Normal cells die in a nutrient medium containing thymidine and methotrexate, whereas mutant cells defective in thymidylate synthase survive and grow. The mutant cells grow because the medium contains the___________ they are unable to make normal cells, however, continue to synthesize their own and thereby convert their limited supply of to________ . The methotrexate inhibits , so cannot be regenerated. Without a supply of___________ for the synthesis of nucleotides and amino acids, the cells die.

Answers

Answer 1

Answer:

*Thymidine

*THF to DHF

*THF

Explanation:

Normal cells die in a nutrient medium containing thymidine and methotrexate, whereas mutant cells defective in thymidylate synthase survive and grow. The mutant cells grow because the medium contains the_____Thymidine______ they are unable to make normal cells, however, continue to synthesize their own and thereby convert their limited supply of to__THF to DHF______ . The methotrexate inhibits , so cannot be regenerated. Without a supply of______THF_____ for the synthesis of nucleotides and amino acids, the cells die.

NOTE:

THF means Tetrahydrofolate

DHF means Dihydrofolate

Thymidine which is also reffered to as deoxythymidine, is described as a deoxynucleoside that is composed of the pyrimidine base thymine that is attached to the sugar deoxyribose. Thymidine is a nucleoside made up of pentose sugar, pyrimidine base tymine and deoxyribose, it is one of the the four nucleoside found in exclusively DNA as well as T-loop of tRNA.

Tetrahydrofolate also known as tetrahydrofolic acid can be described as part of folic acid that function as a coenzyme which aid metabolic reactions that includes nucleic acid and amino acids. It is also reffered to as one-carbon metabolism, and it's oone-carbon mechanism is associated to the histidine, serine of amino acid.


Related Questions

d. How is shadow form? Give example of shadows when the sun is behind, top and front of up. Draw and show.​

Answers

Answer:

Shadow is formed when an opaque object blocks the rays of light.

When the son is at top the shadow is seen down and long

When the sun is behind the shadow is seen shorter in comparison

When the sun is at front of us the shadow is seen backup of us

Hope u have understood

Mark my answer as brainliest

I love you would you like to be my valentine

Answer:

Shadow is formed when an opaque object blocks the rays of light.

Sara read in a book that in 1800, the Italian physicist Alessandro Volta observed that two metals connected by a conducting liquid produced a continuous transfer of electrons. This phenomenon was different from the rapid static discharge observed by Benjamin Franklin.

Sara’s book was describing Volta’s observation of:

Answers

Answer:

the process described in the question, described by Alessandro Volta refers to superconductivity, in which two metals connected by a conductive liquid produce a continuous transfer of electrons, these metals are considered superconductors since they do not have electrical resistance and this is always maintained and when the temperature is adequate, different from terms such as the resistance that is the impediment to the flow passage, or to the electric static in which the energy accumulation is maintained without movement or transfer or the electric current that is the energy in the same metal.

Answer:

C) Electric current, which is the flow of electrons through a material.

Explanation:

The hypothalamus controls excretions from the pituitary gland. It causes the release of some hormones from the pituitary by direct nervous control, and others by secreting releasing and inhibiting factors that stimulate the pituitary to secrete hormones. Which best describes the hypothalamus?

Answers

Answer:

It causes the release of some hormones from the pituitary,,,,

Please help me with 4 through 6

Answers

4.b 5.c 6.c is the right answer

What reasoning correctly pairs a body system with its relationship to the digestive system?

Answers

Answer:

Respiratory system.

Explanation:

This is the system which shows a good pairing with the digestive system. This is because for energy to be synthesized by oxidative phosphorylation,  respiratory systems need  the supply of  Oxygen. The oxygen is needed to accept the final electron in the synthesis of ATPs during oxidative phosphorylation.

This process begins with substrate level phosphorylation-glycolysis- the breaking down of glucose from the digestive system.

Hence, respiratory system needs  the  supply of oxygen for the metabolisms of glucose obtained from digestive system to generate energy( extract the energy in glucose) for the body.

ecology succession biology succession ​

Answers

Answer:

There are two types of succession.

Primary Succession - A bare mass of rock developing an ecosystem from scratch. It will use lichens and moss to create soil... a good example of this is a new land mass formed by a volcano.

