Warfarin acts by inhibiting the activity of the VKORC1 protein, which helps to produce functional clotting factors. There is a variant in the VKORC1 gene that lowers the dose of warfarin required for treatment, and individuals with this variant have increased risk of bleeding when they are treated with warfarin. This variant is found 1639 base pairs upstream of the translational start site. This variant likely:______.
a. decreases the activity of the VKORC1 protein.b. increases the activity of the VKORC1 protein.c. decreases expression of the VKORC1 gene.d. increases expression of the VKORC1 gene.
Answer:
The correct answer - c. decreases expression of the VKORC1 gene.
Explanation:
Mutation of Guanine nucleotide into Adenosine is the reason for this particular type of mutation. This mutation expresses the less expression of the VKORC1 protein.
The mutation results in a decrease in the affinity of the binding site of the transcription factor which causes less expression. Since the VKORC1 protein is less in the body so Warfarin doses are decreased
Thus, the correct answer is - decreases expression of the VKORC1 gene.
Pls help thank you
A group of geologists is about to start excavating a new area for fossils. The area they are working in is the side of a cliff. Describe two pieces of information they will most likely be able to discover about the fossils they will find.
Answer:
Forms of fossils and there arrangement with layer of rock.
Explanation:
The seashore is a significant place for the depositional work of waves and it's also one of the significant places for the erosion and weathering of rocks. The presence of sedimentary rocks along the cliffs are essential for the discovery of fossils of plants and animals. Fossils of shells and other creatures that were of marine origin are mostly discovered near excavation sites. Fossil helps to prove the age of rocks and strata.What is the correct volume of air to deliver during BVM ventilations?
The only Purple Animal is the South African____?
Answer:
Okapi
Mark Brainliest
okapi...
hopr helps uh
..yhnk my ansr
In pulsus paradoxus, even if the pulse cannot be palpated, it can still be heard by using a BP cuff and stethoscope.
a. True
b. False
Answer:
False.
Explanation:
Pulse can't be heard by using a BP cuff and stethoscope because these devices are used to measure the heartbeat and blood pressure of the body. Digital monitors display both blood pressure and heart rate, but you can determine the pulse by checking your pulse by using hand while on the other hand, heartbeats can easily be heard using a good stethoscope so we can say that pulse can't be heard through BP cuff and stethoscope.
which fundamental units are involved in force do step Wise
Force = ma
We know, the unit that the S.I. unit of mass is Kg.
We also know that a = (v - u)/t.
We know that v = d/t and u = d/t and the S.I. unit of t(time) is s.
We know that the S.I. unit of d(displacement) is m.
So, the S.I. unit of v is m/s and the S.I. unit of u is m/s and the S.I. unit of t is s.
So, the S.I. unit of a is m/s×s or m/s²
So, the unit of force is
(unit of m) × (unit of a)
= kg × (m/s²)
= kg.m/s²
=
[tex]kg \: m \: {s}^{ - 2} [/tex]
Or more simply,
F = ma
=> F = m{(v-u)/t}
Putting units,
Newton = kg[{(m/s) - (m/s)}/s]
=> Newton = kg{(m/s)/s}
=> Newton = kg(m/s²)
=> Newton = kg.m/s²
=> Newton = kg.m.(s^-2)
Sickle cell anemia in the United States disproportionately affects African Americans; 1 in 700 African Americans are affected by sickle cell anemia, while only 1 in 160,000 Americans of European descent are affected. The absolute risk of a newborn African American child having sickle cell anemia is ____________%, and the relative risk compared to a newborn European American child is ____________-fold
Answer:
0.0014; 0.0044
Explanation:
The absolute risk (AR) of a disease refers to the risk of developing the disease over a given time period. In this case, the absolute risk of the newborn African American child having sickle cell anemia is equal to 1 individual with the disease over 700 individuals >> AR = 1 / 700 = 0.0014. Moreover, the Relative Risk (RR) is calculated by comparing the likelihood of the absolute risk occurring between two distinct groups. In this case, the relative risk for the newborn African American having sickle cell anemia compared to a newborn European American child can be calculated by dividing the absolute risk of the newborn European American child with the measured absolute risk of the newborn African American child >> RR = 0.0000625 / 0.0014 = 0.0044.
How old is the sun?
Our little teenage Sun is nearly 4.6 billion years old.
A scientist is tracking an object orbiting the Sun that is found between Mars and Jupiter. Which additional feature can
be used to determine the object is an asteroid?
O produces a coma
O has an irregular shape
O has a tail of ice and dust
O produces a streak of light
Answer:
The correct answer is actually B. Has an irregular shape.
Which best explains why sawdust burns more quickly than a block of wood of equal mass under the same conditions?
The molecules move more quickly in the sawdust than in the block of wood.
The pressure of oxygen is greater on the sawdust.
More molecules in the sawdust can collide with oxygen molecules.
Oxygen is more concentrated near the sawdust than the block of wood.
Which best explains why, under the same circumstances, sawdust burns more fast than a wood block of equivalent mass The molecules in the sawdust move more swiftly than those in the
A thermal burn is what?
An injury to the skin or other organic tissue known as a burn is one that is primarily brought on by heat, radiation, radioactivity, electricity, friction, or contact with chemicals. When hot liquids, heated solids, or flames come in touch with the skin and other tissues, part or all of the skin's cells are destroyed (flame burns)
What various sorts of Burns are there?
This tiny burn merely penetrates the skin's surface layer (epidermis). It might hurt and make you red. second-degree burn Both the epithelium and the next layer of skin are affected by this kind of burn (dermis). It could result in skin that is swollen, red, white, or patchy. The pain may become intense and blisters may form. Scarring may result from second-degree burns that are deep.
To know more about burns visit:
https://brainly.com/question/14152400
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Answer:
C.More molecules in the sawdust can collide with oxygen molecules.
Explanation:
real
In a test cross, a pure-breeding plant is crossed with a plant suspected to be heterozygous (Aa). What is the genotype of the pure-breeding plant?
Answer:
aa
Explanation:
In genetics, a test cross is a cross performed to determine the unknown genotype of a phenotypically dominant organism. The test cross is done by crossing the unknown genotype with a homzygous recessive organism. The result of this cross tell us whether the unknown genotype is heterozygous or homzygous dominant.
According to this question, a test cross was conducted involving a pure breeding plant with a plant suspected to be heterozygous (Aa). Based on the explanation of a test cross above, the genotype of the pure-breeding plant will be "aa". Note; it must be recessive.
do both plant cells and prokaryotic cells have 70S ribosomes
What would be the most likely result if humans stopped burning fossil fuels?
Answer:
It allows an ozone layers not to be greatly in big holerelease fresh airAnswer:
If human stop burning fossil fuels then the condition and pollution will desperate. There would be more carbon dioxide and less oxygen.
hope it helps you!!!First, you introduce to the parents the importance of karyotype test, by describing its ability to detect two broad categories of abnormalities in chromosomes, (1)______________________ and (2)_______________________. You provide a few examples of genetic disorders that can be caused by chromosomal abnormalities, such as (3)_________________________ and (4)_____________________. Some parents would like to know what is the main cause of these genetic disorders. Without going into too much detail, you explain to them that chromosomal abnormalities are usually caused by (5) ____________________ in meiosis I and meiosis II, when the homologous chromosomes or sister chromatids fail to separate during meiotic cell division.
Answer:
Abnormalities in Chromosomes
1. Numerical
2. Structural
3. Down Syndrome
4. Turner Syndrome
5. Disorder or Error
Explanation:
Numerical chromosome abnormalities occur due to extra or missing chromosomes. Structural chromosome abnormalities occur due to the irregular formation or rearrangement of the chromosomal DNA, normally called translocation. Down syndrome occurs with extra chromosomes, more than 46. Turnover syndrome results from partial or missing X chromosomes, less than 46.
A penicillin reaction is a life-threatening event. In those who are allergic to penicillin, the drug acts as a __________ that binds to blood proteins, causing a strong immune response.
Answer:
A penicillin reaction is a life-threatening event. In those who are allergic to penicillin, the drug acts as a hapten that binds to blood proteins, causing a strong immune response.
Explanation:
Low molecular weight chemicals can bind to antibodies, but cannot activate B lymphocytes by themselves (they are not immunogenic). To generate specific antibodies to these small chemicals, immunologists typically bind them to macromolecules prior to immunization. In these cases, the chemical is called a hapten. Penicillin G is a typical hapten that tends to covalently bind to lysine residues both in solution and in protein-bound cells. Penicillin is a drug that behaves as a hapten, since the beta-lactam ring under physiological conditions opens and reacts with the lysine residues of proteins, forming a complex that is the main antigenic determinant of penicillin and other beta-lactams and is capable of to stimulate responses mediated by antibodies or by T cells.
What kind of interaction does this image show, which acts as limiting factor on the fish?
A. mutualism
B. Parasitism
C. Commensalism
D. Predation
E. Exploitation competition
Answer:
Predation
Explanation:
The cat is the predator and the fish is its prey.
Answer:
predation
Explanation:
because
What are three techniques that can be used to show that the electron transport chain is found on the matrix side of the inner mitochondrial membrane. Select all that apply.
Answer:
Explanation:
Step 1: Generating a Proton Motive Force
The hydrogen carriers (NADH and FADH2) are oxidised and release high energy electrons and protons
The electrons are transferred to the electron transport chain, which consists of several transmembrane carrier proteins
As electrons pass through the chain, they lose energy – which is used by the chain to pump protons (H+ ions) from the matrix
The accumulation of H+ ions within the intermembrane space creates an electrochemical gradient (or a proton motive force)
Step Two: ATP Synthesis via Chemiosmosis
The proton motive force will cause H+ ions to move down their electrochemical gradient and diffuse back into matrix
This diffusion of protons is called chemiosmosis and is facilitated by the transmembrane enzyme ATP synthase
As the H+ ions move through ATP synthase they trigger the molecular rotation of the enzyme, synthesising ATP
Step Three: Reduction of Oxygen
In order for the electron transport chain to continue functioning, the de-energised electrons must be removed
Oxygen acts as the final electron acceptor, removing the de-energised electrons to prevent the chain from becoming blocked
Oxygen also binds with free protons in the matrix to form water – removing matrix protons maintains the hydrogen gradient
In the absence of oxygen, hydrogen carriers cannot transfer energised electrons to the chain and ATP production is halted
what are the difference between DNA and RNA
Answer:
There are two differences that distinguish DNA from RNA: (a) RNA contains the sugar ribose, while DNA contains the slightly different sugar deoxyribose (a type of ribose that lacks one oxygen atom), and (b) RNA has the nucleobase uracil while DNA contains thymine.
Activity 3: Direction: Study the picture. Write the phases of the moon 1 new moon O first quarter O MOON PHASES last quarter waning crescent woving crescent Waning gibbous working globos
Answer:
1.full moon
2.waxing gibbous
3.first quarter
4.waning gibbous
5.new moon
6.wabing cresent
7.last quarter
8.waxing cresent
What is a group of microscopic unicellular organisms
Modelizar un ecosistema colocando los niveles tróficos y las relaciones en la red alimentaria
Answer:
Ejemplo ecosistema y su cadena trófica:
- Ecosistema: llanura (campo de maíz)
- Productor primario: plantas de maíz
- Consumidor primario: Ratones
- Consumidor secundario: Aves rapaces
- Microorganismo descomponedor: bacterias
Explanation:
En una cadena trófica o cadena alimentaria de un ecosistema, cada nivel obtiene la energía necesaria para sustentar la vida a partir del nivel inmediatamente anterior, mientras que los productores primarios son aquellos organismos que hacen ingresar la energía al ecosistema. Por otra parte, los descomponedores son organismos que se alimentan de los restos de animales y plantas, mediante su descomposición, obteniendo de ellos energía y materia hasta transformarlos en materia inorgánica. En el ejemplo arriba citado, las plantas de maíz representan los productores primarios los cuales producen energía y materia orgánica requerida para sustentar el ecosistema mediante el proceso de fotosíntesis. En segundo lugar, los ratones, como así también otros organismos herbívoros, representan los consumidores primarios los cuales conforman el segundo nivel trófico de la cadena alimentaria. En tercer lugar, los animales carnívoros que se alimentan de consumidores primarios (como por ejemplo, aves rapaces) representan el tercer nivel trófico, y así sucesivamente niveles superiores en el caso que existan depredadores mayores en el ecosistema. Finalmente, bacterias y otros organismos (por ejemplo, hongos, lombrices, algunos insectos, etc) representan los descomponedores los cuales se alimentan de restos orgánicos en descomposición, transformándolos de este modo en compuestos inorgánicos que ingresan nuevamente al ecosistema.
Use the coordinates of the labeled point to find the point-slope equation of
the line
-5
5
-5
(3.-5)
O A. y+ 5 = -3(x - 3)
B. y- 5 = -3(x+3)
C. y + 5 = 3(x+3)
O D. Y-3 - (x+5)
Answer:
A. y + 5 = -3(x - 3)
Explanation:
Given the following data;
Points on the graph (x1, y1) = (3, -5)
Points on the graph (x2, y2) = (0, 4)
First of all, we would determine the slope of the equation of line;
Mathematically, the slope of a line is given by the formula;
[tex] Slope, \ m = \frac {Change \; in \; y-axis}{Change \; in \; x-axis} [/tex]
[tex] Slope, \ m = \frac {y_{2} - y_{1}}{x_{2} - x_{1}} [/tex]
Substituting into the formula, we have;
[tex] Slope, \ m = \frac {4 - (-5)}{0 - 3} [/tex]
[tex] Slope, \ m = \frac {4 + 5}{0 - 3} [/tex]
[tex] Slope, \ m = \frac {9}{-3} [/tex]
Slope, m = -3
Next, to find the point-slope equation of the line, we would use the following formula;
y - y1 = m(x - x1)
y - (-5) = -3(x - 3)
y + 5 = -3x + 9
y = -3x + 9 - 5
y = -3x + 4 = mx + c
Which tool is a meteorologist most likely to depend on to collect information from the
upper atmosphere?
Answer:
Anemometer is the most likely meteorologist to collect information from the high atmosphere.
Explanation:
A device to measure wind velocity and direction is an anemometer. It's also a common meteorological tool. The name comes from the Greek phrase anemos that means wind and is used to designate any meteorological wind speed instrument.
Anemometer uses
The anemometer is used for the following purposes other than to measure the wind speed:
For wind pressure measurementIn order to measure wind flowMeasuring the wind directionIt is used to assess weather conditions before testing its gadgets by drone users or RC aircraft usersUsed also by snipers and pilots of long-rangeSkydivers are used to assessing wind speed before they spring into the abyss.Used to measure airspeed in aerodynamicsAnswer:
weather balloon
Explanation:
5. Shawn has a hypothesis that fungicides harm bee development. Using what you now know, describe an experiment to test Shawn’s hypothesis. Be sure your response includes what data should be collected and how you would collect it.
Answer:
Yes.
Explanation:
Yes, the fungicides harm bee development by causing changes in behavior, immune health, and reproduction etc. For verifying this hypothesis, we have to take two environments, in one environment fungicides are applied to the plants while on the other environment, there is no fungicide applied to the plants. Th result shows that the bees are affected and act abnormal where fungicides are applied as compared to those bees which are normal in behaviour and other features.
What is the complementary DNA strand for this DNA strand : GTTACGAACT
Answer:
CAATGCTTGA
Explanation:
Look at the scientific names for the two organisms below:
Felis domesticus
Felis bengalensis
What can you tell about these two organisms from their scientific names?
A.
You cannot tell anything about an organism from its scientific name alone.
B.
The organisms are different subgroups of the same species.
C.
The organisms are different species but belong to the same genus.
D.
The organisms belong to the same kingdom but different phyla.
Answer:
B. The organisms are different subgroups of the same species.
QUESTION:-
Felis domesticus (Domestic CAT)
Felis bengalensis (Leopard Cat)
What can you tell about these two organisms from their scientific names?
A.
You cannot tell anything about an organism from its scientific name alone.
B.
The organisms are different subgroups of the same species.
C.
The organisms are different species but belong to the same genus.
D.
The organisms belong to the same kingdom but different phyla.
ANSWER:-
FIRST PART IS THE GENERIC PART ( genus name )
SECOND PART IS THE SPECIFIC NAME ( specific epithet )
ATQ:-
AS THE GENERIC OR GENUS NAME SAME SO THEY BELONG TO SAME GENUS
BUT DUE TO DIFFERENT SPECIFIC NAME OR SPECIFIC EPITHET WHICH SHOWS THAT THEY BELONG TO DIFFERENT SPECIES .
SO URE ANSWER IS PART C->
C. The organisms are different species but belong to the same genus.Answer this question properly
there are two types of white blood cell phagocyte and lymphocytes how lymphocytes work?
Answer:
Through receptor molecules on their surfaces, lymphocytes are able to bind antigens
Explanation:
Lymphocytes are the cells responsible for the body's ability to distinguish and react
Answer:
1. lymphocytes
2. phagocytes
3. monocytes
Explanation:
100%
Question 4 Multiple Choice Worth 2 points)
In the diagram below, what is the property of the wave indicated by the letter A?
- amplitude
- crest
-frequency
-trough
Answer:
- trough.
Explanation:
The Trough is the lowest wave section, the minimum wave part. It's the other way around from crest.A wave or alternating signal minimal point.A long, narrow depression, waves or ridges between them.A low point in a corporate cycle or on a graph.An extended area of relatively low pressure, often in conjunction with the front.What is an office what is an office
Answer:
Explanation:
An office can be referred to a building or rooms or a room which is arranged and set up with furnitures and things needed for commercial use or professional work to achieve a goal.
An office is also refered to position of authority occupied by someone to perform some tasks.
Answer:
here's your answer
Explanation:
The office helps in controlling the activities of different people and department of an organisation. Through controlling it ensures that the various activities of business are performed with much accuracy. Memory Center: Office protects important information of past in a safe manner.