Cystic fibrosis is most common in individuals of Northern European descent, affecting 1 in 3200 newborns. Assuming that these alleles are at Hardy-Weinberg equilibrium, what is the frequency of the disease-causing CFTR alleles in this population

Answers

Answer 1

Answer:

0.0177

Explanation:

Cystic fibrosis is an autosomal recessive disease, thereby an individual must have both copies of the CFTR mutant alleles to have this disease. The Hardy-Weinberg equilibrium states that p² + 2pq + q² = 1, where p² represents the frequency of the homo-zygous dominant genotype (normal phenotype), q² represents the frequency of the homo-zygous recessive genotype (cystic fibrosis phenotype), and 2pq represents the frequency of the heterozygous genotype (individuals that carry one copy of the CFTR mutant allele). Moreover, under Hardy-Weinberg equilibrium, the sum of the dominant 'p' allele frequency and the recessive 'q' allele frequency is equal to 1. In this case, we can observe that the frequency of the homo-zygous recessive condition for cystic fibrosis (q²) is 1/3200. In consequence, the frequency of the recessive allele for cystic fibrosis can be calculated as follows:

1/3200 = q² (have two CFTR mutant alleles) >>  

q = √ (1/3200) = 1/56.57 >>

- Frequency of the CFTR allele q = 1/56.57 = 0.0177  

- Frequency of the dominant 'normal' allele p = 1 - q = 1 - 0.0177 = 0.9823


Related Questions

It is observed that constipation is more common among people in the western countries who eat more meat and processed food than us. What could be the reason for this? What should be changed in their diet?
I already know this answer, just checking, it's cuz of roughage

Answers

Answer:

yes your answer is correct

Explanation:

Constipation happens when the colon absorbs too much water, this can occur if the muscles in the colon are contracting slowly or poorly, causing the stool to move too slowly and lose more water. As meat need much water to digest, so they leads to problem of constipation. Hence, they should eat sufficient amount of water to cure constipation.

Constipation is common among people in western countries who eat more meat and processed food because there is no enough roughage in their bodies which prevents constipation .Fruits and vegetables like like corn etc contains lot of roughage.

Answer:

hi here is your answer is that Constipation is common among people in western countries who eat more meat and processed food because there is no enough roughage in their bodies which prevents constipation .Fruits and vegetables like like corn etc cpntain lot of roughage

Explanation:

i hope this answer will help you

How does water relate to the ability of a living thing to generate usuable energy?

Answers

Answer:

Without the proper balance of water, chemical reactions in cells could not take place.

Explanation: :)

During the process of DNA replication, the whole molecule gets copied in the [A] phase of the cell cycle. The DNA strands are separated by the enzyme [B] while [C] keeps it from overwinding. The 2 strands are copied differently. The [D] strand is made continuously, while the [E] strand is synthesized in small sequences called Okazaki fragments. The main enzyme involved in DNA replication is [F]. This enzyme can only add nucleotides to an existing strand, so short sequences of [G] made by the enzyme [H] are needed for the process of elongation. In the [U] strand, the enzyme DNA polymerase one removes the short tj sequences and fills the gaps, while [K] joins the fragments.

Answers

Answer:

Synthesis, DNA helicase, topoisomerase, leading strand, lagging strand, DNA polymerase, nucleotides, primase, lagging strand, nucleotide, DNA ligase

Explanation:

During the process of DNA replication, the whole molecule gets copied in the synthesis or S phase of the cell cycle. The DNA strands are separated by the enzyme helicase while topoisomerase keeps it from overwinding. The 2 strands are copied differently. The leading strand is made continuously, while the lagging strand is synthesized in small sequences called Okazaki fragments. The main enzyme involved in DNA replication is DNA polymerase. This enzyme can only add nucleotides to an existing strand, so short sequences of nucleotides (primer) made by the enzyme primase are needed for the process of elongation. In the lagging strand, the enzyme DNA polymerase one removes the short tj sequences and fills the gaps, while DNA ligase joins the fragments.

A Synthesis,

B DNA helicase,

C topoisomerase,

D leading  

E lagging strand

F DNA polymerase

G nucleotides

H primase

I lagging strand

J nucleotide

K DNA ligase

Hi I'm pretty sure this is D just want to make sure :)


A population of snails is experiencing disruptive selection in terms of their shell patterns.

Which statement about the population is most likely true?


Two different shell patterns are combining into one very common pattern.

Snails with two different shell patterns are surviving in greater numbers than snails with the most common shell pattern.

Snails with a new shell pattern are surviving in greater numbers than snails with all other shell patterns.

Snails with the most common shell pattern are surviving in greater numbers than snails with all other shell patterns.

Answers

Answer:

Snails with the most common shell pattern are surviving in greater numbers than snails with all other shell patterns.

Explanation:

This is because of the natural selection process. The better adaption of the most common shell pattern makes it easier for the snails to survive the natural habitat.

Can someone help me with this pls

Which of the following results in agglutination?
(1) similar blood types being mixed
(2) the separation of blood cells from plasma
(3) antigens reacting to other antigens
(4) antibodies reacting to foreign antigens (5) the donation of blood to a blood bank​

Answers

Answer:

your answer is antibodies reacting to foreign antigens.

Answer: antibodies reacting to other antigens

it is usually measured in m/s​

Answers

Explanation:

The speed of light in vacuum is 299 792 458 meters per second. unit of acceleration is the meter per second per second (m/s2). unit of area is the square meter (m2).

...

Units of Length

10 millimeters (mm) = 1 centimeter (cm)

10 centimeters = 1 decimeter (dm)

10 centimeters = 100 millimeters

10 decimeters = 1 meter (m)

what is defferenciated cell and and undeferenciated cell.with example​

Answers

Answer:

Differentiated cells refer to the specialized cells in multicellular organisms modified to carry out a particular function, such as transporting a certain substance or executing a specific task, while undifferentiated cells refer to the stem cells capable of giving rise to indefinitely more cells of the same type,.

example of differentiated cell=zygote to embryo then a comlex foetusexample of undifferentiated cell= embryonic stem cell.

hope it helpsstay safe healthy and happy.

One true-breeding line of mice is obese and dark and another is lean and light. Dark is dominant to light, but obese and lean exhibit incomplete dominance. What proportion of offspring from a dihybrid cross should be both dark and intermediate between obese and lean

Answers

Answer:

6/16 Intermediate and dark ⇒ 2/16 OoDD + 4/16 OoDd

Explanation:

Due to technical problems, you will find the complete explanation in the attached files

Differentiate between pathogenicity and hypersensitivity; Also write different methods of inoculating the plants.

Answers

Answer:

As nouns the difference between pathogenesis and pathogenicity. is that pathogenesis is the origin and development of a disease while pathogenicity is the quality or state of being capable of causing disease.

explain what makes psychology a science.

Answers

Psychology is a science because it follows the empirical method. ... We can directly observe and carefully measure externals such as what a person does, says, and marks down on a psychological test. We cannot directly observe a person's mind (e.g., internal thoughts, emotions).

A 45-year-old woman named Christine is measured as having the following skinfold thicknesses on the right side of her body: Triceps: 14mm; Thigh: 32mm; Suprailium: 28mm. Estimate her body fat percentage.

Answers

Answer:

The skinfold method, the measurement of subcutaneous fat folds, is the most widely adopted field method for the assessment of body fat, especially in children.

It is based on the principle that fat is of a known density and by “summing” measurements of subcutaneous fat thickness across the body, total and regional fat can be estimated.

Skinfold thickness measurements are typically used to rank individuals in terms of relative total “fatness”, or to assess subcutaneous fat at various regions of the body.

Population specific equations are used to derive estimates of percent body fat.

In infancy, it might be the sole tool available for assessing body composition longitudinally as other methods may not be feasible, or may only be suitable for use at body sizes e.g. PEA POD, can only measure infants up to 10kg.

The most generally used field method for determining body fat, particularly in kids, is the skinfold method, which involves measuring subcutaneous fat folds.

What is skinfold method?

Skinfold method is defined as a method for determining how much body fat there is. It entails delicately pinching the skin and underlying fat in several locations using a tool called a caliper. To acquire precise findings using this quick and easy body fat estimation technique, a high level of competence is needed.

It is based on the idea that since subcutaneous fat thickness measurements may be "summed" to estimate total and regional fat because subcutaneous fat has a known density. Measures of skinfold thickness are widely used to categorize individuals based on their relative degrees of overall "fatness" or to assess subcutaneous fat in various bodily regions. Estimates of the percent body fat are derived using equations that are specific to a population.

Thus, the most generally used field method for determining body fat, particularly in kids, is the skinfold method, which involves measuring subcutaneous fat folds.

To learn more about skinfold method, refer to the link below:
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How is the evidence for the multi-regional theory of migration supported?

Answers

The main fossil evidence in support of the multiregional and candelabra hypotheses was the discovery of the Dali Man in China. ... Some genetic studies also offered support to a multiregional and candelabra models, inferring the origin of a few genetic loci outside of the African continent.

The most common Class II variant is the F508del variant, which is missing the 508th amino acid in the protein but has an otherwise normal sequence. Loss of this amino acid leads to misfolding of the protein, and the misfolded protein is not properly transported to the membrane. Based on this information, how many nucleotides are deleted in the CFTR allele encoding this variant?

