The pre-mRNA produced after transcription of the DNA contains both introns and exons. Introns are the non-coding sequences, i.e., they do not code for amino acids, while the exons code for the amino acids.
The introns are removed from the pre-mRNA with the help of a process known as RNA splicing. It is a complex process involving the spliceosome machinery. The spliceosome is a complex consisting of the snRNA's (small nuclear RNA's) - U1, U2, U3, U4, U5 - where each snRNA is complexed with about seven protein subunits from snRNP's (small nuclear ribonucleoprotein).
The order in which RNA splicing occurs is:
a. BBP (branch-point binding protein) and U2AF bind to A in the branch point site in the intron, while the U1 snRNP binds to 5’ splice site.
- The U1 snRNP has a complementary base pair to the 5' splice site and binds with it. On the other hand, the BBP and U2AF (U2 assisting factor) recognize and bind to the branch point.
b. The U2 snRNP binds the branch point site and the U4/U6 and U5 snRNP’s bind to the 5’ splice site.
- The U2 snRNP displaces the BBP and u2AF from the branch point, and itself forms a complementary base pair with the branch point. The entry of U4/U6 and U5 takes place. First, U4/U6 will bind strongly to the pre-mRNA, but rearrangements occur which causes U6 to displace U1 from the 5' splice site.
c. A conserved adenine in the branch point site attacks the 5’ splice site, cutting the RNA at the 5’ splice site.
d. The 5’ end of the intron binds the branch point adenine, forming a lariat.
- A covalent bond is formed.
e. The 3’ end of the first exon interacts with the 3’ splice site, forming a new bond in the sugar-phosphate backbone.
- The 3'OH end of the first exon interacts and forms a new sugar-phosphate bond, joining them together.
f. The lariat is released and degraded.
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Full Question: Part 1 (1 point) Place the following steps of RNA splicing in the correct order from first step to last. Question List (6 items) (Drag and drop into the appropriate area) RNA Splicing First step A conserved adenine in the branch-point site attacks the splice site, cutting the RNA at the 'splice site 1 Thelorlat is released and degraded 2. BP and U2AF bind to the Ain the branch-point site in the intron while the U1 sRNP binds the 5' splice site O OF 12 QUESTIONS COMPLETED < 06/12 > Tch 05/24/20 The other formiranew hond in the 3 The 5 and of the tranbinds the branch-point forming at 4 The UnNP binds the branch point site and the U/US and US bind to 5 OF 12 QUESTIONS COMPLETED < 06/12 > Type here to search o RE
Research indicates that Albuterol, a drug used to relax bronchial muscles, improving airflow and thus offering relief from asthma, consists of only one enantiomer, the R-form. Why is it important for this drug to consist of only one enantiomeric form, rather than a mixture of enantiomers?
A. Different enantiomers may have different or opposite physiological effects.
B. It is impossible to synthesize mixture of enantiomers
C. It is much less expensive to synthesize one enantiomer at a time
D. Only the R-form of Albuterol has been studied; until more information is available, physicians prefer to use the pure R-form.
The correct answer is A. Different enantiomers may have different or opposite physiological effects.
Enantiomers are mirror images of each other and have the same physical and chemical properties, but they can have different physiological effects on the body.
In the case of Albuterol, only the R-form has the desired effect of relaxing the bronchial muscles and improving airflow. The other enantiomer, the S-form, may have no effect or even an opposite effect. Therefore, it is important for this drug to consist of only one enantiomeric form, the R-form, to ensure its effectiveness in treating asthma.
It is important for Albuterol to consist of only one enantiomeric form, rather than a mixture of enantiomers, for several reasons. Firstly, different enantiomers may have different or opposite physiological effects.
For example, the S-form of Albuterol has been shown to have weaker bronchodilator effects and can also cause side effects such as tremors and anxiety. This means that if Albuterol contained both the R- and S-forms, it could potentially be less effective and have more side effects.
Options B, C, and D are incorrect because it is possible to synthesize a mixture of enantiomers, the cost of synthesis is not the main concern, and the R-form is not the only form that has been studied.
