In most cases, mutations in the core of a protein that replace a smaller nonpolar side chain in the wild-type (e.g., Ala, Val) with a larger nonpolar side chain (e.g., Leu, Ile, Phe, Trp) in the mutant, result in significant destabilization and misfolding of the mutant. What feature of the protein core explains this observation? Why would such a mutation prevent a protein from folding properly? Match the items in the left column to the appropriate blanks in the sentences on the right.
Answers
Explanation:
we are required to fill in the blank spaces in the attachment.
protein side chains are non polar. so the first answer is non polar. These side chains are hydrophobic in nature. so the second blank is hydrophobic. Non polar substances are known to have large number of van der waal forces. the third answer is large and the fourth is vanderwaals contact. the protein core destabilizes only when there is a weakening of vanderwaals contact which brings about mutation.
dear user your answer should look like this:
Interactions of non polar side chains in protein sequence lead to the formation of a tightly packed hydrophobic core. This core is stabilized by a large number of vanderwaals contact. When a mutation occurs, it destabilizes the protein core and weakens vanderwaals contact leading to misfolding
Related Questions
What processes are necessary in order to turn sand into rock?
Answers
Answer: The three main rock types are igneous, metamorphic and sedimentary. The three processes that change one rock to another are crystallization, metamorphism, and erosion and sedimentation. Any rock can transform into any other rock by passing through one or more of these processes. This creates the rock cycle.
Explanation: thats the rock cycle.. yw
Answer:
Compaction and cementation
Explanation: I took the test and got it all right so i hoped this helped :)
Question 5
1 pts
Bacteria play a vital role in all of the following processes of the nitrogen cycle expet for
O fixation
O nitrification
O denitrification
O assimilation
Answers
Answer:
except for assimilation
please help me fast!!
Answers
Answer:
they are not living because when they fell from the tree they stopped getting water. so it depends on how long ago they fell.
Answer:
I would agree that the leaves that have fallen are dead. I agree because it is a proven fact that, when a leaf is not conected to a tree it will die because it is not geting protens or food from the tree anymore.
Explanation:
MARK AS BRAINLISTWhat influences the amplitude of waves
Answers
The amount of energy carried by a wave is related to the amplitude of the wave. ... Putting a lot of energy into a transverse pulse will not effect the wavelength, the frequency or the speed of the pulse. The energy imparted to a pulse will only affect the amplitude of that pulse.
How would an asthma attack most like affect oxygen delivery in the body
Answers
Answer:
Oxygen delivery would be decreased due to a decrease in the air intake.
Explanation:
what is the best example of equilibrium would be isotonic, hypertonic, hypotonic, facilitated diffusion
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Answer:
isotonic
Explanation:
In order to prevent the cells from either swelling or shrinking, the body fluids should be isotonic, meaning that they are at equilibrium.
A sudden increase in the amount
of available nutrients can create
problems for an aquatic
ecosystem. How?
A. Large numbers of producers can confuse
herbivores.
B. Increased nutrients can cause producers to
compete aggressively with one another.
C. There is not enough oxygen in the
atmosphere to support excessive numbers of
aquatic plants.
Answers
Answer:
C
Explanation:
There would be a high amount of nitrates and phosphates, which reduces the amoubt of oxygeb in the tank, that will lead to the difficulty of supportibg the excessive amount of aquatic plants.
Answer:
C. There is not enough oxygen in the
atmosphere to support excessive numbers of
aquatic plants.
Explanation:
n excess amounts, both nutrients can cause an increase in aquatic plant growth and algae blooms, called eutrophication. These algae blooms live at the water surface, in order to easily access oxygen and sunlight. As a result, eutrophication prevents lower water levels from access to sunlight and oxygen in the air.
Solve this question?
Answers
Answer:
Tissue level
Explanation:
PLEASE help
If anyone know which it is please tell
thank you
Answers
Answer:
Explanation:
Because there not like humans they don't move very much they still need water and sunlight though make sure they get sunlight daily and water weekly - for number9 !! hope its right
Answer:
6) Plants create photosynthesis to get energy, animals eat waste and other organisms.
7) Yes, the body does get all the energy from the sun. When we eat animals that eat plants, the energy from CR goes to the consumers.
8) No, CR is the result of photosynthesis, if no CR were around, photosynthesis could not begin.
9) Plants needs energy to help move things in and out of the cell. Plants also need energy to grow and reproduce.
