Choose the true statements about amyloid fibrils. 3 options are correct.
1) Because most newly synthesized proteins fold correctly, the accumulation of misfolded proteins (or fragments) tends to occur slowly, thus explaining the slow onset of disease.
2) An amyloid fibril typically forms from aggregates of misfolded peptides resulting from frameshift mutations.
3) An amyloid fibril is stabilized by hydrophobic interactions between aromatic residues.
4) Soluble proteins that misfold and form amyloid fibrils become insoluble.
5) Proteins that convert to an amyloid fibril structure tend to have low solubility in their native form.

Answers

Answer 1

Answer:

Options 1, 3 and 4.

Because most newly synthesized proteins fold correctly, the accumulation of misfolded proteins (or fragments) tends to occur slowly, thus explaining the slow onset of disease.

An amyloid fibril is stabilized by hydrophobic interactions between aromatic residues.

4) Soluble proteins that misfold and form amyloid fibrils become insoluble.

Explanation:

Amloid fibrils are peptide or proteins that are formed during invivo or invitro conditions. They ate formed when soluble proteins combine together to for insoluble fibres that are resistant to degradation. They are found in extracellular tissues and posses pathological effect. They accumulate after nerve cells and causes several illness.

An amyloid fibril is stabilized by hydrophobic interactions between aromatic residues.

4) Soluble proteins that misfold and form amyloid fibrils become insoluble.

An amyloid fibril is stabilized by hydrophobic interactions between aromatic residues.

Soluble proteins that misfold and form amyloid fibrils become insoluble.

Answer 2

Answer:

The correct answers are options 1) "Because most newly synthesized proteins fold correctly, the accumulation of misfolded proteins (or fragments) tends to occur slowly, thus explaining the slow onset of disease". 3) "An amyloid fibril is stabilized by hydrophobic interactions between aromatic residues", and 4) "Soluble proteins that misfold and form amyloid fibrils become insoluble".

Explanation:

Amyloid fibrils are protein aggregates that can cause pathological conditions, for instance, they are found in brain tissue in people with Alzheimer disease. This disease, and other relates diseases, have a slow onset because most newly synthesized proteins fold correctly and the protein aggregates are made up misfolded proteins. This newly synthesized proteins are soluble, but once the proteins are misfolded, they form amyloid fibrils that are insoluble. The amyloid fibrils are stabilized by hydrophobic interactions between aromatic residues, which are formed within the complex of insoluble misfolded proteins.


Related Questions

The graph shows the populations of two species in a particular region over two decades. Based on the graph, what can you conclude about the relationship between the two species?

Answers

The correct answer is - B. Mutualistic. The symbiotic relationship shown in this graph is most likely a mutualistic symbiotic relationship. in a mutualistic symbiotic relationship, the two species benefit from one another, in a way they collaborate for the well-being of both of them. this leads to a situation where the increase in numbers of one of the species, the other species also experiences increase in numbers, and if one of them has a decrease in numbers, it is very likely that the other species will experience the same. in this graph we have exactly that kind of situation one of the species experiences increasing in numbers, and the other species follows the same pattern, which most likely means that a mutualistic symbiotic relationship exist between the two species.

The two species are mutualistic in nature. The two species exhibit commensalism.

What are the negative effects of rising ocean temperatures? Check all that apply
the melting of glaciers and polar ice caps
the drying out of fertile land and the formation of dust bowls
the flooding of low-lying coastal areas
the faster evaporation of water in the soil
the decreased frequency of major storms

Answers

Answer:

the melting of glaciers and polar ice caps

and

the flooding of low-lying coastal areas

Explanation:

Answer:B

Explanation:I got it right.

the process when organisms reproduce, they pass their characteristics on to their offspring.

Answers

Answer:evolution

Explanation:Evolution describes changes in inherited traits of populations through successive generations. To fully understand the science of ecology, one must first be able to grasp evolutionary concepts.

When water goes from being a liquid to a gas without boiling, the water______. A evaporates B condenses C precipitates D boils PLEASE HURRY IN A TEST!!!!!!!

Answers

Answer:

A

Explanation:

mark brainlest plz hope it helps

Answer:

A. evaporates

Explanation:

Compare the advantages and disadvantages of demolishing an old building versus renovating it.

Answers

Answer:

Demolishing a building involves pulling down the whole structure and building from the scratch while renovation doesn’t involve pulling down the whole structure. It involves pulling down some parts of the building or simply modifying the building.

An advantage of Demolition is that the individual is able to build from the scratch which permits him/her to have the exact structure wanted.

A disadvantage of this is the high cost incurred on demolition and building from the scratch.

An advantage of Renovation is the less cost involved since it only requires some modifications and not total pulling down of the structure.

A disadvantage of Renovation is the inability to get the exact building taste the individual hoped for.

Which two classes make up the majority of crustaceans?