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Which of the following is the principal organ for digestion and absorption of food in our body?A) Large intestineB) LiverC) PacreasD) Small intestine
The main organ in our body for food digestion and absorption is the small intestine.
Miniscule intestine
The ongoing breakdown process is largely its fault. The majority of nutrient absorption into the bloodstream occurs in the jejunum and ileum, two lower intestine regions.
Following passage through the small intestine, the contents change from a semi-solid to a liquid state. The change in consistency is caused by bile, enzymes, water, and mucus. The liquid leftover from the digestion of the food moves to the large intestine after the nutrients have been absorbed and the small intestine has been cleared of it (colon).
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what is the function of the axon terminal
plasmodesmata enable metabolic communication between?
Plasmodesmata are specialized structures that enable metabolic communication between adjacent plant cells. They are narrow channels that traverse the cell walls between plant cells.
What is the importance of plasmodesmata?Plasmodesmata play an important role in coordinating metabolic processes between plant cells. They enable the movement of nutrients, signalling molecules, and other essential compounds between cells, allowing for the efficient sharing of resources and the rapid transmission of signals throughout the plant.
What are the structures that help in metabolic communication in humans?In humans, several structures help in metabolic communication between cells like Gap junctions, Desmosomes, Tight junctions, Hemidesmosomes and Tunneling nanotubes.
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which of these reagents binds to protein to create a color change that you can measure?
The Bradford reagent is often used to bind to proteins and produce a colour change that can be measured.
The Bradford reagent is a methanol and water solution containing Coomassie Brilliant Blue dye and phosphoric acid. The dye in the reagent binds to protein amino acid residues, namely arginine, lysine, and histidine, producing a shift in the dye's absorption spectrum and a change in colour from brown to blue. The intensity of the blue hue is related to the protein content in the sample. As a result, the quantity of protein in the sample may be determined by measuring the absorbance of the blue colour with a spectrophotometer.
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what type of stress results from rocks being pushed together?
A shear stress. B compression. C strain.
The type of stress that results from rocks being pushed together is compression. Here option B is the correct answer.
Compression is a type of stress that occurs when rocks are squeezed or pressed together by a force acting in opposite directions. This type of stress is commonly associated with convergent plate boundaries, where two plates move toward each other and collide, resulting in the compression and deformation of the rocks along the boundary.
During compression, rocks may be folded, faulted, or uplifted, depending on the orientation of the force and the physical properties of the rocks. The amount of compression and resulting deformation depends on the magnitude and direction of the force, as well as the type and strength of the rocks.
Another type of stress that can occur in rocks is shear stress, which results from forces acting parallel to each other in opposite directions, such as in a transform plate boundary. Strain refers to the deformation or change in shape that occurs as a result of stress.
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Left ventricular contraction propels blood through which valve?A. Aortic valveB. Pulmonary valveC. Left atrioventricular (bicuspid) valveD. Right atrioventricular (mitral) valve
Blood that is rich in oxygen is transported from your lungs to your left atrium via broad veins known as pulmonary veins. Your mitral valve opens, allowing blood to move from your left atrium to your left ventricle.
The left ventricle pumps blood through where?The largest artery in the body, the aorta, receives blood that passes through the aortic valve after the left ventricle contracts, closing the mitral valve and opening it. Except for the lungs, this blood transports oxygen throughout the entire body.
What is the term for left ventricle contraction?It consists of two phases: a systole, during which the heart muscle contracts vigorously and pumps blood, and a diastole, during which the heart muscle relaxes and replenishes with blood.
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Evidence that some species have changed over time can be found in ?
O The fossil record
O a single individual fossil
O rocks
Oliving fossils
Answer: The Fossil Record
Explanation:
the process by which modern organisms have descended from
The process by which modern organisms have descended from ancient organisms
What three things influence evolution?Natural selection, genetic drift, and gene flow are the mechanisms that change allele frequencies over time. If one or more of these conditions are met and evolution occurs, the Hardy-Weinberg presumptions are broken by a population.
British biologist Charles Darwin travelled the world on the HMS Beagle. He watched, accumulated information, and developed a hypothesis on how life originates from other living things and develops over time.
