Which of the following events contributes to the termination of a signal generated by the binding of a ligand to a receptor tyrosine kinase? Only one answer is correct
1. Phosphatases hydrolyze key phosphorylated residues.
2. Kinases hydrolyze key phosphorylated residues.
3. Kinases phosphorylate key residues.
4. The receptor tyrosine kinase dimerizes.
5. GTPase removes a phosphoryl group from GTP.
6. Phosphatases phosphorylate key residues.

Answers

Answer 1

Answer:

1. Phosphatases hydrolyze key phosphorylated residues.

Explanation:

Receptor Tyrosine Kinases (RTKs) are high-affinity transmembrane protein receptors that bind to a wide variety of ligands (e.g., growth factors, cytokines, hormones). These receptors (RTKs) have a transmembrane domain and therefore these proteins act as membrane receptors, as well as exhibit catalytic activity. The intracellular C terminal region of RTKs contains catalytic domains responsible for both autophosphorylation and tyrosine phosphorylation of their protein substrates. Moreover, Protein Tyrosine Phosphatase (PTPs) are critical enzymes that remove phosphate groups from tyrosine residues in different substrates (including RTKs), thereby regulating key signaling pathways such as cell proliferation, cell differentiation, and cell-cell adhesion.


Related Questions

What is an office what is an office ​

Answers

Answer:

Explanation:

An office can be referred to a building or rooms or a room which is arranged and set up with furnitures and things needed for commercial use or professional work to achieve a goal.

An office is also refered to position of authority occupied by someone to perform some tasks.

Answer:

here's your answer

Explanation:

The office helps in controlling the activities of different people and department of an organisation. Through controlling it ensures that the various activities of business are performed with much accuracy. Memory Center: Office protects important information of past in a safe manner.

A penicillin reaction is a life-threatening event. In those who are allergic to penicillin, the drug acts as a __________ that binds to blood proteins, causing a strong immune response.

Answers

Answer:

A penicillin reaction is a life-threatening event. In those who are allergic to penicillin, the drug acts as a hapten that binds to blood proteins, causing a strong immune response.

Explanation:

Low molecular weight chemicals can bind to antibodies, but cannot activate B lymphocytes by themselves (they are not immunogenic). To generate specific antibodies to these small chemicals, immunologists typically bind them to macromolecules prior to immunization. In these cases, the chemical is called a hapten. Penicillin G is a typical hapten that tends to covalently bind to lysine residues both in solution and in protein-bound cells. Penicillin is a drug that behaves as a hapten, since the beta-lactam ring under physiological conditions opens and reacts with the lysine residues of proteins, forming a complex that is the main antigenic determinant of penicillin and other beta-lactams and is capable of to stimulate responses mediated by antibodies or by T cells.

do both plant cells and prokaryotic cells have 70S ribosomes ​

Answers

OK SOMEONE ALREADY ANSWERED SO I NEED DA POINTS TYSM AND ALSO ANANDI34 IT’S I HOPE IT HELPS IT’S OK THO BUT AT LEAST YOU KNOW

the flowers of the ____ bloom with sunrise and close with sunset.​

Answers

Daylillies, or hemerocallis

What kind of interaction does this image show, which acts as limiting factor on the fish?

A. mutualism
B. Parasitism
C. Commensalism
D. Predation
E. Exploitation competition

Answers

Answer:

Predation

Explanation:

The cat is the predator and the fish is its prey.

Answer:

predation

Explanation:

because

Look at the scientific names for the two organisms below:

Felis domesticus
Felis bengalensis

What can you tell about these two organisms from their scientific names?
A.
You cannot tell anything about an organism from its scientific name alone.
B.
The organisms are different subgroups of the same species.
C.
The organisms are different species but belong to the same genus.
D.
The organisms belong to the same kingdom but different phyla.

Answers

Answer:

B. The organisms are different subgroups of the same species.

QUESTION:-

Felis domesticus (Domestic CAT)

Felis bengalensis (Leopard Cat)

What can you tell about these two organisms from their scientific names?

A.

You cannot tell anything about an organism from its scientific name alone.

B.

The organisms are different subgroups of the same species.

C.

The organisms are different species but belong to the same genus.

D.

The organisms belong to the same kingdom but different phyla.

ANSWER:-

FIRST PART IS THE GENERIC PART ( genus name )

SECOND PART IS THE SPECIFIC NAME ( specific epithet )

ATQ:-

AS THE GENERIC OR GENUS NAME SAME SO THEY BELONG TO SAME GENUS

BUT DUE TO DIFFERENT SPECIFIC NAME OR SPECIFIC EPITHET WHICH SHOWS THAT THEY BELONG TO DIFFERENT SPECIES .

SO URE ANSWER IS PART C->

C. The organisms are different species but belong to the same genus.

what are the difference between DNA and RNA​

Answers

Answer:

There are two differences that distinguish DNA from RNA: (a) RNA contains the sugar ribose, while DNA contains the slightly different sugar deoxyribose (a type of ribose that lacks one oxygen atom), and (b) RNA has the nucleobase uracil while DNA contains thymine.

Why Darwin is known as father of evolution? Discuss how evidences against Darwinism led to formulation of modern evolutionary theory. Interpret its postulates in your words with relevant examples. (10 marks)

Answers

Answer:

Darwin was one of the greatest scientists who ever lived. He wrote the book 'The origin of species'. Darwin was known not only for the theory of evolution as we know it today, but also the foundation that biological sciences are based on. Darwin was very worried that people would reject his theory, so he collected a huge amount of evidence. He took evidence from the fossil record and from his own collections. He talked to animal breeders and animal collectors. He proved that the theory of evolution is based on the idea that all species are related and gradually change over time. His postulates is what gave him the title father of evolution

Postulates of evolution:-

1) Individuals within species are variable

2)Some of these variations are passed on to offspring

3)In every generation, more offspring are produced than can survive

4) The survival and reproduction of individuals are not random

The individuals who survive and go on to reproduce the most are those with the most favorable variation, and they are naturally selected.

Example:-

If an animal has to do the same task over and over again, it's body gradually changes to make the task easier. So if a deer reaches higher and higher into trees for food, day after day, it's neck will gradually stretch as it gets older.

If a deer's neck grows longer during it's lifetime, all it's babies will be born with long necks too.

Hope this helps.

Please mark me as brainliest.

What happens to urchins if the oxygen percent concentration drops too low for an extended period of time?

Answers

Answer:

Since sea urchins are picky, they are used as indicator organisms in public aquariums to determine if the system is functioning properly. This is because they are very "picky" about water quality. If the water is contaminated, the sea urchins will be the first to show signs of stress, spines laying down or falling off. Do use an aquarium filter and do clean up the day after feeding. Any metal exposed to the seawater will corrode and poison the tank. A dying sea urchin will often spawn out and rot out, causing the others in the tank to spawn and die as welll.

Explanation:

Few species could exist without oxygen. Both you and the Purple Sea Urchin would perish without oxygen. As a result, the respiratory system is necessary for most forms of life.

What is respiratory system?

Respiratory system is defined as your body's organs and other breathing-related elements, which are used to exchange oxygen and carbon dioxide during breathing. The network of organs and tissues that aids in breathing is known as the respiratory system. The respiratory system also includes the muscles that propel your lungs.

Because sea urchins are fussy, they are utilized in public aquariums as indicator species to check whether the system is working properly. This is a result of their extreme "pickiness" about water quality. Sea urchins will be the first to exhibit indications of stress, such as spines laying down or falling off, if the water is contaminated. A dying sea urchin will frequently spawn out and decay, which will cause the other sea urchins in the tank to do the same.

Thus, few species could exist without oxygen. Both you and the Purple Sea Urchin would perish without oxygen. As a result, the respiratory system is necessary for most forms of life.

To learn more about respiratory system, refer to the link below:

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First, you introduce to the parents the importance of karyotype test, by describing its ability to detect two broad categories of abnormalities in chromosomes, (1)______________________ and (2)_______________________. You provide a few examples of genetic disorders that can be caused by chromosomal abnormalities, such as (3)_________________________ and (4)_____________________. Some parents would like to know what is the main cause of these genetic disorders. Without going into too much detail, you explain to them that chromosomal abnormalities are usually caused by (5) ____________________ in meiosis I and meiosis II, when the homologous chromosomes or sister chromatids fail to separate during meiotic cell division.

