Brain cells, which depend on glucose for energy, use the glucose transporter GLUT3, which has a Km of 1.5mM. Liver cells, which store glucose (as glycogen) after a meal and release glucose between meals, use the glucose transporter GLUT2, which has a Km of 15mM. Calculate the rate (as a % of Vmax) of glucose uptake in brain cells and in liver cells at circulated glucose concentrations of 3mM (starvation), 5 mM (normal levels), and 7mM (after a carbohydrate-rich meal). Use this rearranged M-M equation.

Answers

Answer 1

Answer:

Explanation:

Given that:

The brain cell which uses glucose transporter GLUT3 Km = 1.5 mM

The liver cell which stores glucose GLUT2 Km = 15 mM

The objective is to calculate the rate (as % of Vmax) of glucose uptake in brain cells and liver cells under starvation conditions.

Using the M-M equation i.e Michaelis- Menten equation;

[tex]Rate = \dfrac{V_{max}* [S]}{[S]+K_m}[/tex]

By rearrangement

[tex]\dfrac{Rate}{V_{max}}= \dfrac{[S]}{[S]+K_m}[/tex]

where;

[tex]V_{max}[/tex] = maximum velocity of a reaction

Thus; the rate as a % of Vmax of glucose uptake in brain cells is calculated as:

[tex]\dfrac{Rate}{V_{max}}= \dfrac{[3 \ mM]}{[3 \ mM]+1.5 \ mM}[/tex]

[tex]\dfrac{Rate}{V_{max}}= \dfrac{3 \ mM}{4.5 \ mM}[/tex]

[tex]\dfrac{Rate}{V_{max}}=0.667[/tex]

[tex]\dfrac{Rate}{V_{max}}=66.7 \%[/tex]

the rate as a % of Vmax of glucose uptake in liver cells is calculated as:

[tex]\dfrac{Rate}{V_{max}}= \dfrac{[3 \ mM]}{[3 \ mM]+15 \ mM}[/tex]

[tex]\dfrac{Rate}{V_{max}}= \dfrac{3 \ mM}{18 \ mM}[/tex]

[tex]\dfrac{Rate}{V_{max}}=0.166[/tex]

[tex]\dfrac{Rate}{V_{max}}=17 \%[/tex]

Thus, the uptake is larger brain cells due to the fact that the brain cells GLUT3 have higher tendency to attract glucose.


Related Questions

which is smallest to largest form?
human tissue, human cell, bacterial cell, virus, human organ, human organ system.

Answers

Answer:

Explanation:

virus, bacterial cell, human cell, human tissue, human organ, human organ system.

The smallest to largest forms in the order:

VirusBacterial cellHuman cellHuman tissueHuman organHuman organ system.

The Virus comes first as it is much smaller than the Bacterial cell and can be

viewed with an electron microscope which has a higher magnification

Cells are the smallest unit of life and they aggregate to form tissues . The

tissues then aggregate to form organs and organs to organ system which is

why the human cell comes next followed by the Human tissue, Human organ

and lastly Human Organ systems.

Read more on https://brainly.com/question/18540902

True or false? An ecosystem includes all living things (producers, consumers, decomposers) in an area and their nonliving environment

Answers

Answer:

True

Explanation:

Answer:true

Explanation:

In subduction, what determines which plate will be on top and which will be on bottom?

Answers

the top plate will be on the top and the bottom plate will be on the bottom??? in subduction

The sodium-potassium pump is a specialized type of transport protein found in your cell membranes. The pump's
job is to move potassium ions into the cell in
the direction of low to high concentration. In order for this to happen, the cell uses energy
to operate the pump. This is an important step in the function of our
nerve cells. What type of transport does the sodium-potassium pump use?

A. Diffusion
B. Active Transport,
C. osmosis
D. Passive Transport

Answers

Answer:

Active Transport

Explanation:

Active Transport requires energy input

Please help I’ll cashapp and mark brainless

Answers

Answer:

d.

Explanation:

Making observations. :)

Answer:

b. testing hypothesis

Explanation:

what do you test in history and art, nothing

Which of the following elements is required for growth and development and is in our DNA? *
hydrogen
carbon
oxygen
nitrogen
phosphorus

PLEASE HELP

Answers

Answer:

Carbon hydrogen oxygen nitrogen

Explanation:

Phosphorus is also essential all these are essential for growth and our present in our DNA

a chain of volcanoes that develop parallel to a trench

Answers

Answer:

Offshore volcanoes form islands, resulting in a volcanic island arc. Generally, volcanic arcs result from the subduction of an oceanic tectonic plate under another tectonic plate, and often parallel an oceanic trench.

Explanation:

A membrane that allows some molecules to pass through but not others is called a(n)_____ _____ _____

Answers

has a selection function so it selects the substances which to enter or not inside the cell

during which phase of the cell cycle does most cell growth occur

Answers

Cell growth occurs constantly throughout interphase. S phase is the time when all the cell's chromosomes are replicated so significant cell growth occurs here, but during both G1 and G2 cell growth occurs.

hope this helps

During the interphase of the cell cycle most cell growth takes place.

What is cell cycle?

A cell cycle is the series of events that takes place in a cell as it grows as well as divides.

A cell spends the maximum of its time in what is referred to as interphase, where it grows, reproduces its chromosomes, along with prepares for cell division. The cell then exits interphase, goes through mitosis, and divides completely.

The cell cycle's longest phase is interphase. This is the stage at which the cell undergoes and duplicates its DNA before entering mitosis.

Chromosomes align, separate, and move into new daughter cells during mitosis. Because the prefix inter- means "between," interphase occurs between mitotic (M) phases.

Thus, the cell growth takes place in the interphase of the cell cycle, and the division takes place in the M-phase.

For more details regarding a cell cycle, visit:

https://brainly.com/question/15876101

#SPJ2

Which of the following is not a function of the cell membrane?
•It supports and shapes the cell.
•It assists in cell division.
•It positions organelles.
•It provides energy to the cell.

Answers

Answer:

A is the right answer

Explanation:

The cell wall is the outermost layer of the cell. It surrounds the cell membrane and provides these cells with structural support and definite shape. It prevents the over-expansion of the cell when water enters the cell.

Can I have brainliest

The mountains of the Sierra Nevada play a role in the formation of desert in eastern California and Nevada.

What is this an example of?

Answers

Answer:

The correct answer would be - The lithosphere influences the atmosphere and biosphere .

Explanation:

The mountains of the Sierra Nevada play the role of a barrier that blocks the air or wind that brings the clouds filled with water to eastern California and Nevada as it can not pass the mountains and reach the other side of mountains which cause less or no rain to this region.

Rain is a very important aspect for the region to be less diverse in plants and animals as most of them require water but as it is described there is no or very little precipitation so it becomes desert.

This makes it an example of the lithosphere influences the atmosphere and biosphere .

Do you think a magnitude 9.0 earthquake will generate a tsunami?

Answers

its possible but rare

Tell me a description of the urea in simple terms.

Answers

Answer:

Urea: A nitrogen-containing substance normally cleared from the blood by the kidney into the urine. Diseases that compromise the function of the kidney often lead to increased blood levels of urea, as measured by the blood urea nitrogen (BUN) test.

Herbivores obtain most of their energy by
A.consuming animals
B.consuming plants
C.producing sugar
B. absorbing sunlight

Answers

Answer: B.) Consuming plants


Herbivores consume and get their energy from only plants :)

..........become butterfly after pupa stage.


1-Caterpillar

2-egg

3-pupa

4-tadpole ​

Answers

Answer:

caterpillar

Explanation:

caterpillar become butterfly after pupa stage

Which of the following does not lead to an increase in phytoplankton reproduction?
a.
increased nutrient availability
b.
increased sunlight
c.
increased oxygen levels
d.
increased levels of carbon dioxide


Please select the best answer from the choices provided

A
B
C
D

Answers

Answer:

C. increased oxygen levels

Explanation:

edge 2020

How many time can you revive?

Answers

Answer:

0

we are not cats

0 we can’t revive, we don’t have 9 lives we have one.

Which is an outer planet?​

Answers

Saturn is an outer planet

Which of the following is not a current theory regarding global climate change? a. Global warming will stimulate crop growth. b. Even the moderate projections on global warming will cause devastation. c. Higher levels of carbon dioxide in the atmosphere will have no effect. d. Sea levels will rise as a result of global warming.

Please select the best answer from the choices provided A B C D

Answers

Answer:

c

Explanation:just took the test

Flooding has the potential to spread illness and harm infrastructure and ecosystems. Health problems can reduce worker productivity, raise mortality, and have an impact on the availability of food. Thus, option C is correct.

What is impact of global climate change on ecosystem?

Droughts that are more frequent and intense, storms, heat waves, rising sea levels, melting glaciers, and warming oceans can all directly harm animals.

Destroy the habitats they rely on for survival, and have a disastrous impact on people's way of life and communities. Dangerous weather events are increasing in frequency or severity as climate change gets worse.

Therefore, Higher levels of carbon dioxide in the atmosphere will have no effect. Food production and human health can be harmed by drought.

Learn more about climate change here:

https://brainly.com/question/12346202

#SPJ6

Fireflies emit light. The production of light by an organism is called bioluminescence. To generate visible light, cells in a firefly's tail produce thousands of luciferase enzymes. Luciferase binds to a chemical called luciferin. Once bound, the luciferase enzyme speeds up a chemical reaction that combines an oxygen molecule and luciferin to produce oxyluciferin. This reaction requires energy and releases light. Which of the following best describes how the luciferase enzyme speeds up the chemical reaction? F Luciferase increases the amount of time the light is visible. G Luciferase decreases the amount of energy required for the reaction to start. H Luciferase increases the number of sites on luciferin that must bind to oxygen. J Luciferase decreases the temperature of the environment inside the body of the firefly.​

Answers

Answer:

Fireflies emit light. The production of light by an organism is called bioluminescence. To generate visible light, cells in a firefly's tail produce thousands of luciferase enzymes. Luciferase binds to a chemical called luciferin. Once bound, the luciferase enzyme speeds up a chemical reaction that combines an oxygen molecule and luciferin to produce oxyluciferin. This reaction requires energy and releases light. Which of the following best describes how the luciferase enzyme speeds up the chemical reaction?

Explanation:

b

The description that best describes how the luciferase enzyme speeds up the chemical reaction is - Luciferase decreases the amount of energy required for the reaction to start.

Fireflies generate a chemical reaction that allows their body to emit light, inside their body. This light generation is called bioluminescence. This process involves various steps:

Oxygen binds with calcium, luciferin chemical with ATP to make oxyluciferin.In the body of fireflies, there is the production of an enzyme called luciferase.This chemical reaction takes place in presence of luciferase that speeds up this reaction by decreasing the activation energy of the reaction.At the end of the reaction body of fireflies light up.

Thus, the correct answer is - Luciferase decreases the amount of energy required for the reaction to start.

Learn more about bioluminescence:

https://brainly.com/question/8897369

Interpret each rule of Kartilya ng Katipunan in one word ​

Answers

Answer:

Throughout the clarification category below, the definition including its query is mentioned.

Explanation:

The Kartilya ng Katipunan acted as either the reference book or field guide for the organization's new representatives, which set out other principles and expectations including its party. Emilio Jacinto published the first version of Kautilya. The revamped Decalogue was later published by Andrés Bonifacio. It would never be released although Bonifacio thought that Kartilya of Jacinto seemed equivalent to what he has already created.

How many atoms of oxygen are in the formula for 2 hydrogen peroxide? 2H202

Answers

There are 2oxygen atoms

Answer:

The mass of hydrogen peroxide, H2O2 would be calculated like this: H2O2 has 2 hydrogen atoms and 2 oxygen atoms in it. So one molecule of hydrogen peroxide weighs in at 34.02 u.

Explanation:

pretty self explanatory.

A big body of land on the globe?

Answers

russia is huge so russia and the places around there

which homeostasis mechanism is the plant version of an animal drinking when it gets thirsty?

A ) a plant wilting when soil dries out
B ) a plant making sugar through photosynthesis
C ) a plant's growth response toward light
D )a plant's growth response to gravitation​

Answers

A) a plant wilting when soil dries out.

Which of the following best describes giant stars? A. hot, dim stars B. cool,dim stars C. hot ,bright stars D. cool, bright stars

Answers

Answer:

C hot bright stars

Explanation:

they are literally hot burning balls of bright gas

Answer:

It is the answer C

:)

acer saccharum scientific name for the sugar maple tree acer is the name of the trees?

A.genus
B.phylum
C.species
D.kingdom

Answers

Genus comes first so genus

What is the ratio of hydrogen and oxygen in all carbohydrates when compare to carbon ____hydrogen: _____oxygen

Can anyone tell me this ?

Answers

Answer:

n(C1H2O1)

Explanation:

Think of glucose, which is C6H12O6.  In the case of glucose, n would be 6.

What are some questions that scientists on Earth might study? Choose all that apply.

A. How Weather & Climate systems affect Earth?
B. How can Earthquake be detected?
C. How does light travels through optical fibers?
D. Is water found on other planets?

Answers

Answer:

A,B,C

Explanation:

It won't be D. because you would need to study or go to the other planets to answer the question.

Hope this helps!

The excretory system disposes waste through the stomach.

True or False?

Answers

Answer:

False.

Explanation:

Actually the stomach isn't part of the excretory system, it's part of the digestive system.  The organs of the excretory system include the kidneys, large intestine, liver, skin, and lungs. The kidneys (also part of the urinary system) filter out blood from waste. The large intestine's job is to eliminate solid waste that remains after food is digested and water is extracted from the indigestible matter.  The liver breaks down many substances in the blood, including toxins. Sweat glands in the skin secrete a fluid waste called sweat or perspiration; however, its primary functions are temperature control and pheromone release. The lungs (also in the respiratory system) excrete some waste products, such as carbon dioxide and water.

Hope this helps!

Which of the following is an example of diffusion?
A water freezing into ice
B sugar dissolving in a glass of water
C rain falling from the sky
D a stone sinking to the bottom of a lake

Answers

The answer is B, because the sugar is moving down a concentration gradient.
Other Questions
Solve each equation by factoring.When finding the solutions for `15k^2+k-4=-2`, what are the correct steps? The most massive automobile to have been manufactured on a regular basiswas the Russian-made Zil-41047. If one of these cars was to move at just8.9 m/s, its momentum would be 2.67 x 10^4kg m/s. Use this informationto calculate the mass of a Zil-41047. WILL GIVE MORE POINTS IF YOU ANSWER ALL MY QUESTIONS CORRECTLY (500 points plus 10 for each other question)Every morning I lay on the floor in the front parlor watching her door. The blind was pulled down to within an inch of the sash so that I could not be seen. When she came out on the doorstep my heart leaped. I ran to the hall, seized my books and followed her. I kept her brown figure always in my eye and, when we came near the point at which our ways diverged, I quickened my pace and passed her. This happened morning after morning. I had never spoken to her, except for a few casual words, and yet her name was like a summons to all my foolish blood.Her image accompanied me even in places the most hostile to romance. On Saturday evenings when my aunt went marketing I had to go to carry some of the parcels. We walked through the flaring streets, jostled by drunken men and bargaining women, amid the curses of labourers, the shrill litanies of shop-boys who stood on guard by the barrels of pigs cheeks, the nasal chanting of street-singers, who sang a come-all-you about ODonovan Rossa, or a ballad about the troubles in our native land. These noises converged in a single sensation of life for me: I imagined that I bore my chalice safely through a throng of foes. Her name sprang to my lips at moments in strange prayers and praises which I myself did not understand. My eyes were often full of tears (I could not tell why) and at times a flood from my heart seemed to pour itself out into my bosom. I thought little of the future. I did not know whether I would ever speak to her or not or, if I spoke to her, how I could tell her of my confused adoration. But my body was like a harp and her words and gestures were like fingers running upon the wires.One evening I went into the back drawing-room in which the priest had died. It was a dark rainy evening and there was no sound in the house. Through one of the broken panes I heard the rain impinge upon the earth, the fine incessant needles of water playing in the sodden beds. Some distant lamp or lighted window gleamed below me. I was thankful that I could see so little. All my senses seemed to desire to veil themselves and, feeling that I was about to slip from them, I pressed the palms of my hands together until they trembled, murmuring: O love! O love! many times.At last she spoke to me. When she addressed the first words to me I was so confused that I did not know what to answer. She asked me was I going to Araby. I forgot whether I answered yes or no. It would be a splendid bazaar, she said she would love to go.And why cant you? I asked.While she spoke she turned a silver bracelet round and round her wrist. She could not go, she said, because there would be a retreat that week in her convent. Her brother and two other boys were fighting for their caps and I was alone at the railings. She held one of the spikes, bowing her head towards me. The light from the lamp opposite our door caught the white curve of her neck, lit up her hair that rested there and, falling, lit up the hand upon the railing. It fell over one side of her dress and caught the white border of a petticoat, just visible as she stood at ease.Its well for you, she said.If I go, I said, I will bring you something.What innumerable follies laid waste my waking and sleeping thoughts after that evening! I wished to annihilate the tedious intervening days. I chafed against the work of school. At night in my bedroom and by day in the classroom her image came between me and the page I strove to read. The syllables of the word Araby were called to me through the silence in which my soul luxuriated and cast an Eastern enchantment over me. I asked for leave to go to the bazaar on Saturday night. My aunt was surprised and hoped it was not some Freemason affair. I answered few questions in class. I watched my masters face pass from amiability to sternness; he hoped I was not beginning to idle. I could not call my wandering thoughts together. I had hardly any patience with the serious work of life which, now that it stood between me and my desire, seemed to me childs play, ugly monotonous childs play.What is suggested by the interaction between the boy and the girl?A. a dearth of friends for both the boy and the girlB. a conflict between the boy and the girlC. an unrecognized attraction between the boy and the girlD. a disconnect between the boys dream and the reality of the situationE. a discomfort with public displays of affectionThe word annihilate in the second sentence of paragraph 9 is used to imply that the boyA. will destroy anything in his reachB. feels empowered and anxiousC. has been defeated by the world around him D. has conquered his feelings for the girlE. will rebel against his aunt The role of the GeneralAssembly is to make lawsfor this branch OfState governmentwhich branch is that? legislative, judicial, or executive what does the second row of numbers represents.help!!! please help me.! please i need help badly! How does alecs arrival at the cabin affect the events of the story? why did Nestorian graves have Chinese zodiac symbols on them How would you expand this model to include the effects of fishing on this population? Drag the tiles to the correct boxes to complete the pairs. Match the terms and practices with the ideas they represent. burial tombs oracle bones filial piety belief in afterlife arrowRight respecting parents and elders arrowRight communicating with ancestors arrowRight Which statement best describes how the structure of the judicial branch affects its interpretation of the Constitution?The system of federal courts and a Supreme Court may give the judicial branch multiple opportunities to interpret the Constitution.The system of federal courts and a Supreme Court give the judicial branch only one opportunity to interpret the Constitution.The system of federal courts and a Supreme Court force the judicial branch to answer to the executive branch.The system of federal courts and a Supreme Court force the judicial branch to answer to the legislative branch. how do you simplify this? What is the solution to the equation 13.7y = 6.2y + 30 14) -8p - 34 = 6p + 50 Find the acceleration if the change in velocity is 5 m/s and the time is 10 seconds Two major differences between Anglo-American settlers and Mexican settlers in Texas at this time werea. attitudes about plantation farming and cattle ranchingb. attitudes about slavery and governmentC. attitudes about language and educationd. attitudes about land grants and religion Which text structure would an author most likely use if the main purpose of the text is to identify the events ofWorld War I in the order in which they occurred?O cause-effectO problem-solutionO sequenceO description ayooo I need help ASAP Why was there a Constitutional Convention and how did it change the relationship between state and country? Answer in a full paragraph. The English imposed taxes on the colonies as a result of this war, which they fought with other European countries: