PLEASE HELP ME!!!! This figure shows two alleles for the beta-globin gene. The A allele is the most common allele. The S allele is responsible for Sickle Cell Disease. The R group glutamic acid is negatively charged, while the R group of valine is hydrophobic. What molecular change, ultimately resulting in the sickle cell phenotype, occurs when valine in substituted in place of glutamic acid at position 6 in the β subunit of hemoglobin?

PLEASE HELP ME!!!! This Figure Shows Two Alleles For The Beta-globin Gene. The A Allele Is The Most Common
PLEASE HELP ME!!!! This Figure Shows Two Alleles For The Beta-globin Gene. The A Allele Is The Most Common

Answers

Answer 1

Answer:

The correct answer is option B. The tertiary structure of the beta subunit changes, exposing a hydrophobic cleft which allows hemoglobin to form long chains in RBC.

Explanation:

As it is clearly mention as there is point mutation that leads to single nucleotide change which results in to valine instead of glutamate. Valine is hydrophobic in nature not like glutamate. Valine aggregate and makes a rigid structure of molecules.

Due to this rigid molecule of valine aggregates, RBCs form a crescent or sickle like shape due to the higher viscosity and low solubility of Mutated hemoglobin in deoxy condition. It leads to formation of polymer that blocks the vessels.

Thus, the correct answer is option B.


Related Questions

what is the need for classification ​

Answers

Answer:

The correct answer is to: characterized them and study them on the based of shared characteristics, similarities and phylogeny.

Explanation:

Arranging different type of organisms on the basis of their shared characteristics such as physical similarities, anatomical characters, phylogeny, habitat they share and many more, in order to study them easily known as classification.

Classification helps understanding the diversity of living organisms with the help of their features, similarities and differences. Aim of the classifying organisms is to, identification of organisms, to establishing the evolutionary relation among different type of organisms and studying the phylogeny.

The graph shows the change in the number of Bt and HT crops grown in the United States from 1996 to 2005 BT crops are resistant to being eaten by insects HT crops are resistant to herbicide’s based on the information in the graph which is most likely true about farming in 2005

Answers

Answer:

C. Fewer crops were eaten by pests.

Explanation:

Answer:

Yes, the answer is C

Explanation:

got it right in edg 2020

hope this is of help :)

Explain briefly what the El Niño Northern Oscillation (ENSO) is and how it would affect the following locations: Piura, Peru; Port Moresby, Papua New Guinea; Gainesville, FL, USA. Be detailed and scientific – give reasons and explain your answer for each location.

Answers

Answer and Explanation:

The ENSO phenomenon is the result of a complex system of climatic oscillations between the ocean and the atmosphere. It is considered to be dominant in the global climate system. This phenomenon is associated with important perturbations in the normal pluvial regimens in the tropics, resulting in dry seasons in areas where usually rains, and rainy seasons in areas that are usually desertic.

Under normal conditions, warm water and air masses move westward, which makes it possible for cold water to ascend in a process known as upwelling. This upwelling occurs in South America´s coasts, providing nutrients from the bottom to the animals, especially fishes -which favors fisheries activities-. Humidity goes straight to the west precipitating in Indochina and North Australia, among other places.  

Under El Niño conditions, a tropical stream, which is normally small, acquires strength while the opposite streams debilitate. This avoids warm water to go eastward, remaining in South America´s coasts, which produces unusual precipitations in areas such as Chile´s coasts -followed by floral bloom in Atacama desert-, and fewer precipitations in Eastsouth Asia and North Australia. Upwelling does not occur on the coasts of South America, so there is a fishery crisis because nutrients from the bottom do no ascend and fish populations remain equal or smaller. In areas such as Piura, Perú, during el Niño events, temperatures use to rise in the coastal areas and precipitation also increase.  Nueva Guinea, on the other hand, seems to one of the most affected areas in Eastsouth Asia under the influence of El Niño event. Rainfall during ENSO drops below the average, affecting crops and livestock.    

ENSO also provokes changes in general extratropical circulation contributing to some anomalous situation in the northern hemisphere weather during winter, including severe precipitations and cooler temperatures in the southeast USA, north of Mexico, Gulf of Mexico, Strait of Florida and western Cuba.  

Cola has a pH of 3.5. This means that it has an excess of ________ ions and would be called a(n) ________. Group of answer choices H+; neutral solution H+; base OH-; base H+; acid OH-; acid

Answers

Answer:

Has an excess of H+ ions and would be called acid


What type of weak bond occurs when atoms and molecules are temporarily attracted to each other by virtue of their proximity and
charge

Answers

Van de waals are considered the weakest bonds between any two molecules

The weak bonds that occur when atoms and molecules are temporarily attracted to each other by virtue of their proximity and charge are Vander Waal forces.

