucleotides different between human and chimpanzee DNA.
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The maximum dose for oxytocin (Pitocin) is 20 milliunits per minute. Your pump is delivering 30 mls per hour. You have 20 units of oxytocin in 1000 mls of lactated ringers. How much oxytocin is presently being delivered
To calculate the current dose of oxytocin being delivered, we need to divide the total quantity of oxytocin available by the desired dose rate.
The maximum dose for oxytocin is 20 milliunits per minute, which means that we need to divide the total quantity of oxytocin by 60 minutes to get the daily dose. Therefore, the daily dose of oxytocin is 20 units / 60 minutes = 0.333 units per minute.
Since the pump is delivering 30 mls per hour, we need to convert this to units per minute to match the desired dose rate. To do this, we can divide the daily dose by the desired dose rate. Therefore, the current dose of oxytocin being delivered is 0.333 units per minute / 30 ml per hour = 0.111 units per minute.
So, there is currently 0.111 units of oxytocin being delivered per minute.
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If sperm from one species cannot survive in the reproductive tract of another species, a type of prezygotic isolating mechanism called
If sperm from one species cannot survive in the reproductive tract of another species, this is known as a prezygotic isolating mechanism. This mechanism is designed to prevent the formation of hybrid offspring, which are usually sterile or have reduced fitness. Prezygotic isolating mechanisms are important evolutionary factors that contribute to the development of new species.
There are several ways that prezygotic isolation can occur, including geographic, temporal, behavioral, and mechanical barriers. One example of mechanical isolation is when the shape or size of the reproductive structures of two species prevents successful mating. This can include differences in the shape of the male and female reproductive organs or the inability of sperm to penetrate the female reproductive tract.
In cases where sperm from one species cannot survive in the reproductive tract of another species, this is often due to differences in the chemical or physical environment of the tract. These differences may make it difficult or impossible for the sperm to reach and fertilize the egg, thereby preventing the formation of hybrid offspring.
To summarize, gametic isolation is a prezygotic isolating mechanism that occurs when sperm from one species cannot survive or function properly in the reproductive tract of another species, preventing fertilization and contributing to reproductive isolation.
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a group of organisms within a given area caoable of intervreeding and producing fertile offspring under natural conditions is called
The group of organisms within a given area capable of interbreeding and producing fertile offspring under natural conditions is called a "species".
The concept of a species is a fundamental unit in biology and is used to classify and understand the diversity of living organisms.
A species is typically defined as a group of individuals that share common characteristics and can breed with each other to produce viable and fertile offspring.
However, there can be some exceptions and complications in defining a species, such as hybridization between different species or the existence of cryptic species with subtle differences that are not immediately apparent.
Nevertheless, the concept of a species remains a fundamental building block in our understanding of the natural world.
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Conservation is Question 28 options: the most efficient use of natural resources over the long term protection of natural resources from human damage the number of species that a habitat can support smellscape none of the above
Conservation refers to a. the most efficient use of natural resources over the long term
It involves utilizing natural resources in a sustainable way, with minimum waste and damage to the environment. The focus of conservation is on long-term efficiency, ensuring that natural resources are not depleted or destroyed over time. This means that conservation measures may involve limits on resource use, recycling and reuse, and minimizing waste. The ultimate goal of conservation is to strike a balance between human needs and the preservation of natural resources.
It is not simply about protecting natural resources from human damage, but rather ensuring that they are used in a way that benefits both humans and the environment. Conservation is responsible use and management of natural resources, aimed at maintaining their availability for future generations. Therefore, the most accurate answer to the question is "a. the most efficient use of natural resources over the long term."
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A eukaryotic gene has a pre-m R N A with five exons (1, 2, 3, 4, 5). Which of the following arrangements of exons is not possible in a mature m R N A due to alternative splicing? Group of answer choices neither C nor D 1, 2, 5 1, 3, 4, 5 1, 3, 2, 4, 5
The correct answer is "1, 3, 2, 4, 5" because alternative splicing can remove or combine exons in different ways to create multiple mature mRNAs from the same pre-mRNA. However, the order of the exons cannot be rearranged during alternative splicing.
In a eukaryotic gene, alternative splicing allows for different arrangements of exons in the mature mRNA, leading to diverse protein products. However, some exon arrangements are not possible due to the necessity to maintain the reading frame and proper exon order.
Given the pre-mRNA with five exons (1, 2, 3, 4, 5), the following arrangements are not possible in a mature mRNA due to alternative splicing:
1, 3, 2, 4, 5
This arrangement disrupts the natural order of exons by placing exon 3 before exon 2. Alternative splicing can include or exclude exons, or combine them in different ways, but it cannot change the intrinsic order of the exons. So, the correct answer is 1, 3, 2, 4, 5.