Answers

Answer:

Abnormalities in Chromosomes

1. Numerical

2. Structural

3. Down Syndrome

4. Turner Syndrome

5. Disorder or Error

Explanation:

Numerical chromosome abnormalities occur due to extra or missing chromosomes.  Structural chromosome abnormalities occur due to the irregular formation or rearrangement of the chromosomal DNA, normally called translocation.  Down syndrome occurs with extra chromosomes, more than 46. Turnover syndrome results from partial or missing X chromosomes, less than 46.

there are two types of white blood cell phagocyte and lymphocytes how lymphocytes work?​

Answers

Answer:

Through receptor molecules on their surfaces, lymphocytes are able to bind antigens

Explanation:

Lymphocytes are the cells responsible for the body's ability to distinguish and react

Answer:

1. lymphocytes

2. phagocytes

3. monocytes

Explanation:

100%

vai trò, cấu tại, thuộc tính của hợp chất thứ cấp

Answers

Hợp chất thứ cấp là các chất không có chức năng trực tiếp trong các quá trình đồng hóa, hô hấp, vận chuyển, tăng cường và phát triển thực vật. Chức năng chủ yếu của các hợp chất thứ cấp là bảo vệ thực vật chống lại các tác nhân gây bệnh và động vật ăn cỏ. Nhiều chất thứ cấp có hoạt tính sinh học mạnh được dùng làm chất diệt côn trùng, nấm, dược chất. Hợp chất thứ cấp được phân làm ba nhóm chính ở thực vật: Các terpen, các hợp chất phenolic và các hợp chất chứa Nitrogen.

How old is the sun?

Answers

Our little teenage Sun is nearly 4.6 billion years old.

choose the letter of the correct answer 1. Which one of the following is NOT an organic compound? a. Methane b. Carbon dioxide d. Lactic acid C. Oil​

Answers

Answer:

B

Explanation:

5. Shawn has a hypothesis that fungicides harm bee development. Using what you now know, describe an experiment to test Shawn’s hypothesis. Be sure your response includes what data should be collected and how you would collect it.

Answers

Answer:

Yes.

Explanation:

Yes, the fungicides harm bee development by causing changes in  behavior, immune health, and reproduction etc. For verifying this hypothesis, we have to take two environments, in one environment fungicides are applied to the plants while on the other environment, there is no fungicide applied to the plants. Th result shows that the bees are affected and act abnormal where fungicides are applied as compared to those bees which are normal in behaviour and other features.

A white colony growing on mannitol salt agar tests negative for coagulase and novobiocin sensitivity. This bacterium is most likely ________________
A white colony growing on mannitol salt agar tests negative for coagulase and novobiocin sensitivity. This bacterium is most likely ________________
Streptococcus pyogenes.
Staphylococcus epidermidis.
Stpahylococcus saprophyticus.
Staphylococcus aureus.

Answers

Answer:

for the first it is Staphylococcus saprophyticus. and for the second it is Streptococcus pyogenes.

Explanation:

Answer:

1. Staphylococcus aureus.

2. Staphylococcus epidermidis.

Explanation:

A carrot would be an example of a _______ system

Answers

a carrotwould be an example of a top Root system

A carrot is an example of a Tap Root System.

why are cross section leaves placed in water immedietely are being cut​

Answers

Answer:

Although the cuticle provides important protection from excessive water loss, leaves cannot be impervious because they must also allow carbon dioxide in (to be used in photosynthesis), and oxygen out.

Explanation:

PLEASE BE QUICK! Question 7 of 35
Why do scientists use microscopes to study cells?
A. Because most cells are too dangerous to view without protection
B. Because it is quite rare to find living things that are made of cells
C. Because most cells cannot be seen without magnification
D. Because cells can be studied only after they have died
SUBMIT

Answers

Answer:

C

Explanation:

Most are too small to be seen with the naked eye. so they must be looked at with a microscope

The answer is C) Because most cells cannot be seen without magnification

Without the proper tools, the naked eye will never be able to see a cell. But when you have the correct tools, you will be able to spot them, as long if you know what you are doing. Cells are too small for the naked eye to see, just like trying to find the needle in the haystack without touching it.