(Q005) Humans are unusual because our cultural practices can actually change our environmental circumstances. We can change the environment in which natural selection acts on our traits. Describe how this process has played out in the evolution of adult lactose tolerance. Can you hypothesize any similar situations where our future evolution may be influenced by cultural practices we have today
Answers
Answer:
Lactose tolerance conferred an evolutionary advantage, thereby this beneficial mutation increased its frequency in the population
Explanation:
Originally, adults were unable to digest lactose. But approximately 8,000-10,000 years ago something remarkable happened: a mutation near the gene that produces the lactase enzyme appeared in a raising cattle population from Europe-Middle East, making adults able to digest lactose. Nowadays, many adults from different societies are tolerant to digest lactose because this mutation increased its frequency and extended to different populations. It is a classical example of how a beneficial mutation may eventually become the most common gene variant by increasing its frequency in the population, and, subsequently extending to other populations. It is possible to hypothesize that new mutations associated with human activities may appear in current human societies, thereby conferring an evolutionary advantage in the same way that lactose tolerance in cattle-raising people. For example, nowadays, mutations in human behavior-associated genes might confer beneficial social skills (thereby increasing the frequencies across time or across populations).
Which of the following identify as fungi or parts of fungi
Answers
Answer:i have no idea
Explanation:
how is tertiary structure maintained?
1) via hydrogen bonding between R groups
2) via ionic bonding between R groups
3) via covalent bonding between R groups
4) all of the above
Answers
Answer:
All three of these bonds hold the R groups of the amino acids together.
Explanation:
The structures are stabilized by multiple interactions, specifically side chain functional groups which involve hydrogen bonds, salt bridges, covalent disulfide bonds, and hydrophobic interactions.
- Hydrogen bonding
- Salt bridges (ionic bonding)
- Covalent disulfide bonds (Covalent Bonding)
- All in R groups
Which best describes the nucleus of an atom?
a. It is thee negatively charged part of the atom
b. It contains no mass.
c. it is made of neutrons and electrons.
d. It is the most massive part of the atom
Answers
Answer:
The answer is D.
I used the process of elimination to find your answer if you want to understand further look in my explanation. I hope I can help! Have a great day!
Explanation:
So the negatively charged part of a atom is the electron cloud so A is wrong because it would be in the wrong spot. Plus the nucleus is positively charged because it contaims only protons ans neutrons. Neutrons are neutral and protons are positive so the protons over power the nuetrons. Therefore the nucleus is not made of neutrons and electrons so C is wrong. And B is also wromg because the nucleus does indeed have mass. So the correct answer is D, it is the most massibe part of a atom.
What are the products of cellular respiration ?
Answers
Which statement best explains why less energy is available to organisms as a food chain gets longer?
Answers
B.Organisms use some of the energy for life processes
Energy is able to stored be but not be changed
Answers
Answer:
false
Explanation:
Energy is always being transferred and changes form.
what is culture
a-the racial makeup and physical attributes of a group of people b-the music and art of people c-the behaviors and believes of a group of people d-a state made up of distinct cultural groups
Answers
I believe the answer is c
what chemical reaction takes place between an egg shell and vinegar ?
Answers
Answer:
The reaction of the eggshell in vinegar is an acid-base reaction. When you submerge an egg in vinegar, the shell dissolves, leaving the inner semi-permeable membrane intact. Vinegar (acid) breaks apart the solid calcium carbonate crystals (base) in the eggshell into their calcium and carbonate parts.
Explanation:
The reaction of the eggshell in vinegar is an acid-base reaction. When you submerge an egg in vinegar, the shell dissolves, leaving the inner semi-permeable membrane intact.
Vinegar (acid) breaks apart the solid calcium carbonate crystals (base) in the eggshell into their calcium and carbonate parts.
What is an example of an acid-base reaction?A salt is a product of an acid-base reaction and is made up of the cation from the base and the anion from the acid. Hydrochloric acid reacts with sodium hydroxide to form sodium chloride (a salt) and water.
Thus, it is type of acid base reaction.
To learn more about acid-base reaction click here:
https://brainly.com/question/15220646
In a solar eclipse the sunlight is blocked by?
Answers
Answer:
The sun should be blocked by the moon.
Answer:
the moon
Explanation:
Which of the following are types of Archaea?