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the two main factors that determine where organisms live are
The two main factors that determine where organisms live are "biotic" and "abiotic" factors.
Biotic factors include living organisms, such as other plants and animals, which can affect an organism's survival by competing for resources, predation, or providing mutualistic benefits.
Abiotic factors include nonliving factors, such as temperature, water availability, soil quality, and other physical and chemical characteristics of the environment, which can also impact an organism's ability to survive and reproduce.
Together, biotic and abiotic factors determine an organism's "habitat," which is the specific environment in which it can survive and thrive. Different organisms have different adaptations that enable them to survive in particular habitats and niches, which is the role they play in the ecosystem. Understanding the biotic and abiotic factors that shape an organism's habitat and niche is critical to understanding their ecology and interactions within the larger ecosystem.
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What objective should be in place when the microscope is stored?
A. 100x (oil objective / lens)
B. 40x (high dry / power objective )
C. 20x (low power objective)
D. 4x (scanning objective)
D. 4x (scanning objective). Prior to putting the microscope away, make sure the stage is in its lowest position and that the 4X objective is always above it.
How should a microscope's stage or objectives be set up when it is being stored?Keep the 10X (power loss) objective in place when storing microscopes.As little space as possible should exist between the stage as well as the objective lens, raise the stage the all way up.DO NOT round the microscope with the rope.Place the rope folded and between the stage and the arm instead.
Which objective lens ought to remain in place?Always place your microscope's scanning or sharpest objective in its storage position.This is equivalent to a compound microscope's 4X objective lens.
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What are the ASL classifiers?
American Sign Language (ASL) classifiers are handshapes that represent nouns and verbs and are used to provide more detail and specificity to signs.
They are an important part of ASL grammar and syntax and can convey information about size, shape, movement, location, and orientation. There are various types of classifiers in ASL, including descriptive classifiers, locative classifiers, and instrument classifiers, among others.
Each type of classifier is associated with a specific type of noun or verb and has a unique handshape and movement pattern. For example, a classifier used to describe the shape of an object might use a handshape that resembles the object, such as a flattened "O" shape to describe a round or flat object.
A locative classifier might use a handshape to indicate the location of an object in space, such as a "C" shape to represent a person or animal standing or walking. Classifiers are an important aspect of ASL proficiency and are taught and practiced extensively in ASL classes and programs.
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what level of protein structure describes the spatial location of every atom in a protein?
Polypeptide chain's amino acid level of protein is the main structure which describes the spatial location for every atom present in the protein.
Tertiary structure is the three-dimensional arrangement of an entire polypeptide chain; and quaternary structure is the arrangement of a protein's quaternary structure. The spatial organization of a protein affects its biological function; in other words, the primary structure of a protein must bend to produce a secondary structure, which is then packaged in a tertiary structure.
The quaternary structure can occasionally be formed by joining the tertiary structures of numerous proteins or subunits. The entire three-dimensional structure of a polypeptide chain, or the relationship in space between each amino acid residue, is referred to as the tertiary structure.
The primary structure of a protein is its polypeptide chain's amino acid composition; secondary structure is the local spatial arrangement of a polypeptide's backbone (main chain) atoms.
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Which two organs of a plant interact to cause seedlings to grow upward?
A. Seeds and roots
B. Stems and leaves
C. Leaves and seeds
D. Roots and stems
ts and
The two organs of a plant that interact to cause seedlings to grow upward are known as Seeds and roots. Thus, the correct option for this question is A.
What is a seedling?A seedling may be characterized as a young sporophyte that significantly develops out of a plant embryo from a seed. The development of the seedling initiates with the germination of seeds.
A typical young seedling consists of three main parts: the radicle (embryonic root), the hypocotyl (embryonic shoot), and the cotyledons (seed leaves).
Vascular plants have two distinct organ systems: a shoot system, and a root system. The shoot system consists of stems, leaves, and the reproductive parts of the plant (flowers and fruits).
Therefore, the two organs of a plant that interact to cause seedlings to grow upward are known as Seeds and roots. Thus, the correct option for this question is A.
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Answer:roots and stems!