Which tool is a meteorologist most likely to depend on to collect information from the
upper atmosphere?

Answers

Answer:

Anemometer is the most likely meteorologist to collect information from the high atmosphere.

Explanation:

A device to measure wind velocity and direction is an anemometer. It's also a common meteorological tool. The name comes from the Greek phrase anemos that means wind and is used to designate any meteorological wind speed instrument.

Anemometer uses

The anemometer is used for the following purposes other than to measure the wind speed:

For wind pressure measurementIn order to measure wind flowMeasuring the wind directionIt is used to assess weather conditions before testing its gadgets by drone users or RC aircraft usersUsed also by snipers and pilots of long-rangeSkydivers are used to assessing wind speed before they spring into the abyss.Used to measure airspeed in aerodynamics

Answer:

weather balloon

Explanation:

In a test cross, a pure-breeding plant is crossed with a plant suspected to be heterozygous (Aa). What is the genotype of the pure-breeding plant?

Answers

Answer:

aa

Explanation:

In genetics, a test cross is a cross performed to determine the unknown genotype of a phenotypically dominant organism. The test cross is done by crossing the unknown genotype with a homzygous recessive organism. The result of this cross tell us whether the unknown genotype is heterozygous or homzygous dominant.

According to this question, a test cross was conducted involving a pure breeding plant with a plant suspected to be heterozygous (Aa). Based on the explanation of a test cross above, the genotype of the pure-breeding plant will be "aa". Note; it must be recessive.

Question 9
What is the main difference between a prokaryote and eukaryote cell?

Answers:
The presence of a cell wall
The presence of genomic DNA
The absence of genomic DNA
Crossing over
The absence of a cell wall
Question 10

Answers

Answer:

Crossing over

Explanation:

Prokaryotic cells are cells that do not possess a membrane bound nucleus to house their genetic material e.g bacteria while eukaryotic cells possess a membrane bound nucleus that houses their genetic material e.g plants.

One important characteristics of prokaryotic cells is that they do not undergo any form of sexual reproduction, hence, cannot undergo MEIOSIS, which only occurs in sexual reproducing organisms. Prokaryotes reproduce asexually by binary fission.

Crossing over is a unique process that only occurs during meiosis. Since prokaryotic cells do not undergo meiosis, this means that crossing over is the difference between prokaryotic cells and eukaryotic cells in this question.

Which best explains why sawdust burns more quickly than a block of wood of equal mass under the same conditions?
The molecules move more quickly in the sawdust than in the block of wood.
The pressure of oxygen is greater on the sawdust.
More molecules in the sawdust can collide with oxygen molecules.
Oxygen is more concentrated near the sawdust than the block of wood.

Answers

Which best explains why, under the same circumstances, sawdust burns more fast than a wood block of equivalent mass The molecules in the sawdust move more swiftly than those in the

A thermal burn is what?

An injury to the skin or other organic tissue known as a burn is one that is primarily brought on by heat, radiation, radioactivity, electricity, friction, or contact with chemicals. When hot liquids, heated solids, or flames come in touch with the skin and other tissues, part or all of the skin's cells are destroyed (flame burns)

What various sorts of Burns are there?

This tiny burn merely penetrates the skin's surface layer (epidermis). It might hurt and make you red. second-degree burn Both the epithelium and the next layer of skin are affected by this kind of burn (dermis). It could result in skin that is swollen, red, white, or patchy. The pain may become intense and blisters may form. Scarring may result from second-degree burns that are deep.

To know more about burns visit:

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Answer:

C.More molecules in the sawdust can collide with oxygen molecules.

Explanation:

real

The ABO locus for blood typing consists of three alleles, A, B and i. An analysis the ABO blood types in the population of the Pingelap atoll of Micronesia is being planned. A Chi-Square analysis is being planned as part of the data analysis. How many degrees of freedom are there in the experiment

Answers

Answer:

1/8(12.5) if the answer is correct plz mark me as brainliest.

Describe the normal process of osteogenesis for compact and spongy bone using the three different types of bone cells and their functions

Answers

Answer:

Osteoblasts penetrate the disintegrating cartilage and replace it with spongy bone. This forms a primary ossification center. Ossification continues from this center toward the ends of the bones. After spongy bone is formed in the diaphysis, osteoclasts break down the newly formed bone to open up the medullary cavity.