Answers

Answer:yes

Explanation:

The ozone has been depleted (reduced/ damaged) by many man-made chemicals that have been released into the atmosphere. If the presence of these chemicals continues to stay the same (or increase), it is reasonable to predict that

A organisms would develop higher rates of asthma.
B all life on Earth would eventually freeze.
C freshwater would become salt water.
D more ultraviolet radiation would penetrate to Earth's surface, furthering current global warming trends.

Answers

Answer:

More ultraviolet radiation would penetrate to Earth's surface, furthering current global warming trends.

Saliva helps to break down food chemically by using enzymes. Which statement best describes this process?

Answers

Answer:

the enzyme helps to break down food, the enzyme is in the

saliva. It can break down a big food molecules and divide it into a

simpler food molecules so that it can be digested. . Enzymes are

complex proteins that speed up the rate of chemical reactions.

How are genes cloned

Answers

Answer:Gene cloning is the process in which a gene of interest is located and copied (cloned) out of DNA extracted from an organism. When DNA is extracted from an organism, all of its genes are extracted at one time. ... The genetic engineer must find the one specific gene that encodes the specific protein of interest.

Explanation:

Explain why scientists the Albert and kaibab squirrels are examples of speciation

Answers

- Kaibab Squirrel gives us one nice example of the evolution that is caused by geographical isolation - about 10,000 years ago when the last Ice Age ended, physical formations in the valley changed in a way that prevented squirrels from reaching the Colorado River. The valley has become a geographical barrier separating forests and squirrels on each edge. One group of squirrels became two separate groups that were no longer able to mate, kaibab squirrels. Abert squirrels are North American species, found across a group of locations. Kaibab squirrels are a subspecies of Abert squirrels, found only in one region in the United States. - Kaibab and Abert squirrel live in ponderosa pine forests, where they build nests of twigs and pine needles. They eat nuts, fruits, and fungi, as well as seeds, bark and twigs from the trees they make at home. The most important source of food in the squirrel Kaibab is the seeds contained in the cones of ponderosa

Answer:

The Abert’s squirrel is found on the south rim of the grand canyon and surrounding states.

The Kaibab squirrel can only be found at the north rim of the canyon.

Scientists believe they were separated by plateau erosion that separated the forests of the Grand Canyon, isolating the Kaibab population of squirrels.

Explanation:

What about these molecules requires them to have this tetrahedron shape?

Answers

Answer:

There are four atoms required for having tetrahedron shape.

Explanation:

Tetrahedron shape molecule is made up of four atoms. The structure of tetrahedron shape molecule is just like pyramid. One atom is present at the top while the remaining three atoms attached to it at the bottom with bond angles of about 109.5°. So the structure of molecules only be possible if the molecule is made up of at least four atoms and have four unpaired electrons. Examples of such molecules are methane, water and ammonia.

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Answers

The correct answer is A. Fracture

Explanation:

A fracture occurs when a mineral, for example, calcite or quartz breaks in an irregular pattern. Fractures can occur due to multiple factors including pressure, temperature, among others. Additionally, fractures the term "fracture" differs from the term "cleavage" because in fractures breaks are irregular while in cleavage minerals break in a definite structure along the structural planes of the mineral. Thus, a fracture is the irregular break of a mineral.

In a community, before biomass is widely used as an energy source, several experts, including an ecologist,are hired to provide specific information. The ecologist would most likely be asked about

Answers

Answer:

The ecologist provide information about the ecosystem.

Explanation:

The ecologist is a person who provide information about the relationship between organism and its environment. The ecologist tell the people about the benefits of plants that exist in our environment. Biomass is widely used as source of energy in a community which is gained from cutting of trees. The removal of trees causes damage to the whole ecosystem so the people of community used less biomass or other materials as a source of energy.

What competitive processes or forces are ever-present during a star's lifetime?

Answers

Answer:

Force of Gravity

Explanation:

It should be understood that just like all other lives, the stars are also produced and die at a given or specific time.

And during its course of living, it is bound to struggle with the gravitational force or force of gravity through its entire life.

Scientists must be able to repeat an experiment and get very similar results; otherwise their conclusions will be questioned. If
the results of a repeated experiment are different from the original results, the results of the experiment
lack bias
are precise.
lack controls.
are flawed.

Answers

the result of the experiment is precise

Answer:

are flawed

Explanation:

got it right on e2020

A female rabbit can give birth to over 40 baby rabbits a year. Suppose all of her
offspring survived and reproduced, all of their offspring survived and
reproduced, and so on. If that happened, in only eight years the mass of rabbits
would exceed the mass of Earth! So, why aren't we overrun with rabbits? What
keeps the rabbit population in check?

Answers

Answer:

Predeators such as us and others that eat these rabbits keep their population in check. Also these rebbots that are being born will die soon also, menaing their popultaion is filling and taking away, then refilling again and again with them dying.

Explanation:

The population of rabbits could have overrun human population ordinarily, but the presence of limiting factors would hinder it.