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based on where its receptors are found within a given cell on its widespread effects on the body, THAT is most likely a
If its receptors are found within a given cell, it is most likely a lipid-soluble molecule.
Based on the information given, it seems that you are referring to a signaling molecule or hormone that has widespread effects on the body.
Lipid-soluble molecules, such as steroid hormones, can easily pass through the cell membrane and bind to intracellular receptors located within the cytoplasm or nucleus of the cell. Once bound, the receptor-hormone complex can directly interact with the cell's DNA, influencing gene expression and, ultimately, leading to the hormone's widespread effects on the body.
The effects of a chemical or molecule are determined by the position of receptors within a cell and by the dispersion of those receptors throughout the body. For the development of medications and treatments that can target particular receptors to have the desired effects while minimizing unfavorable side effects, it is essential to understand the mechanisms of receptor activation.
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If you wanted to determine if a lake was safe for swimming, what type of microbial count would you do and why
The simplest approach to know if a body of water is safe and the likelihood of microbial contracting a water-borne illness is minimal is to sample the water and look for the bacterium Escherichia coli (E. coli). In the intestines of humans and other mammals, E. coli is frequently discovered.
Increased risk of exposure to pathogens that might cause sickness is associated with high E. coli levels, which suggest that the water is likely to be contaminated by faeces.
Water may include a variety of pathogenic microorganisms, including viruses, bacteria, and protozoans, including Entamoeba, Giardia, and Cryptosporidium. Bacteria include Shigella, Escherichia coli, Vibrio, and Salmonella. Diatoms are one of the many microorganisms that are frequently found in pond water.
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Explain the complex body features that were developed in annelids that their flatworm-like ancestors did not have
Annelids are a diverse group of segmented worms that evolved from flatworm-like ancestors. They developed many complex body features that their ancestors did not have, including a closed circulatory system, a complete digestive system, a body cavity called a coelom, and specialized respiratory, nervous, and excretory systems.
The closed circulatory system of annelids is an improvement over the simple diffusion-based system of flatworms, which limits their size and mobility. The complete digestive system allows for more efficient food processing and waste removal, while the coelom provides a hydrostatic skeleton and allows for greater flexibility and mobility. The specialized respiratory, nervous, and excretory systems enable annelids to adapt to a wide range of environments and ecological niches.
Overall, the development of these complex body features in annelids represents a key evolutionary innovation that allowed them to thrive and diversify in a variety of habitats, from marine and freshwater environments to soil and sediments.
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Damage to the somatic motor association area of the frontal lobe would interfere with the ability to
Damage to the somatic motor association area of the frontal lobe would interfere with the ability to function.
This area plays an important role in the body's motor control, allowing for coordination and fine motor movements. It is also responsible for connecting sensory information to motor commands, which is essential for controlling voluntary movements.
Damage to this area can lead to difficulties in initiating and controlling voluntary movement, as well as impaired coordination. It can also lead to problems with planning complex tasks, as well as the ability to respond to environmental stimuli.
Furthermore, damage to this area can cause difficulty with language and the ability to plan and execute actions. It can also affect a person's capacity to think and reason logically, as well as their ability to monitor and regulate their own behavior.
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As you are making a field study of different modes of pollination of campus plants, you examine that you think utilizes wind-pollination. Which structure, if absent, would support your idea
If you examine a plant that you think utilizes wind pollination, the absence of showy, brightly colored flowers would support your idea.
In wind-pollinated plants, conspicuous, colorful, and attractive flowers are not necessary, as they do not rely on attracting pollinators (such as insects) for pollination. Instead, they rely on the wind to carry their lightweight pollen grains to other plants for fertilization.
Wind Pollination is also called Anemophily. Almost all gymnosperms are anemophilous. It is also observed in grasses, oaks, pistachios, sweet chestnuts, walnut, pine, and cereal crops like wheat, rice, maize, etc. Anemophilous pollen grains are smooth, light, and non-sticky to be transported by air currents easily.
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g In a nucleosome, the DNA is wrapped around _____.Group of answer choicespolymerase moleculeshistonesa thymine dimerribosomes
In a nucleosome, the DNA is wrapped around histones. Histones are small, positively charged proteins that act as spools around which the DNA is tightly wound.
The histone-DNA complex is called chromatin, and it plays a critical role in regulating gene expression. The nucleosome is the basic unit of chromatin structure, consisting of an octamer of histones (two each of H2A, H2B, H3, and H4) around which the DNA is wrapped approximately 1.7 times. The nucleosome structure allows for the compact packaging of DNA into the nucleus of a cell, which is essential for proper cell function. The DNA wrapped around histones in nucleosomes can also affect the accessibility of the DNA to transcription factors and RNA polymerase, which ultimately controls gene expression.
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