Warfarin acts by inhibiting the activity of the VKORC1 protein, which helps to produce functional clotting factors. There is a variant in the VKORC1 gene that lowers the dose of warfarin required for treatment, and individuals with this variant have increased risk of bleeding when they are treated with warfarin. This variant is found 1639 base pairs upstream of the translational start site. This variant likely:______.
a. decreases the activity of the VKORC1 protein.b. increases the activity of the VKORC1 protein.c. decreases expression of the VKORC1 gene.d. increases expression of the VKORC1 gene.

Answers

Answer:

The correct answer - c. decreases expression of the VKORC1 gene.

Explanation:

Mutation of Guanine nucleotide into Adenosine is the reason for this particular type of mutation. This mutation expresses the less expression of the VKORC1 protein.

The mutation results in a decrease in the affinity of the binding site of the transcription factor which causes less expression. Since the VKORC1 protein is less in the body so Warfarin doses are decreased  

Thus, the correct answer is - decreases expression of the VKORC1 gene.

which fundamental units are involved in force do step Wise ​

Answers

Force = ma

We know, the unit that the S.I. unit of mass is Kg.

We also know that a = (v - u)/t.

We know that v = d/t and u = d/t and the S.I. unit of t(time) is s.

We know that the S.I. unit of d(displacement) is m.

So, the S.I. unit of v is m/s and the S.I. unit of u is m/s and the S.I. unit of t is s.

So, the S.I. unit of a is m/s×s or m/s²

So, the unit of force is

(unit of m) × (unit of a)

= kg × (m/s²)

= kg.m/s²

=

[tex]kg \: m \: {s}^{ - 2} [/tex]

Or more simply,

F = ma

=> F = m{(v-u)/t}

Putting units,

Newton = kg[{(m/s) - (m/s)}/s]

=> Newton = kg{(m/s)/s}

=> Newton = kg(m/s²)

=> Newton = kg.m/s²

=> Newton = kg.m.(s^-2)

The skin is protected by the action of cells that arise from bone marrow and migrate to the epidermis. Which cells serve this function?

Answers

Answer:

Langerhan's cells

Explanation:

The Langerhan's cells arise from the bone marrow and migrate to the epidermis. The Langerhan's cells are the body's first line of defense and play a significant role in antigen presentation. They need special stains to be visualized and are primarily found in the stratum spinosum. These are the mesenchymal origin obtained from CD34 positive stem cells of bone marrow and are part of the mononuclear phagocytic system.

Modelizar un ecosistema colocando los niveles tróficos y las relaciones en la red alimentaria

Answers

Answer:

Ejemplo ecosistema y su cadena trófica:  

- Ecosistema: llanura (campo de maíz)  

- Productor primario: plantas de maíz  

- Consumidor primario: Ratones

- Consumidor secundario: Aves rapaces

- Microorganismo descomponedor: bacterias  

Explanation:

En una cadena trófica o cadena alimentaria de un ecosistema, cada nivel obtiene la energía necesaria para sustentar la vida a partir del nivel inmediatamente anterior, mientras que los productores primarios son aquellos organismos que hacen ingresar la energía al ecosistema. Por otra parte, los descomponedores son organismos que se alimentan de los restos de animales y plantas, mediante su descomposición, obteniendo de ellos energía y materia hasta transformarlos en materia inorgánica. En el ejemplo arriba citado, las plantas de maíz representan los productores primarios los cuales producen energía y materia orgánica requerida para sustentar el ecosistema mediante el proceso de fotosíntesis. En segundo lugar, los ratones, como así también otros organismos herbívoros, representan los consumidores primarios los cuales conforman el segundo nivel trófico de la cadena alimentaria. En tercer lugar, los animales carnívoros que se alimentan de consumidores primarios (como por ejemplo, aves rapaces) representan el tercer nivel trófico, y así sucesivamente niveles superiores en el caso que existan depredadores mayores en el ecosistema. Finalmente, bacterias y otros organismos (por ejemplo, hongos, lombrices, algunos insectos, etc) representan los descomponedores los cuales se alimentan de restos orgánicos en descomposición, transformándolos de este modo en compuestos inorgánicos que ingresan nuevamente al ecosistema.