Answers

Answer:

The correct answer is - 3 (two codons of 507th that are U, C, and the first nucleotide of 508th codon U).

Explanation:

Each amino acid is coded by a three-nucleotide base long codon. So in the case of the F508del variant, there is a deletion of three nucleotides that is encoded for phenylalanine amino acid.

In this isoleucine is encoded by 507th codon that is AUG and 508th codon is UUU codes for Isoleucine.

In this case, two codons of 507th are U, C, and the first nucleotide of 508th codon U. So overall three nucleotides are deleted in the F508del variant..

Senario: 2 years ago, a fruit was smuggled into California on a plane from an exotic, far away land. The homeowner saw that the fruit had maggots and tossed it into the backyard, hoping the seed would grow. The larvae hatched out and moved throughout the area. This fictitious insect will destroy fruit and has the possibility of spreading disease killing the trees. The insect consumes plants in the Prunus species of stone fruits? Look up the plant genus Prunus.

Discussion: The insect has spread over a large area of Southern California, discovered at UC Riverside. What steps would you do to control or eradicate the destructive exotic insect?

Answers

Answer:

To destroy this insect, a chemical should be used or made that will fight the main power of the insect. Also the food that is targeted should be removed.

Explanation:

Scientists think that red pandas and raccoons share a more recent common
ancestor than red pandas and giant pandas do. If this is true, what would you
expect to be true about the genetic sequences in these organisms?
O A. Red pandas and raccoons must have identical DNA sequences.
B. The DNA sequences of giant pandas are likely to be more similar
to the sequences of raccoons than of red pandas.
C. Red pandas must have a different genetic code than giant pandas.
O D. The DNA sequences of red pandas are likely to be more similar to
the sequences of raccoons than of giant pandas.

Answers

Answer:

D seems to be best answer if that was my test

Explanation:

makes the most sense

Answer:

D

Explanation:


3. In biological terms are you a
producer or a consumer? Explain
your answer.

Answers

Answer:

consumer

Explanation:

because we get things from living things

The following statement is incorrect as stated "Pesticides create pesticide resistance in mosquitoes." Rewrite this sentence so that it is a more accurate statement of what actually occurs when pesticides are used. Why is this concept important to know in trying to control outbreaks of mosquito transmitted diseases such as eastern equine encephalitis (also known as Triple E)?

Answers

Answer:

Mosquitoes usually become resistant to pyrethroids through the mutation of a sodium channel gene that controls the movement of ions across cell membranes. Mutations in a single gene are enough to make mosquitoes almost completely resistant to the level of pyrethroids used in insecticides.

Summarize the steps of Scientific method in one paragraph in your own words.

Answers

Answer:

Ask a question or identify a problem.Gather information and form a hypothesis.Create an experiment to test your hypothesis.Collect data and observations by doing/ performing the experiment. Draw a conclusion.Share your findings.

If you want as paragraph:

Ask a question or identify a problem. Gather information and form a hypothesis. Create an experiment to test your hypothesis. Collect data and observations by doing/ performing the experiment. Draw a conclusion. Share your findings.

Hope it helps!

Plz mark brainliest!

What is the correct sequence of events for the life cycle of the pork tapeworm, T. solium? Arrange the following statements in chronological order

Answers

Answer: See explanation

Explanation:

The correct sequence of events for the life cycle of the pork tapeworm, T. solium in chronological order will be:

• Eggs are produced by adult tapeworms living in definitive host

• Eggs are released in the environment in the faeces

• Pigs eat grass contaminated, or fertilized with human faeces.

• Inside the intermediate hosst, the eggs mature into larvae and encyst in the host muscles.

• The definitive host ingests the larvae and becomes infected.

In the experiment on stimulation of the isolated sciatic nerve, a compound action potential is produced. This represents _______

Answers

Answer: A summed electrical activity of all axons in the nerve

Explanation:

During the experiment with regards to the stimulation of the isolated sciatic nerve, a compound action potential is produced. It should be noted that this represents the summed electrical activity of all axons in the nerve.

Here, the summed electrical activity of all axons in the nerve represents the sum of the potentials that were recruited in the experiment.

What would be the most likely candidate for a complete transmembrane segment of a protein in the lysosomal membrane?

Answers

Answer:

Alpha-helical and beta-barrels.

Explanation:

Alpha-helical and beta-barrels are the types of transmembrane protein and both are most likely candidate for a complete transmembrane segment of a protein in the lysosomal membrane. A transmembrane protein (TP) is a type of membrane protein that spread in the whole cell membrane. Transmembrane proteins act as gateways that permit the transport of specific substances across the membrane of the cell.

Given the latitudinal differences in sunlight intensity, how might you expect the carrying capacity of a plant species found at the equator to compare with that of a plant species found at high latitudes? Explain your answer

Answers

Answer:

The carrying capacity of a plant species expect in the equator is higher as compared to the carrying capacity at high Latitudes. This is due to the equator the plants have more light available, so the ecosystem can give them better conditions to survive and reproduce. Remembering that the carrying capacity is the largest population size an ecosystem can support without degrading itself, in the equator would be higher as it can have better conditions of light, so they would survive and reproduce more and the largest population the ecosystem could support would be higher.

When the dry-bulb temperature is 22°C and the wet-bulb temperature is 13°C, the relative
humidity is
1. 10%
2. 33%
3. 41%
4. 59%

Answers

Answer:

33 percent is wright

hope it may help you

A food product was produced at room temperature (20°C) and its water activity was 0.3. Then it was shipped to a store and its temperature was 30°C during shipping, which of the following could happen?
a. The product water activity will increase
b. The water content of the product do not changed
c. The product may be spoiled faster than expected
d. All of the above

Answers

Answer:

Hence the correct answer is All of the above.

Explanation:  

With the rise in temperature, the water activity will increase and water movement between molecules will increase and this may allow the expansion of microorganisms leading to the spoilage of food.

When an organism encounters nitrate in its environment, which condition will determine whether the nitrate is used in an assimilatory or dissimilatory manner?

a. low concentration or ammonia
b. low concentration of sulfate
c. oxygen present
d. low temperature
e. oxygen absent
f. high concentration of nitrite

Answers

Answer:

Dissimilatory- oxygen absent

Assimilatory- high concentration of nitrite

Explanation:

In assimilatory nitrate reduction, ammonium is produced and subsequently incorporated into biomass to build up e.g., proteins and nucleic acids. Dissimilatory nitrate reduction is a process for energy conservation, in which nitrate is used as an electron acceptor in the (near) absence of oxygen . Dissimilatory nitrate reduction and nitrate storage in particular are physiological life traits that provide microbes with environmental flexibility (i.e., metabolic activity under both oxic and anoxic conditions) and resource independence (i.e., anaerobic metabolism without immediate nitrate supply), respectively. Such life traits are especially important in environments that are temporarily anoxic and/or nitrate-free and they may have developed as a “life strategy” in both prokaryotes and eukaryotes

what is the function of the liver?

Answers

Answer:

The Liver Stores Glycogen and Vitamins.

Its helps in Excreting Bilirubin which is produced from the breakdown of Red Blood Cell(RBC).

It also helps In the Production of Bile(This is stored in the gall bladder).

Ariella is a 12-year-old whose BMI-for-age is above the 95th percentile. What conclusion could be drawn? a. She is at risk for undernutrition b. Her body fat percentage is in an unhealthy range. c. She is going through a growth spurt. d. She is at risk for future obesity.

Answers

Answer:

She is at risk for future obesity

Explanation:

The correct conclusion could be drawn is she is at risk for future obesity. BMI is a body mass index that is derived from the mass and height of the person.

How BMI is calculated?

The formula is BMI = kg/m2

Where kg is a person’s weight in kilograms and m² their height in meters squared.

BMI categoriesUnderweight = <18.5Normal weight = 18.5–24.9Overweight = 25–29.9Obesity = BMI of 30 or greater

Thus, it is concluded that Ariella is at a risk for future obesity according to her BMI percentile.

Learn more about BMI here:

https://brainly.com/question/2064513

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Afferont neurons
a.transmit sensory input to the CNS
b.are multipolar neurons
c.have many dendrites and a single long axon
d.are found only within the brain and spinal cord

Answers

Answer:

a.transmit sensory input to the CNS

Explanation:

Afferent neurons will take input from your muscles, skin etc. and send it to your CNS (usually via spinal nerves).

When blood pH becomes overly acidic, respiration and kidney function change to bring the acidity back to its normal pH level of 7.4. What does this process best exemplify

Answers

Answer:

homeostasis

Explanation:

Homeostasis has to do with processes that maintain the internal balance within an organism. It can succinctly be defined as the process of regulating an organism's internal environment. The process of homeostasis is very important in the maintenance of important indicators of balance in the body such as body temperature, body pH, etc.

Hence, when blood pH becomes overly acidic, respiration and kidney function change to bring the acidity back to its normal pH level of 7.4. This is a homeostatic response.

Writing an Equation in Slope-Intercept Form
Q
Check
y
Determine the equation for the given line in
slope-intercept form
4
O y = -5x-1
=-1
2
X
-6
-4
-2
2
LO
O y = x+1
O y = 3x+1
O y=-x-1
-2
-4
Hint

Answers

Answer:

need a full picture plzzz

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