It has been observed that diseases caused by repeat expansions are the result of trinucleotide repeats rather than smaller or larger repeat lengths. If non-trinucleotide repeat expansions were present in the coding region of a gene, which type of mutation would you expect to be the most likely

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Answer 1

Repeat expansions are known to cause several genetic diseases, including Huntington's disease, Fragile X syndrome, and Spinocerebellar ataxia. These repeat expansions occur due to the expansion of a trinucleotide or other repetitive DNA sequence within the gene's coding region.


It has been observed that trinucleotide repeat expansions are more likely to cause diseases compared to smaller or larger repeat lengths.


In the case of non-trinucleotide repeat expansions in the coding region of a gene, the most likely type of mutation would be frameshift mutations. Frameshift mutations occur due to the insertion or deletion of a nucleotide, which can change the reading frame of the gene and result in a completely different amino acid sequence being produced. This can lead to a non-functional protein being produced or even cause the production of a protein with toxic properties that can cause disease.

In conclusion, while trinucleotide repeat expansions are more commonly associated with genetic diseases, non-trinucleotide repeat expansions can also lead to diseases through the occurrence of frameshift mutations. The understanding of these genetic mechanisms is crucial in the development of treatments and potential cures for genetic diseases caused by repeat expansions.

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Related Questions

Humoral immunity is mediated by: Group of answer choices natural killer cells. T lymphocytes (T cells). B lymphocytes (B cells). neutrophils NAT 302

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Humoral immunity is mediated by B lymphocytes (B cells).

These cells produce and secrete antibodies, which are proteins that recognize and bind to specific antigens (molecules that elicit an immune response). B cells can recognize antigens directly or with the help of T cells. Once activated, B cells differentiate into plasma cells that produce large amounts of antibodies, which can neutralize pathogens or target them for destruction by other immune cells. Humoral immunity is important for fighting extracellular pathogens, such as bacteria and viruses, that are circulating in the bloodstream or other body fluids. T lymphocytes, on the other hand, mediate cell-mediated immunity, which is important for eliminating intracellular pathogens, such as viruses and some bacteria.

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Which of the following cell types is responsible for mediating humoral immunity?

A) Natural killer cells

B) T lymphocytes (T cells)

C) B lymphocytes (B cells)

D) Neutrophils

Adjusting and incorporating the use of a substance into the normal functioning of the body's tissues is known as _____.

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Adjusting and incorporating the use of a substance into the normal functioning of the body's tissues is known as Metabolic adaptation.

Metabolic adaptation is the process of adjusting and incorporating the use of a substance into the normal functioning of the body’s tissues. This process is necessary for the body to become accustomed to the presence of a new substance, whether it is from a medication, a food, or an environmental toxin.

As the substance is broken down, the body adjusts its metabolic pathways to accommodate the influx of the new substance and its breakdown products. This process of adaptation helps the body to efficiently process the substance, as well as to minimize any potential harm that it may cause.

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In humans, the gene for Huntington's disease contains a triplet sequence repeat, which is expanded in the disease allele, relative to the normal allele. This type of change in DNA is called a ______.

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The type of change in DNA that is responsible for the expansion of triplet sequence repeat in the gene for Huntington's disease is called a "repeat expansion mutation".

Repeat expansions occur when the number of copies of a particular DNA sequence is increased beyond a certain threshold. In the case of Huntington's disease, the normal allele contains a repeat sequence of up to 35 copies, while the disease allele contains an expanded repeat sequence of 36 or more copies. This expansion leads to the production of a mutated protein that is toxic to cells, ultimately resulting in the symptoms of the disease. Repeat expansions are also responsible for other genetic disorders, such as Fragile X syndrome and Myotonic dystrophy.

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[22] Discuss what your analysis above indicates about the applicability of the Hardy-Weinberg criteria to this population. Which assumptions, if any, of the Hardy-Weinberg criteria are violated

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The Hardy-Weinberg principle is a mathematical model used to predict the genotype frequencies of a population under certain assumptions.

The criteria that must be met for a population to be in Hardy-Weinberg equilibrium include no mutations, no migration, random mating, no natural selection, and large population size.

After analyzing the population in question, it appears that some of the assumptions of the Hardy-Weinberg criteria have been violated. Specifically, there seems to be a deviation from the expected genotype frequencies, indicating that there may be some form of selection occurring in the population. This could be due to factors such as environmental pressures, genetic drift, or migration.

Overall, while the Hardy-Weinberg principle can be a useful tool for predicting genotype frequencies in a population, it is important to keep in mind that it is based on a set of assumptions that may not always be met in reality. Therefore, caution should be exercised when applying this model to real-world populations. Additionally, it is possible that there are mutations occurring in the population, which would also violate the Hardy-Weinberg criteria. However, more research would need to be done to confirm this.

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You did an environmental swab of your front door handle, your bathroom faucet, and your car steering wheel. Write a Hypothesis (in the correct format) that predicts which of the three environments would most likely show a positive result on the MacConkey agar plate

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Due to the presence of fecal bacteria, the bathroom tap is most likely to produce a positive result on the MacConkey agar plate.

Gram-negative bacteria are typically isolated and differentiated using the selective and differentiating MacConkey agar plate. It comprises lactose and neutral red, which enable the differentiation of lactose-fermenting bacteria, as well as bile salts and crystal violet, which prevent the growth of Gram-positive bacteria.

Bathroom faucets are frequently touched with unclean hands and are frequently located near toilets, making them potential fecal contamination sites. Fecal bacteria that are known lactose fermenters, such as Escherichia coli and Klebsiella pneumonia, would show up as pink or red colonies on the MacConkey agar plate.

On the other hand, because they are not generally connected with fecal contamination, the front door handle and the car steering wheel are less likely to yield a positive result on the MacConkey agar plate. Environmental contamination, however, could come from things like soil, animals, or other people's hands.

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The bathroom faucet is most likely to show a positive result on the MacConkey agar plate.

MacConkey agar is a selective and differential medium commonly used to isolate and differentiate Gram-negative bacteria, particularly those that ferment lactose. The agar plate contains crystal violet and bile salts, which inhibit the growth of Gram-positive bacteria and many Gram-negative bacteria that do not ferment lactose.

Bathroom faucets are frequently touched by human hands, which may carry bacteria from the skin or other sources. Additionally, bathrooms are typically humid environments, which can promote bacterial growth.

Therefore, it is likely that the bathroom faucet has a higher concentration of bacteria that can ferment lactose and grow on MacConkey agar compared to the front door handle or the car steering wheel.

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What do the two daughter cells generated by the first asymmetric division of the plant zygote become

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The two daughter cells generated by the first asymmetric division of the plant zygote are known as the root and shoot apical meristems. The root apical meristem is located at the base of the root and is responsible for the development of the root system.

This includes the primary and lateral roots, as well as the root hairs. The shoot apical meristem is located at the tip of the shoot and is responsible for the growth of the stem, leaves, and flowers. This is where the majority of the plant’s growth occurs.

As the plant grows, the root and shoot apical meristems divide, producing new cells that differentiate into the structures that make up the root and shoot systems. This cell division and differentiation is what allows the plant to achieve its mature form.

Beyond the primary root and shoot systems, the shoot apical meristem also produces lateral buds and other structures that are responsible for the formation of fruits and flowers. Thus, the two daughter cells generated by the first asymmetric division of the plant zygote can be seen as the source of all of the growth and development of the plant.

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a. in homozygous ey loss-of-function mutants, eyes do not develop normally. does this information alone prove that ey is the "master regulator" in eye development? why or why not? (2-3 sentences)

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The information alone does not prove that eye is the "master regulator" in eye development.

Other genes and factors could also play a role in eye development, and the loss-of-function mutation in eye could be one of many contributing factors. Additional experiments and research would be necessary to determine if eye is the primary regulator of eye development.

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True or False: Growing axons follow the routes of axons already established by pioneer growth cones. They follow these first axons by a process known as fasciculation.

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True. Growing axons follow the routes of axons already established by pioneer growth cones through a process known as fasciculation.

Fasciculation is the process by which growing axons move in close proximity to one another, gradually aligning themselves with the established path of the pioneer growth cone. This allows the growing axon to navigate through the extracellular matrix and find its way to its target destination. Fasciculation is mediated by the interaction of the growth cone and the extracellular matrix, as well as by the guidance of chemotactic gradients and adhesion molecules.  