Pls help thank you

A group of geologists is about to start excavating a new area for fossils. The area they are working in is the side of a cliff. Describe two pieces of information they will most likely be able to discover about the fossils they will find.

Answers

Answer:

Forms of fossils and there arrangement with layer of rock.

Explanation:

The seashore is a significant place for the depositional work of waves and it's also one of the significant places for the erosion and weathering of rocks.  The presence of sedimentary rocks along the cliffs are essential for the discovery of fossils of plants and animals. Fossils of shells and other creatures that were of marine origin are mostly discovered near excavation sites. Fossil helps to prove the age of rocks and strata.
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Which of these is an example of technology?an idea for a storythe first wheel ever builtan engineer Sensory adaptation /habitation,color, blindness,deafness,our senses,perceptual illusions,reflect and summarize in your own words why knowledge of these area would be important in the workplace how much water consumed by Aguilar family as shown in the meter reading Journalizing credit sales, note receivable transactions, and accruing interest. Endurance Running Shoes reports the following: 2018May 6 Recorded credit sales of . Ignore Cost of Goods Sold. Jul. 1 Loaned $18,000 to Jerry Paul, an executive with the company, on a one-year, 7% note.Dec. 31 Accrued interest revenue on the Paul note. 2019 Jul. 1 Collected the maturity value of the Paul note. Journalize all entries required for Endurance Running Shoes. I need help, and I cant figure it out What is the coefficient of x^8 in the expansion of (x+4)^12 ? Can someone help me with this question and show me how to solve them pleases? Question 14 (5 points)Which of the following is equivalent to cos (23)?cos (90)sin (67)sin (23)cos (67) Lesson: Hierarchical Taxonomic System of ClassificationMELCS: 1. Explain the concept of a species.2. Classify organisms using the hierarchical taxonomic system.1. Directions: Using the Linnaean system of classification, describe these living things.CATEGORYHumanDomainKingdomPhylumClassOrderFamilyGenusSpeciesW How do Americans influence the government? Characteristics of social consciousness in Vietnam Integrate with respect to x-2/3((2-5x)^3) Leahy Corp. sells $300,000 of bonds to private investors. The bonds are due in five years, have a 6% coupon rate, and interest is paid semiannually. The bonds were sold to yield 4%. Group of answer choices The bonds were sold at a discount, with annual interest expenses more than $18,000 The bonds were sold at a discount, with annual interest expenses less than $18,000 The bonds were sold at a premium, with annual interest expenses more than $18,000 The bonds were sold at a premium, with annual interest expenses less than $18,000 The bonds were sold at par, with annual interest expenses equal to $18,000 What is the minimum angular spread (in rad) of a 534 nm wavelength manganese vapor laser beam that is originally 1.19 mm in diameter Suppose an enzyme and its substrate obey the lock and key model of enzyme catalysis. Which of the following would be true of the enzyme? a. only one substrate could be converted to product by the enzyme b. the active site of the enzyme must be rigid c. the entire enzyme must be rigid d. the active site of the enzyme must be flexible e. the enzyme could bind different substrates if the substrates shared a common motif somewhere in their structures Mike wants to find out whether campers prefer cotton or nylon sleeping bags. He asks a group of female campers to try both nylon and cotton sleeping bags. The sleeping bags were rated for softness and warmth. Mike intends to generalize the findings to apply to all campers. What is the confounding variable in Mike's experiment Help me find the mistake in this sentence The branch of life sciences which involves the structure and function of the brain and nervous system, including neurons, nerves, and nervous tissue is called Which Group is in the second column of the periodic table?O A. Noble gasesO B. Alkaline earth metalsO C. Alkali metalsO D. Halogens If interest is 8% and it is compounded semiannually, and after one year, the total value is $10,816, what was the original investment? Which of the following statement is true? a) Consideration need not be any particular value. b) Consideration should accord the deed of the person who is at the position to do it. c) Consideration may proceed the promise that the promise or promisor pass to each other. d) An act done at the desire of a third party is equal to consideration.