Secondary Succession - A environment and ecosystem that was destroyed but does not need to start from scratch. It just needs the plants to regrow and attract wildlife back again... a good example of this is a forest destroyed by a wildfire.  

Explanation:

2. What does ectothermic mean?​

Answers

Answer:

Ectotherm, any so-called cold-blooded animal—that is, any animal whose regulation of body temperature depends on external sources, such as sunlight or a heated rock surface. The ectotherms include the fishes, amphibians, reptiles, and invertebrates.

Explanation:

how do oxbow lakes form​

Answers

Answer:

It starts with a bend in a river then the river erodes the bend until it goes through the bend and the old bend keeps its water and becomes a lake

Answer:

here you go

Explanation:

when you get a meander the lake slowly erodes from the inside, because water will always want to take the faster route( which would be straight ) the lake will slowly cute off the meander while dumping the rivers load forming an oxbow lake

A population of western skinks, a type of lizard, lives in a grassland habitat along the base of a mountain range. The construction of a multi-lane highway will divide the habitat into two separate regions. How will the construction of the highway most likely affect the western skink population?

Answers

Answer:

The western skink population would be separated into two groups, and genetic diversity would decline in each group.

Explanation:

It can be explained with the help of a bottleneck effect due to which population size decreases suddenly due to events like a natural disaster, habitat destruction etc.

You need to refuel your PWC. When should you check for gas fumes?

Answers

Options are not provided in the question. The complete question is:

You need to refuel your PWC. When should you check for gas fumes?

A. before fueling

B. while fueling

C. after fueling and before starting the engine

D. after fueling and restarting the engine

Answer:

C. after fueling and before starting the engine

Explanation:

A personal watercraft (PWC) is popularly known as jet skis or water scooter which run over water as its name suggest and ride by a rider who either sits or stands on the PWC rather than sitting inside of.

PWC run on unleaded gasoline and premium gasoline. Gas fumes in PWC is required to check after fueling and before starting the engine because if the tank will overfilled, fuel can expand into the water or leakage can cause explosion as well. After fueling and just before staring the engine it is must to check for evidence of gas fumes and one is smelling gas fumes, the source need to repair immediately.

Hence, the correct option is C.

Which of the following is true about the genetic code?

Answers

Answer:

It is universal among all life on Earth.

Explanation:

Several different codons may encode the same amino acid is true about the genetic code.

What is a Codon?

This is referred to as a sequence of three nucleotides which match a corresponding amino acid and useful in protein synthesis.

Different codons may encode the amino acid as a result of how they bind to transfer RNA (tRNA) which makes it the most appropriate choice.

Read more about Genetic code here https://brainly.com/question/1287470

What are two factors that determine an object's thermal energy?

Answers

Answer: MASS AND TEMPATURE

An object's thermal energy is dependent upon its temperature and mass. The higher the temperature of a given quantity of a substance, more is its thermal energy. Similarly, for the same temperature, higher mass of a substance will contain more thermal energy.

Explanation:

Two factors that determine an object's thermal energy are Mass and temperature.

Mass:

The mass of an object influences its thermal energy. The greater the mass of an object, the more thermal energy it possesses. This is because a larger mass contains a larger number of particles that are in motion, contributing to the overall thermal energy of the object.

Temperature:

The temperature of an object is a measure of the average kinetic energy of its particles. The higher the temperature, the greater the average kinetic energy and thus the greater the thermal energy of the object. Temperature determines the intensity of the thermal energy and how vigorously the particles are moving.

Thus, mass and temperature, play significant roles in determining the thermal energy of an object.

To know more about Thermal energy, click here;

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What causes changes in the sizes, shapes, and positions of Earth's continents and oceans?

A.
very strong ocean currents
B.
global wind belts
C.
continental drift
D.
tectonic plate motion

Answers

Answer:

D

Explanation:

I got it right

Tectonic plate motion causes changes in the sizes, shapes, and the positions of the Earth's continents and oceans. Thus, the correct option is D.

What is Tectonic plate motion?

Tectonic plates are the gigantic pieces of the Earth's crust and the uppermost mantle of the Earth. These layers of the earth are made up of oceanic crust and continental crust. Earthquakes mainly occurs around the mid-ocean ridges and the large faults which mark the edges of the plates in the Earth.

The heat from radioactive processes within the planet's interior causes these tectonic plates to move, which sometimes results towards and sometimes away from each other. This movement of the tectonic plates is called as plate motion or tectonic shift.

Therefore, the correct option is D.

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Seif’s pet mouse had babies. Five of the babies were black and two were white. The father mouse was black. The mother mouse was white. Seif and his friends wondered why the mice were different colors.

These were their ideas:

Jerome: Baby mice inherit more traits from their fathers than their mothers.

Alexa: Te baby mice got half their traits from their father and half from their mother.

June: Male traits are stronger than female traits.

Seif: Black mice have more traits than white mice.

Fiona: The black baby mice are probably male and the white baby mice are probably female.

Lydia: Parent’s traits like fur color don’t matter—nature decides what something will look like.

Billy: Blood type determines what traits babies will have.

Which friend do you most agree with and why? Explain your thinking.

Answers

Answer:

Lydia

Explanation:

The black fur in mice is probably more the dominant-inherited trait. The white fur is probably a recessive gene so less of the baby mice will have white fur.

The characters of offspring is decided by their traits, which they get from their father and mother. Sefi's pet mice have different colors because it got half traits from mother and half from father.

What is genetic inheritance?

Genetic inheritance means transfer of characters from parents to offspring. Due to this reason, offspring have characters from both father and mother.

This process is based on Mendalian principle. Any character of offspring is determined by both father and mother, not from the single one.

Here, as the father mouse was black and the mother mouse was white, so according to Mendalian principal, there were difference in the colors of baby mice.

Thus, one should be agree with Alexa, who gave an idea that the baby mice got half their traits from their father and half from their mother.

For more information about inheritance, visit:

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I need help please and thank you

Answers

I think the answer is commensalism because the organism that does the digging is unaffected in relation to the other organism who actually benefits by having an already made home (the hole) for protection & shelter.

When the CAU anticodon of a tRNAMet was modified to UAC, the anticodon for tRNAVal, valine aminoacyl-tRNA synthetase, recognized the altered tRNAMet and added valine rather than methionine to it. When the converse modification was made, the altered tRNAValcontaining a CAU anticodon (rather than UAC) was recognized and activated by methionine aminoacyl-tRNA synthetase. What do these data suggest about the mechanism by which aminoacyl-tRNA synthetases recognize their cognate tRNAs

Answers

Answer:

With the information obtained, it can be deduced that the tRNA anticodon region is recognized by an aminoacyl-tRNA synthetase, however some of these enzymes may have different elements in their structure and which would be the majority and which may trigger a fundamental role in the aminoacyl-tRNA synthetase recognition

Which two activities provide the reactants for cellular respiration

Answers

Answer:

The Reactants

Explanation:

Oxygen and Glucose are both reactants of cellular respiration.Oxygen enters the body when an organism breathes.Glucose enters the body when an organism eats.

Answer:

D-breathing in air and eating food

Explanation:

on edge plz give me brainly

brainliest if your right

Answers

C- Below 200 (It’s boiling point is 197.6)

If you see a diseased plant, it is most likely in the
stage of its life cycle.
O adult
death
growth
beginning
NEKOGU
NE HAUESTION
ASK FOR HELP

Answers

Death would be your answer cause diseased means death

TGC TAC GGC AAG transcribed into RNA

Answers

Answer:

sorry I don't know understand

HELP NOWWWWWWWWWWWWWW
Fill in the blanks with the correct word or phrase

The process of change in a population overtime is called --------------

The process by which organisms that are better adapted to the environment survive and reproduce is called --------------------

Answers

Answer: Microevolution.

Explanation: Microevolution is the change in allele frequencies that occurs over time within a population..

Mitochondria are vital to cells by carrying out which of the following functions

Answers

Answer:

Cellular Respiration.

Explanation:

Mitchondria are cell organelles that are essential to cells due to them being the site of Cellular Respiration. This is how cells produce energy to function by the use of Oxygen and breaking down Glucose molecules.

CID is a neurological disease believed to be caused
by prions, pathogenic agents that are smaller than
viruses, and are extremely resistant to inactivation
by heat and disinfecting agents. The incubation
period can be many years long and death is almost
certain within a year after initial onset of symptoms. What is the Main Point and What is the sub points?​

Answers

Answer:

Main point: CID is a lethal disease caused by prions.

Sub-points:

CID is a neurological disease (this means that it affects the nervous system.)Prions are pathogenic agents (this means disease-causing or harmful) that are smaller than viruses.They are resistant to inactivation by heat and disinfecting agents (this means that they're really hard to kill, because they're technically just misfolded proteins.)The incubation period can be many years long. (as in, symptoms may not show for a long period, but the prions are sitting in your body incubating and biding their time.)There's a very high mortality rate a year after symptoms show.

how is martinluther?

Answers

Answer:

Explanation:

dead... he is an iconic african-american who was a civil rights leader and gave a speech ¨I had a dream" in Washington D.C.

Answer:

who is martin luther a german professor

Explanation:

martin was a German professor of theology, composer, priest, Augustinian monk, and a seminal figure in the Protestant Reformation.

the big five does not include

Answers

Answer:

can you post a picture of the question

Explanation:

Answer:

What are the options?

Explanation:

The big five INCLUDES

Openness, conscientiousness, extraversion, agreeableness, and neuroticism

or OCEAN.

Have a good day and stay safe!

A plane that divides an animal into dorsal and ventral portions is _______________.

A) Sagittal
B) Midsagittal
C) Coronal
D) Transverse

Answers

Answer:

Coronal

Explanation:

A frontal plane (also called a coronal plane) separates the front (ventral) from the back (dorsal).

Which of the following is not true about the matter in ecosystems?

A) matter is recycled over and over in ecosystems

B) Biogeochemical cycles transfer or use nutrients in ecosystems

C) matter in an ecosystem flows in one direction and is never reused

Answers

Answer:

c) matter in an ecosystem flows in one direction and is never reused.

Explanation:

A is true

C is the answer to your question .

What are the similarities and differences between a predator-prey relationship and a herbivore-plant relationship?

Answers

Answer:

Predator-prey relationship and a herbivore-plant relationship have some of the similarities and some differences.

Similarities:

In both relationship,  Predator-prey and a herbivore-plant, the interaction is between two species in which one organism or species fed over other organism. in predator-prey relationship, predator is the species that fed over prey and in herbivore-plant relationship, herbivores are the species that fed over plants. So, both are type of predation .In both relationship, one species dependent on other for their survival or food.Both relationship controls the size of recessive species such as prey and plants in the environment.

Differences:

herbivore-plant has mutual interaction as herbivores eat plants and also helps plants to spread their seed and when animals die it decompose to the soil which is beneficial for plant growth while this is not same with predator-prey relationship, they have symbiotic relationship.In herbivore-plant relationship, the plants are unable to move in order to defend themselves except some mechanical advantages while in predator-prey relationship, prey can move themselves and fight for their survival

Hence,  predator-prey relationship and a herbivore-plant relationship have some similarities and differences as well.

What is a visual model used to measure the average amount of dietary intake of a black bear.

Answers

Answer:

Shaggy black fur and large size distinguish this animal from all other Adirondack mammals. The black bear has a short, inconspicuous tail. The body and legs are short. The head is broad with erect, rounded ears. The muzzle, grizzled with brown, is long and narrow. The eyes are small and dark. Both front and hind feet have five toes, each with a large claw. A white blaze is often present on the throat or chest. Color phases occur but are uncommon in eastern populations. Adults are approximately 50 -78 inches in length. Average-sized adult males weigh 300 lbs. and females 150 lbs.

Explanation:

Why couldnt water vapor have come to the earth when it was created?

a. All the water vapor was directed to Mars.
b. The atoms forming water were too light to stay in the inner Solar System and were blown out by the solar winds.
c. Water wasn’t around at the time.
d. There was no hydrogen in the solar system at that time.

Answers

Answer: The answer is B

Explanation:

A is not practically possible as mars is such a great distance away

C water of course wasnt around in earth at the time but other planets did have water so this isnt an accurate answer

D cracks me up, Hydrogen was the first element in space after the Big Bang this is also an in accurate answer

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