What are Vander Waal forces?

Van der Waals forces are weak forces that keep electrically neutral molecules together. At some point, these molecules have an induced dipole, which means they have a partially positive and partially negative charge for a brief period of time, leading them to attract one other.

They are forces of Van de Waals: The movement of electrons causes dispersion forces between non-polar molecules (union between atoms of the same element or between atoms with very little electronegativity difference).

Therefore, Vander Waal forces are the weak bonds formed when atoms and molecules are temporarily attracted to each other due to their proximity and charge.

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1. Always point a test tube a. away from you and toward others b. away from you and others c. toward you and others d. toward you and oney from others​

Answers

Answer:

away from you and others

Explanation:

is a carbohydrate that is formed by combining galactose and glucose. Which term best describes this molecule?

Answers

Answer:

Lactose is a carbohydrate that is formed by combining galactose and glucose.

Disaccharide is the term that best describes this molecule.

Explanation:

Disaccharide is the term used to signify substances that are made up of two simple sugar molecules. These molecules are connected to each other. Single sugars are also termed as monosaccharides. Disaccharides are substances that can easily dissolve in water. Sucrose, lactose, and maltose are the three main disaccharides.

How can a uniporter, GLUT2, be sufficient for entry of glucose from intestinal epithelial cells into the bloodstream?

Answers

Answer:

This is because we know the amount of Glucose inside the intestinal epithelial cell is higher than in the bloodstream so a uniport in the basolateral surface of the intestinal epithelial cell canbbe used to move glucose into the blood stream and it is the two-Na+/one-glucose symporter placed in the apical surface, acting as secondary active transport that generates the high amount of glucose inside the epithelial cell

What does this animation mean when it says that ATP is like a rechargeable battery?

Answers

I dont know what animation you mean about but i will give my opinion.

ATP are used for energy, they are made inside mitochondria. Mitochondria use oxygen and food to make ATP, which is maybe what u mean by rechargable is because whenever you eat, the mitochondria will produce energy again and again.

Hi Class, So, why does differentiation occur in an organization? Distinguish between vertical and horizontal differentiation.

Answers

Answer:

Differentiation occurs because as organizations grow and become more complex, they establish a division of work. Vertical differentiation is a ranking of power with reporting relationships established to connect organizational roles and sub-units. Where horizontal differentiation are group roles according to task responsibilities, establishes division of power, and forms sub-units.

When determining if the data accepted
or rejected your hypothesis, you are
A. Drawing conclusions
B. Asking questions
C. Summarizing the results
D. Forming a hypothesis

Answers

Answer:

c

Explanation:

When determining if the data accepted or rejected your hypothesis, you are summarizing the results.

What is a hypothesis?

Hypothesis testing is a scientific process of whether to accept or decline the statement. There are two types of hypothesis null hypothesis and alternative hypothesis.

If P value is less than the alpha then null hypothesis is rejected. If P value is greater than alpha then null hypothesis is not rejected. The level of significance is often called p value.

If we want to reject the null hypothesis, we need to follow given steps:

State the null hypothesis.Support or reject a null hypothesis.Find the critical valueFind the p value.

Therefore, When determining if the data accepted or rejected your hypothesis, you are summarizing the results. Option C is correct.

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What is the difference between cell and organelle?

Answers

Answer:

An organelle (think of it as a cell's internal organ) is a membrane bound structure found within a cell. Just like cells have membranes to hold everything in, these mini-organs are also bound in a double layer of phospholipids to insulate their little compartments within the larger cells.

Explanation:

Difference between cell and cell organelle:Cell:It is the structural and functional unit of life.It is also the smallest unit of life.It is bounded by a cell membrane or plasma membrane.The cell membrane, the nucleus, and the cytoplasm are the three primary components of a cell.There are two types of cells: prokaryotic cell (which does not contain membrane-bound nucleus and organelles) and eukaryotic cell (contains membrane-bound nucleus and organelles)

Cell organelles:These are the subcellular parts of a cell.They are surrounded either by a single membrane or double membrane.Eukaryotic cells contain membrane-bound organelles while prokaryotic cells do not have membrane-bound organelles.The various cell organelles are:NucleusRibosomesEndoplasmic reticulumGolgi apparatusChloroplastsMitochondria

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Reflect and Respond As you read through the research in Case Study: Sea Turtles, keep in mind the three basic steps of addressing challenges to ecological well-being. Answer these three questions as you review the information on the Everglades. Identify the problem(s) at hand. Determine the cause of the problem(s). Recommend solutions to the problem(s). A sample answer might include the following: Identify the problem(s) at hand. There are five species of sea turtles that live in the mid-Atlantic oceans of the United States. All five are on the Threatened or Endangered Species lists. Will increased use of offshore wind power technologies impact sea turtles? Determine the cause of the problem. Sea turtles face a variety of environmental dangers. Many are killed by accidentally getting caught in fishing nets. Many boats and ships run over the sea turtles, causing bodily damage or death to the turtles. Development of the coastlines impacts the nesting habitat of the turtles. Sea turtle nests are destroyed or damaged by predators or humans. Recommend solutions to the problem. Select locations for wind power technology and equipment that won’t impact sea turtle habitats.

Answers

Answer:

The nesting zone of ocean turtles could be saved and ensured with the assistance of commitment of neighborhood individuals , maintaining a strategic distance from of sea shore fires during settling season. A lot of advancement of sea shore territory leaves less ground for the turtles to cover for the settling processes,so less improvement of the sea shore.  

There ought to be insignificant lighting close to the nesting zones as angled turtles are pulled in to light and they may wind up moving towards the city as opposed to the water. Local people could shield the hatching eggs from being originated before by other wild creatures and feathered creatures by labeling them and keeping a nearby eye.  

Beach area cleanup ought to be basic as the debris are the significant reason forever danger to the turtles and all other marine creatures.  

During incubating and hatching period the coast line ought to be shut and forbidden to human obstruction. Additionally sheltered return of the ocean turtles subsequent to laying eggs and furthermore in the wake of bring forth of the eggs could be guaranteed by local people or the individual from any association working for the protected watchman of the turtles.  

Sun oriented force age and wind power age advances are in any case have an extremely lesser effect on turtle propensities. Be that as it may, as wind plants being set up in seaside regions it's being industrialized in this manner presents issue for turtles. Desert regions are a lot of appropriate too for age of both of these sort of intensity age methods along these lines sea shores remain sheltered and open for turtles to lay eggs.

Answer:

The nesting zone of ocean turtles could be saved and ensured with the assistance of commitment of neighborhood individuals, maintaining a strategic distance from of sea shore fires during settling season. A lot of advancement of sea shore territory leaves less ground for the turtles to cover for the settling processes, so less improvement of the sea shore.    

There ought to be insignificant lighting close to the nesting zones as angled turtles are pulled in to light and they may wind up moving towards the city as opposed to the water. Local people could shield the hatching eggs from being originated before by other wild creatures and feathered creatures by labeling them and keeping a nearby eye.    

Beach area cleanup ought to be basic as the debris are the significant reason forever danger to the turtles and all other marine creatures.    

During incubating and hatching period, the coast line ought to be shut and forbidden to human obstruction. Additionally sheltered return of the ocean turtles subsequent to laying eggs and furthermore in the wake of bring forth of the eggs could be guaranteed by local people or the individual from any association working for the protected watchman of the turtles.    

Sun oriented force age and wind power age advances are in any case have an extremely lesser effect on turtle propensities. Be that as it may, as wind plants being set up in seaside regions it's being industrialized in this manner presents issue for turtles. Desert regions are a lot of appropriate too for age of both of these sorts of intensity age methods along these lines' sea shores remain sheltered and open for turtles to lay eggs.  

 

Explanation:

Something that is like the real thing but not exactly

Answers

Answer: A synonym? Similar?

Explanation: Are you looking for a word or something else?

Describe the arrangement and general function of simple squamous epithelium.

Answers

Answer:

When  group of   tissues  are formed  from  a cell layer  of squamous cell,then the epithelium formed  is said to be simple squamous epithelium.These cells are  tightly packed together,to   form the lining of the cell surface.Thus they are in directs contact with the basement membrane underlying the cell structure.  Therefore,they act as selectively membrane structure for osmosis,diffusion,This explain their presence in the alveolar and kidney,where filtration  takes place

In  additions ,due to their  one cell layer thickness,they form the lining of fragile of delicate body cavities. e.g the alveolar in the lungs, lymphatic vessels,and inner lining of the wall of the heart.

Besides they also contain membrane proteins,which aids the control of substances across their walls  of tight junctions.Thus ions, molecules passages is regulated

Explanation:

The nitrogenous bases guanine and adenine are A. purines. B. a phosphate group. C. pyrimidines. D. a sugar group.

Answers

Answer:

The nitrogenous bases guanine and adenine are A. purines.

Explanation:

Adenine and guanine are purines, whereas the other two bases in DNA (thymine and cytosine) are pyrimidines.  The main difference between purines and pyrimidines is the number of rings that the base has: purines have two rings while pyrimidines only have one ring.  

In addition, phosphate group and sugar group cannot be the answer to this question because these two elements in addition to a nitrogenous base makes up a nucleotide.

Hope this helps!

Which of the following is true of an ecosystem?
A.There will be more herbivores than any other
organism in an ecosystem.
B.There will be more carnivores than any other
organism in an ecosystem.
C.There will be more carnivores than herbivores in an
ecosystem.
D.There will be more producers than herbivores in an
ecosystem

Answers

Answer:

D.There will be more producers than herbivores in an ecosystem

Explanation:

In an ecosystem, organisms feed on one another in order to obtain energy needed for their life processes. The series of chain by which organisms derive energy by feeding on one another is called FOOD CHAIN. A good chain always start with a PRODUCER (an organism capable of synthesizing its own food via photosynthesis). Organisms called HERBIVORES feed directly on the producers, and subsequently CARNIVORES feed on the herbivores.

According to the pyramid of numbers, which shows a graphical display of the number of organisms occupying each trophic level, the producers which are at the bottom of the pyramid are always more in number than any other organism in the food chain. It takes fewer herbivores to consume a large number of producers.

What is the function of enzymes in plants

Plz help ASAP
Thank you

Answers

Answer:

D. Produce simple glucose from sugars

Explanation:

Enzymes are regarded as biological catalysts that helps bring about biochemical reactions in living systems. They perform day-to-day activities in living cells including anabolism (build up molecules), catabolism (break down molecules) etc.

Amylase is an important group of enzymes found in plants. They catalyze reactions involving the break down of large carbohydrate molecules into simpler ones. Large polysaccharides like starch in plants are broken down to simple sugars like glucose with the help of catalytic enzymes called AMYLASES. The glucose is used to supply energy to the plant cells.

Describe Macromolecules
Carbo-
hydrates
Lipids Proteins
Nucleic
Acids
Fill in the information missing in the table to the
right by selecting the appropriate answer from the
drop-down menu.
A
Elements in
Molecules
carbon
hydrogen
oxygen
A
B
С
B
Building
Block
D
fatty
acid
m
F
С
D
E
T

Answers

Answer:

nitrogen, silicon, sodium, fluorine, diamond, phosphorus iron, copper,zinc,mercury,bronze,steel brass

Answer:

A- Carbon, hydrogen, oxygen, nitrogen

B- carbon, hydrogen, oxygen, nitrogen, phosphorus

C- sugar

D- amino acid

E-nucleotide

Explanation: just did it.

Given the following DNA template, what is the appropriate mRNA strand
3' TACTTCAAACCGATT 5'

Answers

Answer:

5' AUGAAGUUUGGCUAA 3'

Explanation:

The process by which the information encoded in a DNA is used as a template to synthesize a mRNA is called TRANSCRIPTION. It is the first stage of gene expression carried out in the nucleus of eukaryotic cells and cytoplasm of prokaryotic cells by RNA polymerase enzyme.

The process of transcription follows the complementary base pairing rule, which says that Adenine base always hydrogen pairs with Thymine while Guanine pairs with Cytosine. During transcription, the Thymine base (T) is replaced by Uracil base (U). Hence, whenever RNA polymerase reads an A in the DNA, it synthesizes U in the mRNA and vice versa for T and A. The same applies for G and C.

For the DNA sequence;

3' TACTTCAAACCGATT 5'

The mRNA sequence will be synthesized;

5' AUGAAGUUUGGCUAA 3'

Which type of cellular adaptation would create the greatest concern if found on a biopsy report? Dysplasia Metaplasia Hyperplasia Hypertrophy

Answers

Answer:

Dysplasia

Explanation:

Dysplasia has to do with the occurrence of abnormal growth of cells in tissues. In dysplasia, mature cells are replaced with less mature cells. These abnormal cells are referred to as dysplastic cells, and they have the potential of transforming to cancer cells. These are also referred to as preneoplastic lesions because in cancer development they precede neoplastic cells which cannot be reversed..

Metaplasia is the replacement of a well-differentiated (mature) with another mature cell. In cancer development, metaplasia precedes dysplasia.

Hypertrophy is the abnormal enlargement of tissues or organs as a result of the increase in the size of cells within the tissues or organs.

Hyperplasia is the abnormal enlargement of tissues or organs as a result of the increase in the number of cells within the tissues or organs.

Compared to others, Dysplasia has the greatest potential of becoming cancer; once dysplastic cells are formed it can easily morph to neoplastic cells which are cancer cells and that is why it will create the greatest concern if found on a biopsy report.