Explanation: I got it right
How did Hershey and Chase prove that DNA is the genetic material?
Bacteriophages (viruses that infect bacteria) were important to Hershey and Chase's experiment, which demonstrated that DNA is the genetic material.
Hershey and Chase demonstrated that when bacteriophages, which are made up of DNA and protein, infect bacteria, the DNA enters but the majority of the protein does not. Hershey and Chase, as well as other findings, all contributed to the conclusion that DNA is the hereditary material. The Hershey-Chase studies, undertaken in 1952 by Alfred Hershey and Martha Chase, helped to prove that DNA represents genetic material.
While biologists had known about DNA since 1869, many scientists still concluded that proteins contained the information for heredity at the time since DNA looked to be an inert molecule and, because it is situated in the nucleus, its purpose was thought to be phosphate storage.
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oocytes complete meiosis ii before they are fertilized.
The optional oocyte remains halted in meiosis II until a sperm cell prepares it. This starts the egg to finish meiosis II. During meiosis II, the copied chromosomes are parted into a polar body and an adept ovum.
As of now, the haploid cores of the egg and sperm can break to shape the zygote.
After ovulation, the oocyte is captured in the metaphase of meiosis II until preparation. At preparation, the optional oocyte finishes meiosis II to frame an experienced oocyte (23,1N) and a second polar body.
Meiosis II happens following the sperm enters the auxiliary oocyte. The oocyte is obstructed in the metaphase of meiosis II after ovulation preceding preparation. Meiosis is a cycle that happens in the ovaries of females during the improvement of mature gametes or eggs.
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according to the phylogenetic tree in the accompanying figure, g. intestinalis constitutes a ________ group.a. Giardia murisb. Giardia intestinalis Subgroups A-Dc. Giardia microti
According to the phylogenetic tree in the accompanying figure, g. intestinalis constitutes a (b) Giardia intestinalis Subgroups A-D group.
Based on the genomic study, the phylogenetic tree in the accompanying image depicts the relationships that have developed over time among the many Giardia species. The various branches on the tree stand in for various subgroups of the genus Giardia.
Giardia intestinalis is a group in the tree that contains the subgroups (A–D), and G. intestinalis is a member of this group. This indicates that G. intestinalis is closely linked to other species within the Giardia intestinalis group and that these species and G. intestinalis share a more recent common ancestor than do other species within the genus Giardia.
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If a population was void of predators, and the organisms were able to satisfy their needs, the population would experience
If a population was void of predators, and the organisms were able to satisfy their needs, the population would experience exponential growth, option A.
What is exponential growth?Exponential growth is a type of population growth pattern in which the number of individuals in a population increases at an accelerating rate, leading to a J-shaped curve on a graph over time. In this type of growth, the rate of increase is proportional to the current population size, meaning that as the population gets larger, the rate of growth also gets larger.
This can occur in populations with unlimited resources and no limiting factors, such as predators or competition, but it is not sustainable in the long term as resources eventually become limited.
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What factors affect the activity of the autonomic reflex of the heart center?
Alcohol consumption, smoking, and physical activity may all have an impact on cardiovascular disease via altering ANS activity.
Autonomic reflexes have an impact on what?The ANS influences various physiological processes, including urine, salivation, sweating, pupillary dilation, and sexual desire. Although many ANS actions can coexist with some level of conscious control, the majority of autonomic functions are involuntary.
How does heart rate impact autonomic reflexes?The two branches of the autonomic (involuntary) nervous system regulate heart rate. The parasympathetic nervous system and the sympathetic nervous system (SNS and PNS) (PNS). To increase heart rate, the sympathetic nervous system (SNS) produces the catecholamines epinephrine and norepinephrine.
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most bacterial cells are encased by a strong cell wall composed of which is a carbohydrate matrix cross-linked by polypeptides. t/f
Most bacterial cells are encased by a strong cell wall composed of peptidoglycan or murein which is a carbohydrate matrix cross-linked by polypeptides.
The statement is false.
The distinct big macromolecule known as peptidoglycan, also known as murein, is a polysaccharide made up of sugars and amino acids that forms a layer that resembles a mesh outside the plasma membrane and makes up the hard cell wall (murein saccules) that is characteristic of most bacteria (domain Bacteria ). Alternating residues of N-acetylglucosamine (NAG) and N-acetylmuramic acid make up the sugar component (NAM). An oligopeptide chain with three to five amino acids is joined to the N-acetylmuramic acid.
A layer that resembles a 3D mesh can be created by cross-linking one peptide chain to another peptide chain on another strand. The bacterial cell wall's peptidoglycan plays a structural role by providing structural support and balancing the cytoplasm's osmotic pressure.
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How do you find the point of maximal impulse?
The point of maximal impulse, also known as the PMI, is the point on the chest wall where the impulse of the heart is felt the strongest. To find the PMI, you can follow these steps:
1. Have the patient lie down in a comfortable position.
2. Place your hand on the patient's chest wall, with your fingers spread apart.
3. Feel for the point where the impulse of the heart is strongest. This is typically located in the fifth intercostal space, just to the left of the sternum.
4. Mark the point of maximal impulse with a pen or marker.
It is important to note that the PMI may be displaced in certain conditions, such as in cases of cardiac enlargement or in patients with lung disease. In these cases, the PMI may be located in a different area of the chest wall.
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Which of the statements is true regarding glycine? R=H Select all that apply O Glycine is a polar amino acid. O Glycine is a large amino acid. OGlycine is an asymmetric amino acid. O Glycine increases the flexibility of the peptide backbone. O The side chain is small so it tucks in O Glycine is kinky (causes a bend in protein backbone) because the side chain binds to the central carbon AND the amino ogroup. O Glycine is special because it contains a -SH group important in protein folding.
The correct statement about glycine is: Glycine increases the flexibility of the peptide backbone.
Glycine is a non-polar, symmetric, non-essential and proteinogenic amino acid. The glycine has 2 hydrogen groups which makes it a symmetric molecule. The living body can make glycine on its own and hence it is non-essential.
Peptide is the structure made of several amino acids joined together by peptide bond. The size of a peptide is smaller that a protein. The backbone of a peptide molecule is made up of the nitrogen, ɑ carbon, and the carboxyl carbon. The side chains of amino acid do not take part in backbone formation.
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T/F? Human body cells with 46 total chromosomes are called gametes and are haploid.
True. Gametes, which have 46 chromosomes overall, are haploid human body cells.
A pair of nonhomologous chromosomes and two sets of 22 homologous pairs make up the 46 chromosomes found in human somatic cells. The 2n, as well as diploid, state, is this. One complete pair of chromosomes, or 23 chromosomes, is present in each human gamete. The n, as well as haploid, phase is this. Two complete pair of chromosomes are present in a diploid cell. The majority of human cells are diploid, with 23 chromosomal pairs totaling 46 chromosomes. Every human cell in the body has 23 pairs of these chromosomes, making our diploid number 46 and our 'haploid' number 23.
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T/F? At rest, veins contain the largest percentage of blood in the body.
The given statement "At rest, veins contain the largest percentage of blood in the body." is true because the greatest volume of blood is basically found in these vessels due to their lumen.
As the blood happens to flow into the smaller sized arteries as well as the arterioles, the pulsatility is seen to get declined. The greatest amount of blood volume is found in the venous vasculature which contains the veins and the vessels. They contains about 60-80% of the total blood volume at rest and this because of their larger lumen.
For this reason, veins are also known as the capacitance vessels. Arteries in our body contain about 12% of the blood volume, the veins contain about 60% of the total blood volume and capillaries happen to contain 7% blood volume.
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decreasing the angle between two bones by bending a limb at a joint is?
Decreasing the angle between two bones by bending a limb at a joint is called flexion.
Flexion is a movement that occurs at a joint and results in a decrease in the angle between two bones. This movement typically occurs in the sagittal plane, which divides the body into left and right halves, and is commonly associated with bending or folding of body parts.
For example, flexion of the elbow joint involves bending the forearm towards the upper arm, whereas flexion of the knee joint involves bringing the lower leg towards the thigh.
Flexion is one of several types of joint movements, including extension (opposite of flexion), abduction, adduction, rotation, and circumduction, that allow the body to perform a wide range of movements and activities.
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what approach should you take If you were to analyze a newly discovered unicellular organism to determine whether it should be classified as a prokaryote or a eukaryote?
Check to see if the organism utilizes cytoskeletal proteins to do is provide cell structure.
Since prokaryotic cells lack a membrane-bound nucleus, eukaryotic cells are the main distinction between the two types of creatures. Eukaryotes store its genetic material in their nuclei. Prokaryotic cells lack membrane-bound organelles, whereas eukaryotic cells do (including the nucleus and mitochondria). DNA in prokaryotic cells is present in the cytoplasm, whereas it can be found inside the nucleus of eukaryotic cells. Compared to prokaryotic cells, eukaryotic cells are often larger and more complex. The apparent lack of a nucleus encircled by a nuclear membrane distinguishes the two types. The nucleus is not membrane-bound in prokaryotic cells. Compared to eukaryotic cells, they are often smaller and less complex.
(Suppose you're analyzing a newly discovered unicellular organism to determine whether it should be classified as a prokaryote or eukaryote. How should you approach it?)
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what are white blood cells called, which have specific granules in their cytosol that are clearly visible when viewed with a microscope
One group of white blood cells that have specific granules in their cytosol that are visible when viewed with a microscope are called granulocytes.
Granulocytes are so named because they contain granules, or small packets of enzymes and other substances, in their cytoplasm. These granules are important for the function of the granulocytes, as they contain enzymes that can break down pathogens and other foreign substances. Granulocytes are further classified based on the type of granules they contain and their morphology, or shape.
There are three main types of granulocytes: neutrophils, eosinophils, and basophils. Neutrophils are the most common type of granulocyte and are important for fighting bacterial infections. Eosinophils are involved in allergic reactions and parasitic infections, while basophils play a role in the body's response to inflammation and allergic reactions. When viewed under a microscope, the granules in these cells can be clearly seen, and their specific staining properties can be used to identify and differentiate the different types of granulocytes.
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Fill the blank! the region of a bacterial cell that contains the genetic material is called the __________.
The region of a bacterial cell that contains the genetic material is called the nucleoid.
What is bacterial cell?A bacterial cell is a type of cell that is found in bacteria, which are single-celled microorganisms that can be found in a wide variety of environments, from soil and water to living organisms. Bacterial cells are prokaryotic, which means they lack a distinct nucleus and other membrane-bound organelles. Bacterial cells are generally smaller and simpler in structure than eukaryotic cells, which are found in animals, plants, and fungi. They typically have a cell membrane that encloses the cytoplasm, which contains the genetic material (DNA) in the form of a single circular chromosome, as well as various other organelles such as ribosomes for protein synthesis, and sometimes flagella or pili for movement.
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what occurs in natural selection? (write full sentences)
Answer:
Natural selection is the process by which certain traits become more common in a population due to the survival and reproduction of individuals with advantageous traits in response to environmental pressures. This can lead to the evolution of new species over many generations. Conversely, individuals with less advantageous traits are less likely to survive and reproduce, resulting in a decrease in the frequency of those traits in the population. Natural selection is a crucial mechanism of evolution that drives changes in the traits and characteristics of populations over time.
Answer: genetic mutations that are beneficial to an individual's survival are passed on through reproduction.
Explanation: I hope this helps
how many lymphatic trunks are normally found in the body?
The lumbar, bronchomediastinal, subclavian, and jugular trunks are the four pairings. Additionally, one intestinal lymph trunk that is not paired drains lymph from the majority of the digestive system's organs.
Any substantial lymphatic vessel that develops from the union of numerous efferent lymph vessels is referred to as a lymphatic trunk. In addition to one unpaired trunk, there are four pairs of lymph trunks, each with a right and left half.
The final component of the lymphatic system, the lymph ducts are served by lymphatic trunks, which subsequently discharge lymph fluid into them. The lymph trunks send their contents to two lymph ducts. The largest lymphatic vessels have three layers, resembling great veins, and are composed of them.
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