individuals with marfan syndrome have a mutates gene in chromosome 15 which causes many phenotpic abnormalities such as disproportionately long arms and legs, a weakened aorta, stretch marks in skin, and poor eyesight. the pattern inheritance that would best describe this genetic disorder is

Answers

Answer 1

Answer:

It is inherited following an autosomal dominant inheritance; in this way, the risk that the child of an affected father or affected mother will have the disease is 50%.

Explanation:

Marfan syndrome is a systemic connective tissue disorder, autosomal dominant, which means that statistically the probability that a patient's children are affected by the disease is approximately 50%, it is caused by mutations in the protein of the extracellular matrix fibrillin 1. This disease mainly affects the cardiovascular, ocular and skeletal systems. The elastic fiber has the function of distension and retraction, it is part of the extracellular matrix of the tissues and is composed of elastin and a network of microfibrils that serves as a framework for the elastin deposit and the assembly of the elastic fibers. This network of microfibrils is formed by fibrillin1, which is encoded by the FBN1 gene on chromosome 15q21, the defect of which is expressed through a dominant negative effect, that is, in heterozygotes, the mutant fibrillin1 destroys the assembly of normal microfibrils, possibly , by acting with the products of the normal allele.


Related Questions

What is a marine ecosystem?

Answers

Answer:Marine ecosystems are the largest of Earth's aquatic ecosystems and are distinguished by waters that have a high salt content. These systems contrast with freshwater ecosystems, which have a lower salt content.

Explanation:

s

Answer:e a marine ecosystem is the life underwater like sea creaters ,a weed etc s

Explanation:

online defnation : Marine ecosystems are characterized by the biological community of organisms that they are associated with and their physical environment.

heres a fact Some important characteristics of the marine ecosystem are: They make up 70% of the earth’s surface. They dissolve the salts in their own waters. Supplies food for humans and generates socioeconomic benefits. They fall into the category of aquatic ecosystems

All you need is on the photo

Answers

Answer: B

Explanation:

When immigration into an area is higher than emigration out and with other factors kept constant, you will have a situation where population will increase.

This is the case in the point of the graph labelled B. We can see a rise in population so immigration must be more than emigration. In the other points, the population is reducing which means that more orca whales are leaving than coming in.

Which type of joints allows movement

Answers

Answer:

The correct answer would be - synovial joints.

Explanation:

Synovial joints are the joints that allow bones to move as these joints are able to great movement freely of the three structural joints. These joints have synovial fluid which helps and enabling the structures of the joints to move smoothly against each other.

They also called diarthroses which means freely movable. Ball and socket joints is a type of synovial joint that allows movements in all direction with help of muscles attached to it. Hip joint and Shouder joint are examples of such joint.

Answer:

Synovial joints

Explanation:

Synovial joints achieve movement at the point of contact of the articulating bones.

Synovial joints allow bones to slide past each other or to rotate around each other. This produces movements called abduction (away), adduction (towards), extension (open), flexion (close), and rotation.

Lipids commonly contain fatty acids. What are the two parts of a fatty acid? Check the correct answers below. amino group long chain of carbon and hydrogen carboxyl group R group nucleotide​

Answers

Answer:

long chain of carbon and hydrogen

carboxyl group

The correct choices are - long chain of carbon and hydrogen and carboxyl group as fatty acid have long chains of hydrocarbons with carboxyl group makes it acid.

A fatty acid is an aliphatic chain with carboxylic acid that can be either saturated or unsaturated. Fatty acids make the lipid membrane with glycerols. A fatty acid consists of

A long chain of an even number of carbon atoms and hydrogen atoms along the length of the chain at the end of the chainA carboxyl group (―COOH) at the other end.The carboxyl group makes it an acid (carboxylic acid).

Thus, the correct among the given choices are - long chain of carbon and hydrogen, a carboxyl group.

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During which step of the cell cycle does a cell get a signal to begin cell division?

Answers

Answer:

Prophase

Explanation:

Prophase is not only the first step of Mitosis and Meiosis (I and II), but it is crucial because it helps the chromatin become chromosomes, this is after Interphase where DNA replication occurs this is the signal that starts the dividing process. This phase also helps with condensing the chromosomes which acts as another signal to division because the chromosomes are prepared to be separated from one another. Spindle fibers (microtubules) are also created to get ready for separation. Now that these main things happened during Prophase, it signifies the rest of the cell and the other phases occur.

Hope this helped :)  

I need someone to answer 11

Answers

Answer:

Explanation:

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Acidity please mark brainlyiest

Genetic Engineering has many exciting benefits but also some potential risks.
True
Or false

Answers

Answer:

True

Explanation:

Answer:

True

Explanation:

Many Genetic Engineering jobs have good pay-out or help the world, but sometimes they can be dangerous.

pick 4 simple machines and explain how they are used in your everyday life

Answers

Answer:

1. Cars

Because they help me and my family get places

2. Phones

Because I think that they also help my getting u places and just for entianment or school

3. Computers

They help with school as well

4. TVs

They help with the news

Explanation:

Climatology study cumulative weather data. They analyze the average_______and average _______. Temperature,precipitation. Snow,rain. Rain,sun

Answers

Answer: temperature, precipitation

Explanation: I just took the test and got it right

How does energy move through living systems?

A. Energy can be created by organisms and can be passed on if it is not used by that organism

B. All of the energy is used up by organisms as they move, grow and reproduce so less energy is available for the next organism in the food chain

C. Energy is transformed and/or lost as heat as it passes from one organism to the next, but the total amount always stays the same

D. Energy is created during photosynthesis

Answers

Answer:energy is produced during photosynthesis. energy is used by the photosynthesiser or lost as heat, with the remainder available to the next organism in the food chain.

Explanation: self explanatory

identify the main characteristerics of cells

Answers

Answer:

mitochondria, ribosomes, nuclei, golgi bodies, cell walls, cytoplasm...

Explanation:

what molecule is energy stored in the process of respiration

Answers

Answer:

Hope the above picture might help you :)

It is ATP. Specifically, during cellular respiration, the energy stored in glucose is transferred to ATP

All you need is on the photo

Answers

Answer:

B

Explanation:

photosynthesis takes in CO2 and gives O2, so if it were photosynthesis the lines would be swapped. cellular respiration takes in O2 and expels CO2.

Answer:

B Cellular Respiration

Explanation:

In Cellular Respiration organisms use Oxygen and give out Carbon dioxide.

In Photosynthesis plants use Carbon dioxide and give out Oxygen.

What do the layers in this sedimentary rock reveal?

sedimentary rock showing lines of different colored rock formed over time
Public Domain
Question 1 options:

Why the dinosaurs all died

How the landscape changed over time

When we can expect the next earthquake

What the temperature will be in the future

Answers

Answer:

How the landscape changed over time

Explanation:

If a paramecium swims from a hypotonic to an isotonic environment, will its contractilevacuole become more active or less?

Answers

Answer:

Less.

Explanation:

Its contractile vacuole become less active because of the same concentration of water in both the body and outside environment. Contractile vacuole is responsible for the removal of excess liquid with the help of contraction. In isotonic environment, there is no flow water occur inside or outside of the cell due to the presence of equal amount water in both the environment i. e. cell and outside environment so due to equal amount of water, contractile vacuole become less active.

If the carrying capacity of the pond is 1,500 for this species, what is the expected population size after one year

Answers

Answer:

450

Explanation:

A fish population of 250 in a pond has a maximum annual rate of increase of 0.8. If the carrying capacity of the pond is 1,500 for this species, what is the expected population size after one year?

The annual rate of increase in the population is 0.8 and the population is currently 250 in the pond, hence, the expected population size after one year can be calculated as thus:

Expected increase in the population = 0.8 x 250

     = 200

Expected population size after one year = 250 + 200

       = 450

Since a population of 450 has not exceeded the carrying capacity of the pond, the expected population size after one year is, therefore, 450.

The expected population size after one year is 450

Data obtained from the question

•Current population = 250

•Annual rate of increase = 0.8

•Expected population size =?

Determination of the expected increase

We'll begin by calculating the expected increase in the pond. This can be obtained as follow:

•Current population = 250

•Rate of increase = 0.8

•Expected increase =?

Expected increase = Current population × rate

Expected increase = 250 × 0.8

Expected increase = 200

Determination of the Expected population size

•Current population = 250

•Expected increase = 200

•Expected population size =?

Expected population size = Current population + Expected increase

Expected population size = 250 + 200

Expected population size = 450

Complete question:

A fish population of 250 in a pond has a maximum annual rate of increase of 0.8. If the carrying capacity of the pond is 1,500 for this species, what is the expected population size after one year?

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Which human activity would help reduce the amount of carbon dioxide in the atmosphere

Answers

Answer:

Burning coal  

Explanation:

The emissions of carbon dioxide would reduce because then they will consume less gasoline. Instead of coal burning, this would reduce the overall concentrations of greenhouse gas emissions and generate energy from wind.

The world has been through 5 mass extinction events. We lost over 50% of the species on the planet
each time they happened. How do you think the Earth would be different if we did not have any
extinction events?

Answers

Answer: yes because 50% more palnts and animals would be alive.

Explanation: no cap

During _____ women experience rapid contractions around the vagina that may or may not produce a vaginal secretion or ejaculate.

Answers

Balling usual like Kobe not worried about a hater that don’t know me

Assuming you started with a saturated hemoglobin molecule, how many molecules of oxygen would need to be released in order for the hemoglobin to be 75% saturated

Answers

Answer:

only one oxygen molecule  

Explanation:

Hemoglobin (Hb) is an iron-containing oxygen-transport protein localized in vertebrate red blood cells (i.e., erythrocytes). Moreover, the heme group is a component of the Hb protein which is capable of binding or releasing molecular oxygen. Hb consists of four globular protein subunits, and each subunit contains a heme group. This group (heme) binds to an oxygen molecule in a manner that each Hb protein can bind to four oxygen molecules in order to transport them throughout the bloodstream.

Help please !

A strand of messenger RNA (MRNA) has the nucleotide
sequence GAA. This corresponds to an amino acid called leucine.

Which three nucleotides does the transfer RNA (TRNA) carrying leucine have?

Select one:

1. CGG
2.CUU
3.AGG
4.ACC

Answers

Answer:

2. CUU

Explanation:

i did some research

CUU are the nucleotides which transfer RNA carrying leucine. So, the correct option is (B).

What is RNA?

RNA stands for Ribonucleic acids which is present in all living cells and have structure similarities to DNA.

It is a single stranded structure. It has a backbone made up of alternative phosphate group and the sugar ribose. Sugar is attached to one of the four bases. They are adenine (A), uracil (U), cytosine (C) or guanine (G).

There are three types of RNA which exist in cells messenger. They are  messenger RNA (mRNA), ribosomal RNA (rRNA) and transfer RNA (tRNA).

1. Messenger RNA (mRNA) is translated into a polypeptide.

2. Transfer RNA (tRNA) will bind an amino acid to one end and has an anticodon on the other.

3. Ribosomal RNA (rRNA) helps facilitate the bonding of amino acids coded for by the mRNA.

Some of the RNAs are involved in gene expression regulation. As per the Central dogma of Molecular Biology, main role of RNA is to convert the information which is stored in DNA into proteins through the process called transcription.

Thus, CUU are the nucleotides which transfer RNA carrying leucine. So, the correct option  is (B).

Learn more about RNA, here:

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#SPJ2

What type of mutation causes a change in what amino acid the DNA strand
codes for?
Silent
Non Silent

Answers

Answer:

Non Silent

Explanation:

Mutation, is generally, any change or alteration to the genetic sequence of a DNA. However, mutation can be of different types depending on how it occurs. According to this question, a mutation is said to be SILENT if it involves the substitution of a nucleotide with another nucleotide that does not change the protein molecule encoded by the gene. In other words, the mutation happens in such a way that both the original sequence of gene and the mutated one codes for the same amino acid sequence (protein).

On the other hand, a mutation is NON SILENT i.e missense or nonsense mutations, if the mutation causes a change in what amino acid the DNA strand codes for. For example, in missense mutation, a different amino acid is produced while in nonsense mutation, a STOP codon is produced.

Which scenario is an example of a scientific way of thinking?

A. A scientist writes a play that illustrates the challenges monarch
butterflies face on their long, yearly migration.

B. A scientist collects monarch butterfly specimens from each part
of their life cycle and creates a display.

C. A scientist observes the different parts of the life cycle of
monarch butterflies and collects detailed descriptions.

D. A scientist talks to various organizations about the importance of
preserving habitats vital to the survival of monarch butterflies.

Answers

Answer:

C To make observations

Explanation:

you need to form questions,making hypothesis and analysing the data

Answer:

C. A scientist observes the different parts of the life cycle of

monarch butterflies and collects detailed descriptions.

Explanation:

Apex

What are the four body parts that a flatworm has?

Answers

4/+3 equals 46% From his green violet orange

WILL GIVE BRAINLIST FOR CORRECT ANSWERS

Answers

Answer:

wave b

Explanation:

Which explanation describes why males are more likely to exhibit sex-linked disorders than females? Males have two X chromosomes that amplify all sex-linked disorders. Males have one X chromosome on which most sex-linked disorders are located. Males have only one functional sex chromosome on which all gender traits are located. Males have multiple sex chromosomes that mutate causing sex-linked disorders to become visible.

Answers

Answer:

males have one X chromosome

Explanation:

The explanation that describes why M are more likely to have linked disorders than W is that M have an X chromosome on which most linked disorders are located.

Inheritance

Linked inheritance refers to genes located on chromosomes that are involved in trait determination.

In humans, the male  chromosome Y has few genes. On the other hand, the female chromosome X has a large number of genes involved in the determination of various characteristics.

XY chromosomes have small homologous regions at their ends. Thus, there is practically no recombination between their genes.

When the altered gene is on the X chromosome. This type of inheritance has a recessive pattern.

It is the maternal inheritance. In this case, sons inherit X chromosome genes only from their mother. Meanwhile, F daughters inherit one from the father and one from the mother.

The manifestations will be present because they have only one X chromosome, that is, they do not have any normal gene for that characteristic.

With this information, we can conclude that the manifestations will be present in men, as they have only one X chromosome.

Learn more about Chromosome in https://brainly.com/question/296477

Can glucose be directly used for energy

Answers

Insulin helps glucose enter the body's cells to be used for energy. If all the glucose is not needed for energy, some of it is stored in fat cells and in the liver as glycogen.

Why is meiosis important for organisms?
It creates gametes and allows for genetic variation among organisms.
It produces genetically identical cells.
0 It provides a means of asexual reproduction.
O It allows for cell and tissue repair

Answers

The correct answer is A. It creates gametes and allows for genetic variation among organisms.

Meiosis is the process of cell division in which a single cell divides into four daughter cells. The genetic constitution of the daughter cells reduces to the half as compared with the parent cells. While crossing over, an exchanging of genetic material is passed between chromosomes and that allow variations to happen.

Describe an experiment you would perform to test a proposed chloroplast-targeting signal sequence. Be specific about the type of cell and the proteins you would use. Describe the results you would expect if the sequence is indeed a chloroplast-targeting signal.

Answers

Answer:

I would fuse the gene encoding the protein carrying the putative chloroplast-targeting signal sequence with the gene encoding Green Fluorescence protein. The GFP-tagged target protein enable to study the expression of the putative chloroplast localization signal sequence and its final cellular localization

Explanation:

The Green Fluorescence protein (GFP) is a protein widely used in molecular biology to investigate the expression of specific genes and then track the movement of proteins in living cells. This protein also can be used as a cell marker and to identify protein-protein interactions. When GFP is excited to a given wavelength (excitation peak 395 nm), it emits green light (emission peak 509 nm), thereby the expression/localization of the GFP-target fusion constructs can be evidenced by using a fluorescence microscope.

Water vapor GAINS energy when it CONDENSES into a liquid.

A. True
B. False

Answers

Answer:

Explanation:

B. False  it loses energy in the form of heat. Therefore, this process is exothermic.

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