The limiting factors are biotic and abiotic environmental factors that prevents the population of organisms from getting to their biotic potential. In other words, limiting factors will not let the population of organisms grow perpetually. These factors include:

Competition for limited resourcesDiseasesNatural disastersPredation

In the real sense, the earth has the maximum number of individuals from each species it can support based on the resources it has, otherwise known as carrying capacity. Thus, the population of any species of living organism cannot grow without checks.

More on limiting factors of populations can be found here: https://brainly.com/question/24077456

What are the primary pigment colors?


magenta, turquoise, and violet

yellow, red, and green

cyan, yellow, and magenta

red, green, and blue

Answers

Answer:

the answer would be red green and blue because those are the three base colors in art aswell as for film cameras

Answer:

(This is a guess) Red, green, and blue seem as if they are primary colors!

Explanation:

I might be a little late, but if I'm not.. can I please have brainliest? (If I am correct) :)

brainliest !!!!!!!!!!!

Answers

Answer:

3rd choice

Explanation:

Organism 1 has chloroplasts which is where photosynthesis takes place. Photosynthesis is the process for plants to use sunlight, carbon dioxide, and water to produce glucose and oxygen. Sunlight is solar energy and glucose is an energy-rich compound.

Answer:

3rd Choice

Explanation:

The plane of Earth's orbit around the Sun is called the: ?

Answers

Answer:

its called The Ecliptic.

Explanation:

The plane of Earth's orbit around the Sun is called the "ecliptic plane." The ecliptic plane is an imaginary flat plane that represents the average path traced by Earth as it orbits the Sun.

The Ecliptic plane serves as a reference plane for locating the positions of celestial objects in the sky, including the Sun, Moon, planets, and stars. The ecliptic plane is inclined at an angle of approximately 23.5 degrees with respect to Earth's equator, giving rise to the changing seasons as Earth orbits the Sun.

Therefore, the ecliptic plane represents the average path of Earth's orbit around the Sun and serves as a reference for understanding celestial positions and movements. Its tilt plays a vital role in determining Earth's seasons, and its alignment with other planets enables various astronomical phenomena.

For more details regarding Earth's orbit, visit:

https://brainly.com/question/32021664

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Select a type of renewable energy

Answers

solar energy, wind energy, hydropower, geothermal energy, and biomass energy. These types of energy sources are different from fossil fuels, such as coal, oil, and natural gas.

Choose the correct option
An Insect that live in colony is
1) Ants
2) Dragon fly
3) House fly

Answers

The answer is 1) Ants

How has society influenced science during the pandemic?

Answers

Answer:

society have  been more careful from diseases and people are learning their lesson not to eat things that we are not supposed to eat

Explanation:

#allivesmatter

The solubility of solid in a liquid __________________ with the increase in temperature.

Answers

Answer:

solubility increases witn increase in temperature

Answer:

increases

Explanation:

As temp increases, avg kinetic energy of solvent molecules increases, and move faster randomly in all directions. As a result, the no. of collision between solvent and solid per unit time increases, hence rate of dissolving increases.

what is a dependent variable​

Answers

A dependent variable is exactly what it sounds like it is something that depends on other factors for example a test score could be a dependent variable because it could change depending on several factors such as how much you studied how much sleep you got the night before you took the test or even how hungry you were when you took it. Usually when you are looking for a relationship between two things you are trying to find out what makes the D pendant variable change the way it does.

Many people have trouble Remembering which is the independent variable and which is the dependent variable. An easy way to remember is to insert the names of two variables you are using in the sentence in the way that makes more sense to you. Then you can figure out which is the independent variable and which is a dependent variable.

the Independent variable causes a change in the dependent variable and it isn’t possible that the dependent variable could cause change in the dependent variable

I need help please and thank you

Answers

Answer:

A. Competitive .

Explanation:

because they are both trying to get the same resource .

Hope it helps you !!

Fragile marine ecosystems have been destroyed in the production of this type of energy.

water energy

nuclear energy

fossil fuel energy

geothermal energy

Answers

Answer:

Fossil fuel energy

Explanation:

Temperatures keep rising causing ocean levels to rise or fall

The cell pictured is in metaphase. Which stage of mitosis will the cell be in NEXT?
a) anaphase
b) telophase
c) cytokinesis
d) prophase

Answers

The mitosis and and meiosis question you asked disappeared for me but the answer is 2 daughter cells

you are working as a medic at a gymnastics competition, and one of the gymnasts has a bad landing after a vault, injuring her leg. Her leg is bent at an awkward angle and her tibia and fibula are obviously fractured. you palpitate her posterior tibia and dorsalis pedis pulses on her non-injured limb and they are 2/4. However, on her injured limb, they are 0/4. you also notice that her injured limb is becoming pale and cold to the touch distal to the injury. What has likely happened? Explain.

Answers

Answer:

The bone has broken and either severed or blocked the blood vessels

Explanation:

Please help me with this

Answers

answer:is interphase

Based on fossil evidence, about how long ago did the first single celled life fork appear on earth?

Answers

Answer:

it was exactly 3.5 billion years ago

Explanation:

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