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The given statement "Growing axons follow the routes of axons already established by pioneer growth cones. They follow these first axons by a process known as fasciculation" is true.

During the development of the nervous system, pioneer growth cones are the first axons to navigate through the developing tissue to their target destination. These growth cones secrete chemical signals that attract or repel other growth cones and growing axons. Once a pioneer growth cone has reached its target, it establishes a pathway for other axons to follow.

Growing axons then follow the established pathway through a process called fasciculation, in which they cluster together and follow the same route as the pioneer axon. This helps to ensure that the nervous system develops in an organized and functional manner.

Therefore, the given statement is true.

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Human interference with the reproduction of another species, with the result that specific plants and animals become more useful to people and dependent on them is called Question 3 options: domestication sedentism niche construction dependency

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Domestication is the term for human intervention in the reproduction of another species that results in certain plants and animals being more dependent on humans and helpful to them. Here option A is the correct answer.

Domestication refers to the process by which humans selectively breed plants and animals for desirable traits, such as increased yield or docility, and thereby create populations that are dependent on humans for their survival and reproduction. Domesticated species differ from their wild ancestors in various ways, including morphology, behavior, and genetics.

Domestication has been a crucial factor in the development of human societies, as it has allowed humans to secure a reliable source of food, fiber, and labor. Domesticated plants and animals have been selectively bred and managed by humans for thousands of years, leading to the development of new and improved crop varieties and livestock breeds.

However, domestication also has its drawbacks. Domesticated populations can be vulnerable to disease, predation, and environmental changes, and they often require intensive management to thrive.

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Complete question:

Human interference with the reproduction of another species, with the result that specific plants and animals become more useful to people and dependent on them is called

a) Domestication

b) Sedentism

c) Niche construction

d) Dependency

In the human body, the oxidation of glucose produces sufficient free energy to drive the conversion of biomolecule ADP into ATP, a nonspontaneous process. This is an example of ______, where one step supplies enough free energy for another to occur.\

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The given scenario is an example of coupling, a phenomenon where an energetically favorable (spontaneous) reaction is paired with an unfavorable (nonspontaneous) reaction to drive the latter forward.

In this case, the oxidation of glucose releases a large amount of free energy, which is then utilized to drive the conversion of ADP to ATP. ATP is a biomolecule that stores and transports energy within the cells, and its synthesis from ADP requires an input of energy. Oxidation is a chemical process that involves the loss of electrons by a substance. In the human body, glucose undergoes oxidation through a series of reactions, which ultimately results in the production of ATP. This process is essential for providing energy to the cells and maintaining their functions. Biomolecules are organic molecules that are essential for life processes.

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rue or false: Because epigenetics refers to heritable changes in gene expression, all epigenetic changes are examples of transgenerational epigenetic inheritance.

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Because epigenetics refers to heritable changes in gene expression, all epigenetic changes are examples of transgenerational epigenetic inheritance is false.

Although epigenetics can refer to heritable changes in gene expression, not all epigenetic changes are examples of transgenerational epigenetic inheritance.

Epigenetic changes can occur in response to environmental factors, such as diet or stress, and may not be passed down through generations. Transgenerational epigenetic inheritance refers specifically to epigenetic changes that are passed down from one generation to the next, affecting gene expression in offspring.

The study of heritable changes in gene expression that do not involve changes to the underlying DNA sequence is known as epigenetics .

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A Gram-positive rod found in the Low G C group, ________, is a frequent contaminant of milk and meat (even under refrigeration) and an opportunistic pathogen of the immunocompromised.

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The Gram-positive rod found in the Low G C group, Listeria monocytogenes, is a frequent contaminant of milk and meat, even under refrigeration. It is also an opportunistic pathogen of the immunocompromised.

A Gram-positive rod found in the Low G C group that is a frequent contaminant of milk and meat and an opportunistic pathogen of the immunocompromised is Listeria monocytogenes.

Listeria monocytogenes is a foodborne pathogen that can cause listeriosis, a serious infection that can lead to meningitis, sepsis, and death, particularly in pregnant women, elderly individuals, and people with weakened immune systems.

Listeria monocytogenes is unique among foodborne pathogens in its ability to grow at refrigeration temperatures, allowing it to survive and multiply in refrigerated foods. It can also form biofilms, which can protect it from cleaning and disinfection efforts.

Control of Listeria monocytogenes in food processing facilities is critical to prevent contamination of food products and subsequent illness in consumers.

This involves strict sanitation procedures and testing of food and environmental samples for the presence of bacteria.

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Putting an antibiotic resistance gene in a recombinant plasmid used for genetic engineering makes: Group of answer choices replica plating possible direct selection possible the recombinant cell dangerous the recombinant cell unable to survive

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Putting an antibiotic resistance gene in a recombinant plasmid used for genetic engineering makes direct selection possible. The correct answer is B.

The antibiotic resistance gene provides a selectable marker that allows researchers to easily identify cells that have taken up the recombinant plasmid and have been successfully transformed.

Direct selection is a process by which cells that have been transformed with the recombinant plasmid can be selected for and grown directly on agar plates containing the antibiotic to which the plasmid provides resistance.

Any cells that have not taken up the plasmid and do not contain the antibiotic resistance gene will be unable to survive in the presence of the antibiotic, while cells that have taken up the plasmid and contain the resistance gene will be able to grow and form colonies on the plate.

This process allows for easy identification and isolation of cells that have taken up the recombinant plasmid, which can then be used for further analysis or genetic engineering.

By including an antibiotic-resistance gene in the recombinant plasmid, researchers can also ensure that the cells they are working with have successfully taken up the plasmid and contain the desired genetic material. Therefore, the correct answer is B.

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Question:

Putting an antibiotic resistance gene in a recombinant plasmid used for genetic engineering makes:

Group of answer choices

A) replica plating possible

B)direct selection possible

C)the recombinant cell dangerous

D)the recombinant cell unable to survive

The pancreas is an accessory gland that contributes to digestion by secreting enzymes into the small intestine. Therefore, the pancreas is involved in ____________ digestion.

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The pancreas is involved in enzymatic digestion. As an accessory gland, the pancreas plays a vital role in the digestive system by producing and releasing enzymes that help break down food in the small intestine.

These enzymes include amylase, which breaks down carbohydrates, lipase, which breaks down fats, and proteases, which break down proteins. The pancreas also secretes bicarbonate, which neutralizes stomach acid and creates a more optimal environment for these enzymes to function. Overall, the pancreas contributes significantly to the process of enzymatic digestion, ensuring that nutrients from food can be effectively absorbed and utilized by the body.

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Which of the protein complexes listed above are involved in actively pumping protons into the intermembrane space of the mitochondria

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The protein complex involved in actively pumping protons into the intermembrane space of the mitochondria is called the electron transport chain or the respiratory chain.

Specifically, proton pumping occurs during the oxidation of NADH and FADH2 by Complex I (NADH-ubiquinone oxidoreductase) and Complex II (succinate-ubiquinone oxidoreductase) respectively. During electron transport, the respiratory chain complexes, including Complex I, Complex III (ubiquinol-cytochrome c oxidoreductase), and Complex IV (cytochrome c oxidase), transport protons across the inner mitochondrial membrane from the matrix to the intermembrane space. This generates an electrochemical gradient, with a higher concentration of protons in the intermembrane space than in the matrix, which is utilized by ATP synthase to generate ATP via oxidative phosphorylation.

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How is the primary transcript produced by a prokaryotic cell different from that produced by a eukaryotic cell

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the primary transcripts produced by prokaryotic cells differ from those produced by eukaryotic cells in their location of production, gene content, and the processing they undergo.

you understand the differences between the primary transcripts produced by prokaryotic and eukaryotic cells.

1. Prokaryotic cells do not have a nucleus, while eukaryotic cells do. In prokaryotic cells, the primary transcript is produced directly in the cytoplasm, while in eukaryotic cells, it is produced in the nucleus.

2. Prokaryotic primary transcripts often contain multiple genes in a single mRNA molecule called polycistronic mRNA, whereas eukaryotic primary transcripts are typically monocistronic, containing only one gene per mRNA molecule.

3. In eukaryotic cells, the primary transcript undergoes processing, including the addition of a 5' cap and a poly-A tail, as well as intron splicing. Prokaryotic primary transcripts do not undergo these modifications.

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Most calcium in the body is located in __________. intracellular storage organelles blood plasma and other extracellular fluid cytoplasm the skeleton

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Most calcium in the body is located in the skeleton, option D is correct.

Calcium is an important mineral in the human body, serving a variety of functions including bone formation, muscle contraction, and nerve function. The majority of calcium in the body, approximately 99%, is stored in the bones and teeth.

This is important for maintaining the structural integrity of the skeletal system and for providing a reservoir of calcium that can be mobilized when needed for other functions. The remaining 1% of calcium is found in other areas of the body such as the blood, muscles, and intracellular storage organelles.

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The complete question is:

Most calcium in the body is located in __________.

A. intracellular storage

B. organelles

C. blood plasma and other extracellular fluid

D. cytoplasm

E. skeleton

Quizlet An adjuvant enhances the effectiveness of vaccines by inducing the expression of __________ on __________. Select one: a. co-stimulatory molecules; dendritic cells b. CD28; macrophages c. MHC class II molecules; T cells d. T-cell receptor; T cells e. immunoreceptor tyrosine-based activation motifs; dendritic cells

Answers

An adjuvant is an agent that enhances the effectiveness of a vaccine. It works by inducing the expression of certain molecules, such as co-stimulatory molecules, CD28, MHC class II molecules, T-cell receptor, and immunoreceptor tyrosine-based activation motifs, on dendritic cells and macrophages.

Here, all the options are correct.

These molecules can strengthen the immune response by stimulating the production of cytokines, a type of signaling molecule that helps coordinate the immune response. By activating these molecules, adjuvants help the body recognize and respond to the antigens in a vaccine, making it more effective.

Adjuvants can also increase the duration of immunity when a vaccine is given. Overall, adjuvants are an important tool for improving the effectiveness of vaccines.

Therefore, all the options are correct.

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A man and a woman are both carriers for two autosomal recessive disorders, PKU (chromosome 12) and cystic fibrosis (chromosome 7). If they have a daughter, what is the probability that she will have PKU and CF

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Autosomal recessive disorders like PKU and cystic fibrosis require two copies of the mutated gene—one from each parent—to manifest.

In the event that you are brought into the world to guardians who both convey a similar autosomal latent quality, you have a 25% (1 of every 4) opportunity of acquiring the unusual quality from the two guardians and fostering the sickness. There is a 50% (or 1 in 2) chance that you will inherit one abnormal gene.

Recessive autosomal inheritance: A carrier (two unaffected individuals with one copy of the altered gene for an autosomal recessive disorder) has a 25% chance of having a child with the disorder with each pregnancy.

Two altered genes, also known as mutations, are passed down through the family to cause an autosomal recessive disorder. Each parent provides you with one. Their well-being is seldom impacted on the grounds that they have just a single changed quality. There is a 25% chance that a child with two unaffected genes will be born to two carriers.

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An inhibitor that binds only to the ES complex and not free enzyme is known as a(n) __________ inhibitor.

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An inhibitor that binds only to the ES complex (enzyme-substrate complex) and not the free enzyme is known as an uncompetitive inhibitor.

It works by competing with the substrate for the active site of the enzyme, so that the substrate cannot bind and the enzyme cannot catalyze the reaction. This type of inhibitor works because the enzyme-inhibitor complex is less stable than the enzyme-substrate complex, and so the enzyme-inhibitor complex dissociates more quickly than the enzyme-substrate complex. This means that the enzyme cannot catalyze the reaction, as the substrate cannot bind. Competitive inhibitors can be reversible or irreversible, depending on their chemical structure.

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a)She should grow Long day variety because in late spring and early summer the day length is more. b)Ripening fruits after harvest : Spraying of ethylene.

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a) She should grow a long day variety because in late spring and early summer, the day length is longer. b) Ripening fruits after harvest can be achieved by spraying ethylene.

a) Long day variety plants require more hours of daylight to grow and develop optimally. Late spring and early summer provide longer days with more sunlight, which is suitable for long day variety plants.

Growing these plants during this period will help them thrive and produce better yields.

b) Ethylene is a natural plant hormone that plays a crucial role in fruit ripening. Spraying fruits with ethylene after harvest can speed up the ripening process, making the fruits ready for consumption or sale more quickly.

This technique is commonly used in the agriculture industry to control the ripening process and ensure consistent product quality.

To achieve the best results, it is recommended to grow long day variety plants in late spring and early summer when there is ample sunlight, and to use ethylene spraying to expedite the ripening of fruits after harvest.

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Lipogenesis occurs when ________. A) there is a shortage of fatty acids B) glucose levels drop slightly C) excess proteins are transported through the cell membrane D) cellular ATP and glucose levels are high

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Lipogenesis occurs when cellular ATP and glucose levels are high. So, option D is the correct answer.

Lipogenesis involves the conversion of glucose or other substrates such as amino acids into fatty acids, which are then stored in adipose tissue for future energy use. Insulin is the hormone responsible for stimulating lipogenesis by increasing glucose uptake into cells and activating key enzymes involved in fatty acid synthesis. Lipogenesis can also occur in response to a high carbohydrate or calorie-rich diet, which can lead to the accumulation of excess fat in the body.

However, lipogenesis is usually inhibited when there is a shortage of fatty acids or when glucose levels drop, as the body switches to alternative energy sources such as ketones. Understanding the factors that regulate lipogenesis is important for maintaining metabolic homeostasis and preventing metabolic disorders such as obesity and diabetes.

Therefore, option D is the correct answer.

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Explain how the central and the peripheral nervous system work together to allow you to pick up a glass of water. Mention muscles of the forearm in your answer.

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The central nervous system (CNS) and the peripheral nervous system (PNS) work together to allow a person to pick up a glass of water. The CNS is responsible for sending signals from the brain to the muscles in the forearm.

The PNS then carries the signals from the CNS to the muscle fibers and instructs them to contract. This causes the muscles of the forearm to flex, resulting in the arm bending at the elbow and allowing the person to pick up the glass of water.

The CNS then sends another set of signals to the muscles of the forearm, instructing them to relax, allowing the person to grasp the glass of water. The CNS can also send signals to the muscles of the hand, instructing them to close and grip the glass of water.

The PNS then carries the signal to the muscles of the hand, causing them to contract and allowing the person to grasp the glass of water securely. Finally, the CNS sends a signal to the muscles of the forearm to extend, allowing the person to lift the glass of water.

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what is the function of dna polymerase iii in dna synthesis it adds new dna nucleotides to the 3' prime end of the growing dna strand

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The function of DNA polymerase III in DNA synthesis is to add new DNA nucleotides to the 3' prime end of the growing DNA strand during DNA replication.

DNA polymerase is an enzyme that is involved in the process of DNA replication, which is the process by which a cell makes a copy of its DNA. DNA polymerase adds new nucleotides to a growing DNA chain during replication. The nucleotides are added in a complementary fashion to the template strand, with the help of base pairing rules (A-T and C-G).

There are different types of DNA polymerases in cells, each with specific functions. For example, DNA polymerase III is the primary polymerase responsible for the elongation of the new DNA strand during replication, while DNA polymerase I is involved in DNA repair and removal of RNA primers during replication. DNA polymerases are critical for maintaining the accuracy and fidelity of DNA replication, as errors in replication can lead to mutations and genetic diseases.

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Which experiments in yeast would demonstrate that recombination was successful and that the desired gene was integrated into the yeast chromosome

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There are several experiments that could demonstrate the successful integration of a desired gene into the yeast chromosome through recombination. One approach would be to perform PCR analysis using primers specific to the integrated gene and the yeast chromosome.

If the desired gene is present in the yeast genome, PCR amplification products should be obtained. Another experiment would be to perform Southern blot analysis using a probe specific to the integrated gene. If successful recombination has occurred, a band corresponding to the desired gene should be observed in the Southern blot.

Additionally, phenotype analysis could be performed to confirm the expression of the integrated gene in yeast. For example, if the desired gene encodes a selectable marker, transformed yeast cells should exhibit the selectable phenotype. These experiments collectively demonstrate that the recombination was successful and that the desired gene was integrated into the yeast chromosome.

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Assume the graph below is a population of rabbits in an ecosystem over a period of 10 years.
Which of the following factors most likely cause the population level to reach carrying capacity
- Natural Disaster
-Disease
- Amount of Food
- Migration

Answers

The factor most likely causing the population level to reach carrying capacity is migration. Migration is the moment of the animal population's search for better food availabilities, and climatic conditions. The movement can be seasonal, interregional, and intercontinental.

Migration helps in finding better habitable conditions which widens their range of consumption. This leads to an increase in the population as the conditions are favorable. Resulting in reaching the maximum carrying capacity of the population in the particular habitat.

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Cardiac muscle cells are arranged in _____ bundles and wrapped around and between the heart chambers.

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Cardiac muscle cells are arranged in vertical bundles and wrap around and between the heart chambers.

This arrangement of cardiac muscle cells is crucial to the functioning of the heart, as it allows the heart to contract and relax in a coordinated manner. On the innermost layer of the heart, the cells are arranged in a spiral pattern, which helps to propel the blood through the chambers.

In the middle layer, the cells are arranged in a crisscross pattern, allowing for efficient contraction of the heart muscles. The outermost layer is arranged in vertical bundles, which allows for the efficient relaxation of the heart muscles during diastole.

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Fill in the blank question. The presence of both inherent diversity and acquired diversity is called

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The presence of both inherent diversity and acquired diversity is called intersectionality. Inherent diversity refers to the characteristics we are born with, such as race, gender, and sexual orientation. Acquired diversity, on the other hand, includes the characteristics we gain throughout our lives, such as education, language proficiency, and work experience.


The presence of both inherent diversity and acquired diversity is called "cognitive diversity." Inherent diversity refers to the differences in traits that people are born with, such as race, gender, and ethnicity. Acquired diversity involves the differences in experiences and perspectives gained throughout a person's life, such as education, skills, and work experiences. Cognitive diversity is important in organizations because it fosters a wide range of ideas and opinions, leading to better problem-solving, innovation, and adaptability. Embracing cognitive diversity can create a more inclusive and effective work environment.

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Across a normal cellular membrane, the potential is maintained with a positive charge on the outside of the cell and a negative charge on the inside of the cell. Which of the following best explains the operation of the voltage sensor in the voltage-gated sodium channel? a. Under resting cellular conditions, the voltage sensor is normally pulled to the inside of the cell due to its high arginine content b. Under resting cellular conditions, the voltage sensor is normally pulled to the outside of the cell due to its high lysine content c. When the membrane is depolarized, the voltage sensor moves towards the outside of the membrane, allowing opening of the activation gate d. Both a and c occur e. None of the above

Answers

The correct answer is c. When the membrane is depolarized, the voltage sensor moves towards the outside of the membrane, allowing opening of the activation gate.

Voltage-gated sodium channels are responsible for the rapid depolarization of the cell membrane during action potentials. These channels contain a voltage sensor that detects changes in membrane potential. The voltage sensor is composed of charged amino acids, such as arginine and lysine. During resting conditions, the voltage sensor is in a closed state and is normally pulled towards the inside of the cell due to its high arginine content. However, when the membrane is depolarized, the voltage sensor moves towards the outside of the membrane, which causes a conformational change in the channel protein, allowing opening of the activation gate. This leads to an influx of sodium ions into the cell, which further depolarizes the membrane and triggers an action potential. Therefore, option c best explains the operation of the voltage sensor in the voltage-gated sodium channel.

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The opening extending the length of the spinal cord that communicates with the ventricular system of the brain is called the ___________ ___________.

Answers

The opening extending the length of the spinal cord that communicates with the ventricular system of the brain is called the central canal.The central canal is a tiny channel that runs through the length of the spinal cord and connects with the ventricular system of the brain.

It is filled with cerebrospinal fluid (CSF) which provides nourishment and protection to the spinal cord.
The opening extending the length of the spinal cord that communicates with the ventricular system of the brain is called the central canal.

The central canal is a narrow, fluid-filled channel that runs longitudinally through the length of the spinal cord. It is lined with ependymal cells and is continuous with the ventricular system of the brain. The central canal serves as a pathway for the circulation of cerebrospinal fluid (CSF), which provides nourishment and protection for both the spinal cord and the brain. The flow of CSF within the central canal and ventricular system helps maintain the appropriate pressure and chemical environment for optimal functioning of the central nervous system.

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