Which biomes is most likely to be found in areas that average 80 or more inches of precipitation a year?

Answers

Answer:

Equatorial rainforests

The type of rainforest and its location determines annual rainfall amounts: Equatorial rainforests receive more than 80 inches of rain annually.

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what monosaccharides make up maltose?

Answers

glucose and fructose

which statement best supports the RNA world hypothesis?

Answers

Answer:DNA molecules are a precursor to self-replicating RNA molecules, which are used to build proteins. Early RNA molecules were able to self-replicate, which helps to explain why all organisms share the same genetic code.

Answer:

B

Explanation:

Convert 0.37 kilograms to grams. ____ grams

Answers

Answer:

370

Explanation:

I took you test

According to unit conversion, 0.37 kilograms is equal to 370 grams.

Unit conversion is defined as a multi-step process which involves multiplication or a division operation by a numerical factor.The process of unit conversion requires selection of appropriate number of significant figures and the rounding off procedure.

It involves a conversion factor which is an expression for expressing the relationship between the two units.A conversion ratio always has value which equals to one which indicates that numerator and denominator have values which are expressed in different units.

As [tex]1[/tex] kg[tex]=1000[/tex] g,thus to convert [tex]0.37[/tex] kg to g the value needs to be multiplied by [tex]1000[/tex] giving ,

[tex]0.37[/tex]×[tex]1000[/tex]=[tex]370[/tex] g.

Thus, 0.37 kilograms is equal to 370 grams.

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List five item that can be found in a science portfolio

Answers

Answer:

A letter to the reader outlining each portfolio itemA list of term definitions that will be helpful to readersA collection of individual goals for the year, selected and updated by students monthly, quarterly, etc.Graphics—charts, concept diagrams, timelines, photographs, etc.—showing important data such as test scoresBook excerpts or quotations chosen by the studentA chart tracking every free-choice book a student has read that yearReading logsPhotographs of students workingAnecdotal notes from one-on-one or small group time with students (e.g. guided reading notes)Video recordings of readings or performances (for ePortfolios)A sample paragraph of writing featuring a few key writing techniquesSample essays of various types—descriptive, narrative, explanatory, expository, persuasive, cause and effect, and compare and contrast are all good optionsTechnical writing such as a process analysis essay featuring student-drawn diagramsCreative writing samples, including stories, poems, songs, and scriptsA collection of graded math quizzes showing performance trends

Insectivorous birds are more likely to eat medium sized insects because the exoskeleton of large insects is too hard to break, and small insects are too hard to find.
a. True
b. False

Answers

Answer:

Option A: True

Explanation:

Insectivorous birds such as bluebirds, dippers and flycatchers prefer to eat medium-sized insects. This is because like most birds, they love easy and satisfying meals. To the birds, a medium-sized insect is a good compromise because it is quite easy to chew and digest and at the same time, easy to find.

As a result, most insectivorous birds prefer to get their daily ration of proteins from the medium-sized birds.

Who was the last Scientist to make the last part of the cell theory?

Answers

Answer:

Robet Hooke

Explanation:

I could be Robert Hooke

In your words, describe why an astronauts weight is different on the moon than on the earth?!?!​

Answers

because weight depends.upon gravity and mass but gravity on earth d differs from gravitu on moon

Answer:

Explanation :The Earth's Moon has considerably less mass than the Earth itself. And also the gravitational attraction on the Moon is much less than it is here on Earth, and a person weighs less on the Moon

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After hurricane Irma, and partially trigger by news distributed by social media during that period, people in Ecuador (particularly in coastal places) have started to worry that changes in climate will translate into having tropical cyclones of similar magnitude hitting their country. After all, unusual patterns of rainfall, increase temperature that is melting glaciers in the Andes, etc., are relatively new climate-related events easily perceivable by people. As a climate expert, please explain to Ecuadorians briefly: 1)how tropical cyclones are formed and where they occur globally mentioning key factors for their formation and for them to gain strength; 2) using the previous information, discuss whether or not they have reason to worry about a tropical cyclone of high magnitude hitting Ecuador as a result of changes in climate.

Answers

Answer:

1. Cyclones are one of nature’s responses in which winds move in a circular motion when hot and cold air currents meet under low atmospheric pressure.

Tropical cyclone formation takes place when sea-surface temperature rises and meet with vertical wind shear and high relative humidity leads to a winds swirl around the area of low atmospheric pressure.

2. Yes, people have reason to worry about a tropical cyclone of high magnitude hitting Ecuador as a result of changes in climate because due to climate change, sea-surface temperature is rising continuously which can lead to cyclone of high magnitude and come with more disaster.

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