Many of the phenotypes of DiGeorge syndrome have been traced back to one of the genes that is in the deleted region, TBX1. Some of the evidence for the important role of TBX1 in DiGeorge syndrome came from individuals who have some of the symptoms of DiGeorge syndrome without having the typical deletion. Closer examination showed that some of these individuals had SNV in the TBX1 gene. Which of the following SNVS would be most likely to create a similar phenotype to the deletion?
A. A variant in the promoter region of TBX1 that increases its expression
B. A variant in the intronic region of TBX1 that does not affect splicing. X
C. A nonsense variant near the 5' end of the TBX1 gene.
D. A silent variant near the 5' end of the TBX1 gene.

Answers

Answer 1

Answer:

D. A silent variant near the 5' end of the TBX1 gene.

Explanation:

TBX1 gene is wild type human being. It gives instructions for making protein called T-box 1. It plays an important role in tissue formation and organs during embryonic development.


Related Questions

define cell and atom.....​

Answers

Answer:

cells are the basic building blocks of all organisms , whether living or dead.

atoms are the basic building blocks of matter(non-living things) . every item , for eg, chair, book, toothbrush are made of atoms?

Why do you think taking an action or providing measures to prevent disasters ever though you are not experiencing it yet is important?​

Answers

because it not only benefits you but large sums of people as well. it can prevent future disastrous outcomes and doing something even small has a huge impact. instead of having the mentality that it won’t change anything for you, consider how it will change for others and the earth itself

Why is it important that saline solution has a specific concentration when a person is put on an IV drip of saline?

Answers

Answer:

Doctors utilize IV saline for refilling lost fluids, flushing wounds, providing medication, and maintaining patients through surgery, dialysis, and chemical treatment. As a fashionable therapy, Saline IVs even found a space outside the hospital.

"There are significant quantities of sodium and chloride, higher than blood levels.

Explanation:

The solution of sodium chloride-water, generally known as saline, is the saline solution. It is the intravenous fluid most usually used. It was utilized since the early decades of the 19th century and is used annually in the United States alone with more than 200 million liters.

Though about 60 percent of the body consists of water, it is not possible to inject water into the blood alone, because the blood could lead to the depletion of important electrolytes.

Direct water injection into the bloodstream would likewise lead to the blood cells' osmotic impact.

Blood cells, which are predominantly salty, will take water and cause it to expand quickly until the cell membrane breaks down. The content of the cells would then leak into the plasma. A substantial proportion of body cells can be damaged to death. Death can result.

There would be no permanent harm to a little amount of water injected into the blood directly. The bigger the number of cells injured, in essence, the more water injects into the circulation.

Water is blended in a solution in sodium and chlorine at approximately the same concentration as blood plasma to avoid damages caused by pure distilled water on blood cells. The outcome is that the solution splits the circulating volume with the cellular fluid and becomes an integral part of the circulating volume without a detrimental influence on blood cells.

D - Telophase
C - Anaphase
A - Prophase
B - Metaphase
th
Choose the correct description for each phase of mitosis.

Answers

Answer:

A-B-C-D

Explanation:

PROPHASE; 1. chromosomes become thicker

2. nuclear membrane disintegrates

3. centrosome divide to form centrioles

4. centrioles move to the opposite polls of the cell

METAPHASE; 1. chromosomes get arranged at the equator

2. centrioles produce spindle fibre that attach to the middle of the chromosomes

ANAPHASE; 1. shortest stage of mitosis

2. spindles will pull apart each chromosomes to form chromatids

TELLOPHASE; 1.  each chromatid moves to opposite polls of the cell

2. nuclear membrane appears around both of them

3. the centrioles sill stop producing spindles

4. centrosomes will then form again

cytokinesis then divides by the cleavage furrow to form the two daughter cells

Quick quick !!

Which problem affects the global economy in addition to a local economy?
A. A citywide power outage
B. Drought on an island
C. Water pollution in a lake
D. Pollution of the atmosphere

Answers

Answer:

D. Pollution of the atmosphere

Explanation:

All the other answers would seem to only affect the designated local area. However, option D would affect both the local and global economy.

What are the products of photosynthesis?

Answers

Answer:

option C

Explanation:

Glucose and oxygen

are oxygen and glucose products in cellular respiration?

Answers

Answer:

no the oxygen and glucose are used to produce ATP in cellular respiration

5. The major functions of carbohydrates irſclude
A. Structure framework. B. Storage C. Both Aan B
D . None of these​

Answers

Answer:

D

Explanation:

used to provide energy to the body

Why do all proteins given a negative charge prior to electrophoresis?​

Answers

Answer:

The principle for native gels when Coomassie is not added to the sample is that proteins are separated by a combination of size and charge. The charge in general depends on the number of amino acid residues that bear a positive or negative charge at the pH of the gel. So if running the gel at pH from 8.3 / 8.9, Asp and Glu will be negatively charged, Lys and Arg and His will be protonated and have a positive charge. The N- terminus would have a positive charge while the C terminus would have a negative charge. There might be exceptions depending upon the micro environment of each residue. Native gels can be run at acidic pH as well, to give another way of resolving proteins. Smaller proteins migrate faster than larger proteins. Also, quaternary structure is preserved, so a dimer will run as a dimer so the percentage of total acrylamide monomer used is usually lower than what is used for SDS-PAGE, e.g. 7.5% acrylamide

Hemophilia is an X-linked recessive condition in which blood does not clot properly. Queen Victoria of England had one allele for hemophilia. Most of her male descendants had the disorder, but few females had it. Why did hemophilia occur more frequently in Queen Victoria’s male descendants?

Answers

Answer:

Because hemophilia is an X-linked recessive condition.

Explanation:

As the problem states, hemophilia is an X-linked recessive condition.

Meaning that in Queen Victoria's female descendants (coded XX) which inherited the Queen's one allele, for hemophilia to appear in them it would be necessary to inherit another hemophillia-carrying allele from the father.The Queen's male descendants (coded XY) would always manifest hemophilia if they inherited the Queen's hemophilia allele, as they possesed only one X gene.



1. Explain the relationship between the terms species and organism.

Answers

Answer:

Organism: An individual living thing

Species: A group of any given organism; a group of many individual living things

A species is defined as the group of organisms in which individuals can reproduce their progeny.

What is Species?

A species is defined as the basic unit of classification. This is also taxonomic rank of an organism, as well as a unit of biodiversity.  These are the group of organisms which can reproduce with one another in nature and produce fertile offspring.

Species can be divided further on the basis of concept like

1. Typological or Essentialist Species Concept

2. Nominalistic Species Concept

3. Biological Species Concept

4. Evolutionary Species Concept

The species designation which originated in taxonomy, where the species is the basic unit of taxonomy is recognized by the International Commission on Zoological Nomenclature. Every species is have a standard two-part name of genus and species.

Thus, a species is defined as the group of organisms in which individuals can reproduce their progeny.

Learn more about Species, here:

https://brainly.com/question/13258090

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lab reports of onion cell

Answers

Answer:

you gotta show the onion cell if you want this to be answered

explain what it means to view something from a frae of reference. provide an example that illustrate your explanation.

Answers

Answer:

ex. where you are standing now

a perspective that one uses to determine if an object is moving.

Explanation:

in physics, a frame of reference, or reference frame, is a perspective that one uses to determine if an object is moving. ... For example, when you see a ball roll down a street, you can tell the ball is moving because the frame of reference is the streets, whatever may be on the side of the roads, or the Earth.

wikipedia

Select all of the characteristic monosaccharide features that are absent in this molecule: H O H CO о -C-H H-C -O CH H-C- -O H H-C-H H​

Answers

Answer:

Carboxyl functional group.

Explanation:

Carboxyl functional group is the feature or characteristic which us absent in the monosaccharide. The carboxyl group is an organic, functional group comprising of a carbon atom which is double-bonded to an oxygen atom and have singly bond with a hydroxyl group. In other words we can say that it is a carbonyl group (C=O) that has a hydroxyl group (O-H) which is attached to the carbon atom.

The scientists mapping the SNPs in the human genome noticed that groups of SNPs tended to be inherited together, in blocks known as haplotypes, ranging in length from 5,000 to 200,000 base pairs. There are as few as four or five commonly occurring combinations of SNPs per haplotype. Integrating what you've learned throughout this chapter and this unit, propose an explanation for this observation.

Answers

Answer:

SNPs have shown that only 0.1 % of DNA sequences are different in the human genome between different individuals, thereby all the inherited phenotypic variation observed in our species is associated with only 0.1 % of differences at the genome level  

Explanation:

Haplotypes are block-like sequences of DNA that are inherited together due to low recombination rates. Moreover, single-nucleotide polymorphism (SNP) mapping is a very useful methodology used to map the site of SNP mutations (i.e., SNP variants). In this regard, it has been observed that there are approximately 10 million common SNPs in the human genome. These SNPs contribute to the wide range of phenotypic variation observed in human populations for different traits (e.g., eye color, hair, weight, height, etc). Moreover, researchers have determined that SNPs can be clustered into haplotypes, thereby haplotypes can be accurately sampled by as few as approx. 300,000 selected SNPs, which are sufficient to represent all of the genetic variation across different human genomes.

3a) label the structure of bacterium below i-vi​

Answers

Answer:

I. Cell capsule

II. Cell wall

III. Plasma membrane

IV. Nucleoid

V. Cytoplasm

Explanation:

In the structure of bacterium, I represent Cell capsule which is the outer covering of bacterium cell, II is the Cell wall that is located after the cell capsule. III is the Plasma membrane which is also called cell membrane which is the second boundary of cell. IV represents Nucleoid which like nucleus having genetic material, V is Cytoplasm that is responsible for the transportation medium for various nutrients..

Using the organisms you identified in part B, create a food web for the ecosystem you chose. Use this sample food web for reference, although your food web will contain fewer organisms. Note that your food web does not have to include images, but you may include them if you choose. However, be sure to include arrows to indicate the direction of energy flow in your food web. Design your food web using any method listed below:

Answers

Unfortunately you did not introduce the organisms identified in part B, as the question shows. This makes it impossible for me to answer this question, but I will try and help as best I can.

In the figure attached to the question below, it is possible to see an example of a food web and the arrows that indicate the direction of the energy flow within this food web.

In this sense, we can determine that a food web is the set of food chains that complete and mix. A food chain shows how living organisms organize themselves so that one feeds on the other, whereas in the food web, this food chain is shown in a more realistic way, as it shows how food chains mix and interact within the ecosystem, as they do not there are food chains isolated in nature.

Answer:

I did Lake Tahoe. Feel free to use this image!

Explanation:

The Big Bang is an idea that states that billions of years ago the universe began in a huge expansion of matter. This
idea has come about through numerous experiments performed by scientists including Edwin Hubble, Albert
Einstein, and Robert Wilson, all of whom revised and added to it over time The Big Bang has not yet been proven as
fact
The Big Bang can be best described as a(n)
experiment
hypothesis
theory
law

Answers

Answer:

The Big Bang theory is the prevailing cosmological model explaining the existence of the observable universe from the earliest known periods through its subsequent large-scale evolution. The model describes how the universe expanded from an initial state of high density and temperature,and offers a comprehensive explanation for a broad range of observed phenomena, including the abundance of light elements, the cosmic microwave background (CMB) radiation, and large-scale structure.

Crucially, the theory is compatible with Hubble–Lemaître law—the observation that the farther away a galaxy is, the faster it is moving away from Earth. Extrapolating this cosmic expansion backwards in time using the known laws of physics, the theory describes an increasingly concentrated cosmos preceded by a singularity in which space and time lose meaning (typically named "the Big Bang singularity"). Detailed measurements of the expansion rate of the universe place the Big Bang singularity at around 13.8 billion years ago, which is thus considered the age of the universe.

After its initial expansion, an event that is by itself often called "the Big Bang", the universe cooled sufficiently to allow the formation of subatomic particles, and later atoms. Giant clouds of these primordial elements—mostly hydrogen, with some helium and lithium—later coalesced through gravity, forming early stars and galaxies, the descendants of which are visible today. Besides these primordial building materials, astronomers observe the gravitational effects of an unknown dark matter surrounding galaxies. Most of the gravitational potential in the universe seems to be in this form, and the Big Bang theory and various observations indicate that this excess gravitational potential is not created by baryonic matter, such as normal atoms. Measurements of the redshifts of supernovae indicate that the expansion of the universe is accelerating, an observation attributed to dark energy's existence.

Georges Lemaître first noted in 1927 that an expanding universe could be traced back in time to an originating single point, which he called the "primeval atom". Edwin Hubble confirmed through analysis of galactic redshifts in 1929 that galaxies are indeed drifting apart; this is important observational evidence for an expanding universe. For several decades, the scientific community was divided between supporters of the Big Bang and the rival steady-state model which both offered explanations for the observed expansion, but the steady-state model stipulated an eternal universe in contrast to the Big Bang's finite age. In 1964, the CMB was discovered, which convinced many cosmologists that the steady-state theory was falsified, since, unlike the steady-state theory, the hot Big Bang predicted a uniform background radiation throughout the universe caused by the high temperatures and densities in the distant past. A wide range of empirical evidence strongly favors the Big Bang, which is now essentially universally accepted.

Explanation:

Answer:

Explanation:

its a theory

If the lymph system did not do its job, what would be one of the consequences?

Answers

Answer:

"*Because the lymphatic system collects excess tissue fluid, if it were not working, swelling (edema) would occur in the tissues. The thymus cleanses the blood from the cardiovascular system of cellular debris and bacteria."

in what ways are forest non-renewable? in what ways can they be renewable resources?​

Answers

Answer:

A renewable resource is a natural material that is replenished in the environment through natural processes. These materials can be used indefinitely, as long as they are not consumed at a rate faster than they can be restored.

PLEASEEEE ANSWER ASAPPP WILL GIVE BRAINLIESTTT

Identify the number of electrons each of the following atoms needs to gain or lose to have a stable outer electron configuration: Sodium(Na), Sulfur(S), Strontium(Sr)

Answers

Answer:

Sodium: +8

Sulfur: +2

Strontium: -2

Explain the cause of circulatory in frog

Answers

Answer:

In the frog, Rana, venous blood is driven into the right atrium of the heart by contraction of the sinus venosus, and it flows into the left atrium from the lungs. A wave of contraction then spreads over the whole atrium and drives blood into the ventricle, where blood from the two sources tends to remain separate.

Explanation:

hope it will help u

ssons
sts & Quizzes
essages
What mistake(s) can you identify in this graph?
1. Poor scale, wasted space
II. No units for independent variable
III. No units for dependent variable
IV. One axis uses decimals and the other does not.
140
astant Teacher
Sradebook
120
100
80
volume of gas produced in 1 minute
60
40
20
o
0.0
3.0
0.5 1.0 1.5 2.0 2.5
acid concentration (M)
Type here to search
o
HE

Answers

Answer:

I. Poor scale, wasted space

III. No units for dependent variable

Explanation:

Given

See attachment for graph

Required

Identify the mistakes

The mistakes are

(I) Poor scale

The unused space on the vertical axis is much. A better scale would have reduced the amount of unused space.

(II) There is a unit (1 minute) in the independent variable; so, this is not a mistake

(III) No unit on the dependent variable

Yes, this is part of the mistake, as there is no units on the x-axis

(IV) Decimals

This is not a compulsory requirement of plotting graphs; so, this is also not a mistake

Hence,

Hence (I) and (III) are mistakes on the graph

Answer:

II

Explanation:

Cuz it is

Describe how and where viruses reproduce and the function of RNA and DNA in this process.

Answers

Answer:

Using the host's cellular metabolism, the viral DNA begins to replicate and form proteins. Then fully formed viruses assemble. These viruses break, or lyse, the cell and spread to other cells to continue the cycle. Like the lytic cycle, in the lysogenic cycle the virus attaches to the host cell and injects its DNA.

1. The large cell is called secondary oocyte and the small one is called _______.

2. What parts of organ that located at the right side of upper abdomen?

3. It is yellowish gland about 18cm long and 4 cm wide.

4. The ____________ provides the oxygen necessary for cells to metabolize.

5. The _____________ moves the oxygen around the body and to the cells.

6. It a specialized sub-unit within a cell that has a specific function such as; mitochondrion, golgi bodies, lysosome, vacuole, etc.

7. _________ are the tiny building blocks of our tissues and organs.

8. In what process where sex cells undergo meiosis to form sperm cells (spermatogenesis) in male and egg cells (oogenesis) in female.

9. This is a production of sperm by the process of meiosis.

10. It is process of producing egg cells by means of meiosis.​

Answers

1. Polar body
2. Lungs, stomach,heart, thymus, spleen, brain and etc
3.liver
4. Rbc
5. Blood
6. Cytoplasm
7. Cells
8. Gametogenesis
9. Spermatogenesis
10. Oogenesis

the value 10.00 has sigificant figuers

Answers

Answer:

1.e 1,0,0,0

Explanation:

it's just that

i.Name two heart diseases in humans.


ii.State three causes of heart diseases.​

Answers

Answer:

Arrhythmia

Atherosclerosis

Common causes of heart diseases

Diabetes.

Drug abuse.

Excessive use of alcohol or caffeine.

High blood pressure.

There have been a number of studies indicating that schizophrenia is a complex genetic disorder. Which of the following observations are most consistent with this hypothesis?
1. Siblings of individuals with schizophrenia have an elevated risk of developing schizophrenia.
2. In monozygotic twins, if one twin has schizophrenia, it is very rare that the other is affected.
3. Malnutrition in utero and certain infections may increase risk of schizophrenia.
4. Schizophrenia follows an autosomal recessive inheritance pattern.

Answers

Answer:

1. and 4.

Explanation:

1 explains that siblings may have it since they have the same genetics and 4 explains that it is a autosomal recessive trait and follows a pattern genetically.

Write on the formation of fruits and seeds as well as alternation of generation in bryophytes.​

Answers

Answer:

Fruit and seeds formation takes place due to the diffusion and fertilization of ovary.

Explanation:

After the process of pollination and fertilization the seed are forced by the fertilized ovule that is divided by the meiosis and formation of seeds completes the processes and has the potential of developing into a new plant under the optimal conditions. The ovary of the plant develops into fruits and ovules develop into seeds. Seed formation competes for the reproduction of plants. Bryophytes are small noon vascular flowering plants such as mosses.

In a certain population, the allele causing sickle cell anemia has a frequency of 0.2. If the population is in genetic equilibrium for this allele, what fraction of the population would be heterozygous for this gene

Answers

Answer:  

32% population would be heterozygous for this gene.

Explanation:

Due to technical problems, you will find the complete explanation in the attached files

Other Questions
Please answer this question Data representation and interactivity are important aspects of data visualization.a. Trueb. False the value of (-15/23)+(+30/-46) is ---------. Help please I dont get may I please have help with this Find the average variable cost for producing 18 sneakers. Round your answer to the nearest hundredth. What is Victors main conflict in the story? Choose the best answer. If one table and two lamps cost $88, and twotables and three lamps cost $153, how muchdoes a lamp cost? Suppose that the consensus forecast of security analysts of your favorite company is that earnings next year will be $5.00 per share. The company plows back 50% of its earnings and if the Chief Financial Officer (CFO) estimates that the company's return on equity (ROE) is 16%. Assuming the plowback ratio and the ROE are expected to remain constant forever:If you believe that the company's required rate of return is 10%, what is your estimate of the price of the company's stock? After the earth will destroyed then what will be the next generation Highlight the adjectives in the following paragraph. According to the ancient Greeks, eyes could reveal a personality. The Greeks compared the eyes of people to the eyes of various animals. Then they attributed the personality traits of those animals to people. Lion eyes, for example, are almond-like. In a person they signified a sense of fairness, a sense of justice, and leadership skills. Money eyes are small in relation to the face, but they have large irises. The Greeks thought that people with these eyes were unpredictable and shy. Elephant eyes are long and narrow with several folds of skin on the upper and lower eyelids. People with elephant eyes, it was believed, could handle difficult problems and solve them in a thoughtful, methodical manner. This unusual list of eye types also included the eyes of sheep, horses, wolves, hogs, snakes, and fish. Most historians tend to agree that the term 'feudalism' a. should be restricted to European history. b. can be a useful tool for the comparative study of societies. c. should be restricted to Japanese history. d. should be restricted to European and Chinese history. e. is outmoded and does not reflect the modern comparative emphasis in history. I need help on my math!!!!!!! What is the value of -97-7 when /= 2?-25-181145 Penelope withdraws $4,115.23 at the end of a five-year investment yielding 4% interest, compounded annually. How much did Penelope originally deposit which of these is a good communication strategy help avoid alcohol, tobacco, and any other drugs CAN SOMEONE HELP ME AND EXPLAIN ASAP THANKS ________ psychology is based on the premise that to understand a person, you must understand his or her unique view of reality. the line segment AB is rotated through 90 clockwise about the point C. the coordinates of A', the image of A, are When the Supreme Court rules on a constitutional issue, that judgment is virtually final; its decisions can be altered only by the rarely used procedure of constitutional amendment or by a new ruling of the Court.