Answers
Answer:
Your question was a bit vague... but Crenarchaeota, Euryarchaeota, Korarchaeota, Thaumarchaeota and Nanoarchaeota are the four types of Archaea.
Hope this helps!
Coca-Cola owns a massive fleet of delivery trucks that have contributed 3.7 million metric tons of greenhouse gases to the atmosphere so far. Coca-Cola
decided to change by investing in new trucks that use alternative energy to do their deliveries. Their goal is to reduce their carbon footprint by 25% by the year
2020. What's this an example of?
A. Corporate responsibility
B. Market-based approach
C. Government incentive
D. Tragedy of the Commons
Answers
Which is an example of the bottleneck effect?
A. Green beetles move to a new location and build a new colony there.
B. Green beetles survive as birds don’t see them , whereas brown beetles get detected.
C. Insecticide spraying eliminates all but a few of the beetles on a island .
Answers
Which of the following is an aspect of consciousness that is a key to self-control?
a. Countertransference
b. Selective attention
C. Centration
d. Cognitive dissonance
Answers
Answer:
a. countertransference
The
of a bacterium controls transport of compounds into and out of the cell.
Select one:
O plasma membrane
O cell wall
O Golgi apparatus
O electron transport chain
Answers
Describe how dawin's theroy of evolution by natural selection can explain the spread of antibiotic-resistant microorganisms which caused the return of Latasha's strep throat
Answers
how do trees prevent flooding
Answers
Answer: the trees prevent flooding by the water so when water is higher it prevents flood
Answer:
by
Explanation:
your basement flooded once, it can happen again. Fortunately, there’s a lot you can do to prevent a flooded basement. That’s where we come in. As a basement waterproofing company, Ohio Basement Systems offers basement flood prevention and waterproofing solutions that will ensure that your basement stays dry.
Call us today or fill out the form for your no-obligation, free inspection and estimate. We’ll provide peace of mind and customize a solution to help you solve your basement flooding problems. We offer free estimates on all our services in Cleveland, Akron, Strongsville and the nearby areas.
3. Which of the following is an example of volume?
O A. 25 mL of rubbing alcohol in a graduated cylinder
B. 50 grams in a pencil
C. 3 meter piece of wood
O D. 10 kilogram boulder
Answers
25 ml of rubbing alcohol in a graduated cylinder
volumes si unit is cubic metre.
other units: Litre, fluid ounce, gallon, quart, pint, tsp, fluid dram, in3, yd3, barrel
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A. 25 mL of rubbing alcohol in a graduated cylinder.Others represent mass of that substance .
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HOPE IT HELPS
PLEASE MARK ME BRAINLIEST ☺️
How do bacteria help plants grow?
They break down carbon dioxide into carbon and oxygen.
They protect plants from pollution from acid rain and hydrocarbons.
They change ammonia into nitrogen gas for plants to use to make proteins.
They change nitrogen into nitrates plants use to make proteins.
Answers
Answer:
They change nitrogen gas into nitrates for plants to make proteins.
Explanation:
Nitrifying bacteria and Nitrogen-fixing bacteria work together to convert nitrogen gas into nitrates which plants use to make DNA, RNA, and amino acids (which are used to make other proteins).
Bacteria help to plant growth by changing nitrogen (N element) into nitrates plants use to make proteins.
How do bacteria help plant growth?Bacteria help to plant growth by helping nitrogen assimilation during different metabolic processes.
This nitrogen is fundamental to synthesizing proteins, which are mainly composed of this element.In conclusion, bacteria help to plant growth by changing nitrogen (N element) into nitrates plants use to make proteins.
Learn more on the Nitrogen cycle here:
https://brainly.com/question/610563
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15. Which of the following shows the correct sequence of what happens to the water molecules in an ice
cube when it is removed from the freezer?
(1 point)
1. The molecules gain enough energy to break free from each other.
2. The ice begins to melt.
3. The molecules vibrate in a fixed position.
4. The temperature of the of molecules increases.
5. Thermal energy is absorbed from the surroundings.
6. The molecules vibrate faster.
0 3,1,4,6,5,2
O 5,1,4,6,3,2
O 3,5,6,1,2,4
O 5,3,1,4,6,2
Answers
Answer:
the second one because the just start to melt
Which of the following is most appropriate unit to measure the distance Phoenix to Rocky Point ( Puerto Penasco), Mexico?
Answers
Answer:
Probaly miles or kilometers
Explanation: