Autism and Maternal Antidepressant Use A recent study41 compared 298 children with Autism Spectrum Disorder to 1507 randomly selected con- trol children without the disorder. Of the children with autism, 20 of the mothers had used antidepres- sant drugs during the year before pregnancy or the first trimester of pregnancy. Of the control children, 50 of the mothers had used the drugs.
(a) Is there a significant association between prena- tal exposure to antidepressant medicine and the risk of autism? Test whether the results are sig- nificant at the 5% level.
(b) Can we conclude that prenatal exposure to antidepressant medicine increases the risk of autism in the child? Why or why not?

Answers

Answer 1

Answer:

(a) We conclude that there is a significant association between prenatal exposure to antidepressant medicine and the risk of autism at 5% significance level.

(b) Yes, we can conclude that prenatal exposure to antidepressant medicine increases the risk of autism in the child.

Step-by-step explanation:

We are given that Autism and Maternal Antidepressant Use A recent study 41 compared 298 children with Autism Spectrum Disorder to 1507 randomly selected control children without the disorder.

Of the children with autism, 20 of the mothers had used antidepressant drugs. Of the control children, 50 of the mothers had used the drugs.

Let [tex]p_1[/tex] = proportion of mothers who had used drugs having Autism Spectrum Disorder in their children.

[tex]p_2[/tex] = proportion of mothers who had used drugs not having Autism Spectrum Disorder in their children.

(a) Null Hypothesis, [tex]H_0[/tex] : [tex]p_1=p_2[/tex]      {means that there is no significant association between prenatal exposure to antidepressant medicine and the risk of autism}

Alternate Hypothesis, [tex]H_A[/tex] : [tex]p_1\neq p_2[/tex]     {means that there is a significant association between prenatal exposure to antidepressant medicine and the risk of autism}

The test statistics that would be used here Two-sample z test for proportions;

                         T.S. =  [tex]\frac{(\hat p_1-\hat p_2)-(p_1-p_2)}{\sqrt{\frac{\hat p_1(1-\hat p_1)}{n_1}+\frac{\hat p_2(1-\hat p_2)}{n_2} } }[/tex]  ~ N(0,1)

where, [tex]\hat p_1[/tex] = sample proportion of mothers who had used drugs having Autism Spectrum Disorder in their children = [tex]\frac{20}{298}[/tex] = 0.067

[tex]\hat p_2[/tex] = sample proportion of mothers who had used drugs not having Autism Spectrum Disorder in their children = [tex]\frac{50}{1507}[/tex] = 0.033

[tex]n_1[/tex] = sample of children with Autism Spectrum Disorder = 298

[tex]n_2[/tex] = sample of children without Autism Spectrum Disorder = 1507

So, the test statistics  =  [tex]\frac{(0.067-0.033)-(0)}{\sqrt{\frac{0.067(1-0.067)}{298}+\frac{0.033(1-0.033)}{1507} } }[/tex]

                                       =  2.281

The value of z test statistics is 2.281.

Now, at 5% significance level the z table gives critical values of -1.96 and 1.96 for two-tailed test.

Since our test statistic doesn't lie within the range of critical values of z, so we have sufficient evidence to reject our null hypothesis as it will fall in the rejection region due to which we reject our null hypothesis.

Therefore, we conclude that there is a significant association between prenatal exposure to antidepressant medicine and the risk of autism.

(b) Yes, we can conclude that prenatal exposure to antidepressant medicine increases the risk of autism in the child because if we reconsider our hypothesis for one-tailed test in which the null hypothesis states that the prenatal exposure to antidepressant medicine does not increases the risk of autism in the child.

For this hypothesis also, our test statistics will be more than the critical value of z and due to which we reject our null hypothesis and conclude that prenatal exposure to antidepressant medicine increases the risk of autism.


Related Questions

if I paid 38 dollars for 2800 apples how much would one cost me​

Answers

Answer:

Step-by-step explanation:

Answer:

$73.68

Step-by-step explanation:

2800 divide by 38 equals 73.68

Find the area of the rectangle ABCD. I need both green and grey box please.

Answers

Answer:

180

Step-by-step explanation:

12x15=180

Area = base x height
Area = 15 in. x 12 in.
Area = 180 inches squared
180 would be the green box and a 2 would go in the grey box

A local aquarium is filled halfway with water. How many cubic inches of water are in the aquarium?

Answers

Answer:

The aquarium contains [tex]\frac{x}{2}[/tex] cubic inches of water

Step-by-step explanation:

Given: A local aquarium is filled halfway with water.

To find: Volume of water in the aquarium

Solution:

Volume refers to the three-dimensional space enclosed by a boundary. S.I. unit of volume is [tex]m^3[/tex]

Let x cubic inches denotes volume of an aquarium.

As a local aquarium is filled halfway with water,

the aquarium contains [tex]\frac{x}{2}[/tex] cubic inches of water.

Answer:

Step-by-step explanation:

Showing results for The aquarium contains cubic inches of waterStep-by-step explanation:Given: A local aquarium is filled halfway with water.To find: Volume of water in the aquarium Solution:Volume refers to the three-dimensional space enclosed by a boundary. S.I. unit of volume is Let x cubic inches denotes volume of an aquarium.As a local aquarium is filled halfway with water,the aquarium contains cubic inches of water.

A square has side length of 9 which is the following a correct way to find the area of the square

Answers

Answer:

b means one of the sides of a square it doesn't matter because all sides are the same

Formula for a square is

b^2 or b*b

week. After 5 weeks the account holds $170. Write an equation that represents the amount y
(in dollars) of money in the account after x
weeks.

Answers

5x=170 that’s the answer

plss help find how much paint will be needed to paint the jewelry box?

Answers

Answer:

135

Step-by-step explanation:

volume = width*length*height

5*9*3=135

we need 135inches³ to paint it

135inches cubed paint should be needed

What are the solutions of this quadratic equation? 4x^2 + 3 = 4x + 2

Answers

Answer:

The answer is ±0.5 or ±1/2

Step-by-step explanation:

When you solve by using the quadratic formula, you get double roots that will solve the equation. Hope this helps!!

The solution of the quadratic equation is 1/2 and 1/2.

We have to find, the solution of the quadratic equation is [tex]4x^2 + 3 = 4x + 2[/tex].

To determine the solution of the quadratic equation following all the steps given below.

Equation; [tex]4x^2 + 3 = 4x + 2[/tex]

Step1; The equation is written in the standard form of the quadratic equation.

        [tex]4x^2 + 3 = 4x + 2\\\\4x^2 + 3 - 4x - 2=0\\\\4x^2 -4x +1 =0[/tex]

Step2; Factorize the equation for finding the solution of the equation,

                    [tex]\rm 4x^2-4x +1 = 0\\\\4x^2-2x -2x + 1= 0\\\\2x(2x-1) - 1 (2x-1)=0\\\\(2x-1) ( 2x-1) = 0[/tex]

Step3; The solution for the equation is,

                    [tex]\rm 2x- 1= 0 , \ 2x = 1 , \ x = \dfrac{1}{2}\\\\And \ 2x- 1= 0 , \ 2x = 1 , \ x = \dfrac{1}{2}\\\\[/tex]

Hence, The required solution of the equation is 1/2 and 1/2.

For more details refer to the link given below.

https://brainly.com/question/19776811

         

help asap !! will get branliest.​

Answers

The square root of 4 is 2. Since 3 is less than 4, the square root of 3 would be just under 2.

The first graph would be correct.

In ΔCDE, the measure of ∠E=90°, DC = 5, CE = 4, and ED = 3. What ratio represents the sine of ∠C?

Answers

Answer:

As E is right angle , CD is hypotenuse , and ED is perpendicular and CE is the base .

Thus sinC = Perpendicular/ Hypotenuse

sinC = ED/CD

sinC = 3/5

The sine of an angle in a right triangle is the ratio of the side opposite to

the angle to the hypotenuse side.

[tex]\underline{sin\angle C \ is \ \dfrac{3}{5}}[/tex]

Reasons:

The given parameters of ΔCDE are;

∠E = 90°, DC = 5, CE = 4, ED = 3

Required: The ratio that represents the sine of ∠C

Solution:

Given that ∠E = 90° therefore;

ΔCDE is a right triangle

DC = The hypotenuse side = 5

ED = 3 = The side opposite ∠C

[tex]sin\angle C = \mathbf{\dfrac{Opposite \ leg \ length}{Hypotenuse \ length}}[/tex]

Therefore;

[tex]\underline{sin\angle C \ is \ \dfrac{3}{5}}[/tex]

Learn more about trigonometric ratios here:

https://brainly.com/question/4232719

Determine whether the set of vectors is orthonormal. If the set is only​ orthogonal, normalize the vectors to produce an orthonormal set.Bold u 1 equals [Start 3 By 1 Matrix 1st Row 1st Column one third 2nd Row 1st Column one third 3rd Row 1st Column one third EndMatrix ]and Bold u 2 equals [Start 3 By 1 Matrix 1st Row 1st Column negative one half 2nd Row 1st Column 0 Subscript font size decreased by 6 Superscript font size decreased by 6 3rd Row 1st Column one half EndMatrix ]

Answers

Answer:

(i) See attached image file

(ii) Option A

Step-by-step explanation:

See attached image file

standard form of y=-3 (x-2)²​

Answers

Answer:

y = [tex]-3x^2+12x-12[/tex]

Step-by-step explanation:

(x-2)^2 = (x-2)(x-2) => [tex]x^2-4x+4[/tex]

now, multiple every term by negative 3 and you get...

-3x^2+12x-12

Use the information in the illustration to find the distance from the boathouse to the cabin. Round your answer to the nearest yard.

Answers

Answer:

The distance from the boathouse to the cabin = 50 yd (nearest yard)

Step-by-step explanation:

The question is incomplete.

Question:

To find the distance from the

boathouse on shore to the cabin on the island, a surveyor measures from the boathouse to point X as shown. He then finds m∠X with an instrument called a transit. Use the surveyor’s

measurements to find the distance from the boathouse to the cabin.

Find attached the diagram of the question.

Solution:

Let the distance from the boathouse to the cabin = y

the distance from the boathouse to the point X = 30yard

Find attached the diagram for the solution.

From the diagram, the triangle is a right angled triangle

Opposite = y

Adjacent = 30yd

∠X = 59°

Using trigonometry (SohCahToa)

We would apply Toa since adjacent is given and we are looking for opposite

tan θ = opposite/adjacent

tan 59° = y/30

y = 30 tan 59

y = 30(1.6643)

y = 49.929

y = 50 yd (nearest yard)

The distance from the boathouse to the cabin = 50 yd (nearest yard)

the perimeter of a rectangle is 20 units. The length of the rectangle is the distance from(-2,6) to (5,6) What is the width in units of the rectangles?

Answers

Answer:

3 units.

Step-by-step explanation:

We can calculate the length, since it only moves on the "x" axis, since on the "y" axis, it remains the same.

We know that between -2 to 5, there are 7 units. 2 + 5 = 7.

Therefore this would be the length.

We know that the perimeter is equal to:

p = 2 * w + 2 * l

P = 20

20 = 2 * w + 2 * 7

2 * w = 20 - 14

w = 6/2

w = 3

therefore, the width value is 3 units.

Answer:

3

Step-by-step explanation:

Dr. Gonzalez is considering joining the Garden Club. If he pays a $25 membership fee, he
can buy rosebushes from the club at a reduced price of $10 each. If he does not join the
club, he can buy rosebushes from a local nursery for $15 each. The graph below compares
the cost of buying rosebushes from the Garden Club and from the local nursery.

Answers

Answer:

In the Garden Club the cost will be a fixed fee of $25 and $10 for each rosebush, so if he buys X rosebushes, the total cost will be:

C1(X) = $25 + $10*X

While in the local nursery there is no initial cost, and each rosebush costs $15, so if he buys X rosebushes, the total cost will be:

C2(X) = $15*X

Now, let's find the value of X where C1 and C2 are equal, this is:

$25 + $10*X = $15*X

$25 = $15*X - $10*X = $5*X

X = 25/5 = 5

This means that if he buys 5 rosebushes, he will pay the same amount in both places.

If he buys less than 5 rosebushes, he will pay less in the local nursery (as it has a bigger slope, but no initial fee)

If he buys more than 5 rosebushes, he will pay less in the Garden club (because it has a smaller slope)

Can anyone help with these three questions will give 25 points

Answers

Answer:

Step-by-step explanation:

1). y + 2x < 6

  (y + 2x) - 2x < 6 - 2x

   y < -2x + 6 [Slope intercept form of the inequality]

2). y + 2x < 6

  Since there is no sign of equal to (=) in the given inequality therefore, line graphed will be dashed.

Notation of less than (<) denotes the area down the line.

Option (4) will be the answer.

3). y + 2x < 6

    x ≤ 2

Please find the graph attached.

2 cars departed the same place at the same
time. They traveled the same direction. One
traveled 50 mph for 4 hours. The other car
traveled 60 mph for 8 hours. How many miles
farther did the 2nd car travel?

Answers

200 miles and 480 miles so the answer would be the second car travelled 280 miles further

Arionna claims that since there are 3 feet in a yard, there are 9 cubic feet in a cubic yard. Which statement about her claim is true?
a.)Arionna is correct because there are 3 feet across the length of a cubic yard and 3 feet across the depth of a cubic yard. 3 times 3 = 9
b.)Arionna is correct because there are 3 feet in a yard and there are 3 dimensions in a cubic yard: length, depth, and height. 3 times 3 = 9
c.)Arionna is incorrect. There are only 3 cubic feet in a cubic yard because there are 3 feet in a yard, and the proportion will remain constant.
d.) Arionna is incorrect. There are 27 cubic feet in a cubic yard because a cubic yard is a prism with dimensions 3 ft Times 3 ft Times 3 ft. A prism with those dimensions will take 27 cubes to fill it if each cube is a unit cube of 1 ft.

Answers

Answer:

  d.)  Arionna is incorrect. There are 27 cubic feet in a cubic yard because a cubic yard is a prism with dimensions 3 ft times 3 ft times 3 ft. A prism with those dimensions will take 27 cubes to fill it, if each cube is a unit cube of 1 ft³.

Step-by-step explanation:

There are (3 ft)(3 ft) = 9 ft² in one square yard. To find the volume of a cubic yard, you need to multiply that by 3 ft again: (9 ft²)(3 ft) = 27 ft³.

_____

Additional comment

For many problems involving units, I like to keep the units with the numbers. That helps ensure the math is done correctly. In this problem, simply multiplying ft by ft gives ft^2, not ft^3, so you know right away that you haven't computed volume correctly.

PLEASE HELP!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!1

Answers

Answer:

ooga booga ooga booga ooga booga ooga booga ooga booga

Step-by-step explanation:

According to the picture, whats the answer?

Answers

Answer:

  126 in^2

Step-by-step explanation:

The surface area can be found from the surface area formula:

  SA = 2(LW +LH +WH)

I like to rearrange it slightly to ...

  SA = 2(LW +H(L +W))

For the given dimensions, the area is ...

  SA = 2(6·3 + 5(6 +3)) = 2(18 +45) = 126 . . . . square inches

Match the following items by evaluating the expression for x = -3.

Answers

Answer:

1/9-1/31-39

Step-by-step explanation:

x^-2 = (-3)^-2 = 1/(-3)^2 = 1/9

Each of the following is the previous value multiplied by -3,

x^-1 = x(x^-2) = (-3)(1/9) = -1/3

x^0 = x(x^-1) = (-3)(-1/3) = 1

x^1 = -3(1) = -3

x^2 = -3(-3) = 9

Mariko is training for a race and now runs 6.5 miles in about 52 minutes. Write an equation to represent the number of minutes, n, she will take to run m miles at this rate.

Answers

Answer:

52+n=m

Step-by-step explanation:

Answer:

6.5 /52 m = n

Step-by-step explanation:

The rate is 6.5 miles / 52 minutes

We are going to run m miles in n minutes

m = 6.5 / 52 * n

We want to solve for n

Multiply each side by 52/ 6.5

6.5 /52 m = 6.5 / 52 * n * 6.5 / 52

6.5 /52 m = n

A major home improvement store conducted its biggest brand recognition campaign in the company's history. A series of new television advertisements featuring well-known entertainers and sports figures was launched. A key metric for the success of television advertisements is the proportion of viewers who "like the ads a lot." A study of 1,189 adults who viewed the ads reported that 230 indicated that they "like the ads a lot." The percentage of a typical television advertisement receiving the "like the ads a lot" score is believed to be 22%. Company officials wanted to know if there is evidence that the series of television advertisements are less successful than the typical ad (i.e. if there is evidence that the population proportion of "like the ads a lot" for the company's ads is less than 0.22) at a 0.01 level of significance. 1) State H subscript 0 and H subscript 1. (2 points) 2) What critical value should the company officials use to determine the rejection region? (2 points) 3) What is the value of the test statistic? (4 points) 4) What is the conclusion of the hypothesis test? Is there evidence that the population proportion of "like the ads a lot" for the company's ads is less than 0.22?

Answers

Answer:

Step-by-step explanation:

Identify:      Hypothesized π = 0.22 n =1189 X = 230  

Estimate the sample proportion, p, of defective items. p= X/n = 230/1189 = 0.1934

List the formula for the standard error of a proportion.   [tex]\sqrt{PQ/n}[/tex]

Estimate the standard error of a proportion.  [tex]\sqrt{PQ/n} = \sqrt{0.22\times 0.78/1189} = 0.0120[/tex]

State the null and alternative hypotheses below.

H0: P = 0.22

H1: P<0.22

Illustrate the acceptance and rejection regions of the diagram to the right.

check the attached image below for the diagram

Identify the critical Z , -1.645

Fornulate the decision rule and list below.

If Z calculated is less than Z critical we reject null hypothesis

Calculate your test statistic.

[tex]Z= \frac{p-P}{\sqrt{PQ/n}} = \frac{0.1934-0.22}{0.0120}= -2.217[/tex]

Do you accept or reject the null hypothesis at 0.05 level of significance? Reject

State your conclusion. Should the quality control manage accept the shipment or return it?

WE have sufficient evidence that the population proportion of "like the ads a lot" for the company's ads is less than 0.22 at a 0.05 level of significance.

If a 0.01 level of significance had been used in the test, would you have accepted or rejected the null hypothesis?  

at 0.01 level of significance the critical value of Z is -2.33

Since Z calculated is greater than Z critical value we accept the null hypothesis

Which of the following choices represents the expanded form of the number 38,072?
30,000 + 800 + 70 + 2
30,000 + 8,000 + 70 + 2
30,000 + 8,000 + 700 + 2
3,000 + 800 + 70 + 2

Answers

Answer:

The second one.

Step-by-step explanation:

The others don't add up to that number

turn to passive voice the child chose the hat

Answers

Answer:

The hat was chosen was the child.

Step-by-step explanation:

When a radius intersects a chord of a circle at a right angle, what conclusion can be made?


The radius is bisected.

The chord is bisected.

The radius and the chord are congruent.

The radius is twice as long as the chord.

Answers

Answer:

The chord is bisected

Step-by-step explanation:

This problem seek our knowledge  on the mensuration of flat shapes, a circle.

The chord of a circle is a segment whose endpoints are on the circle. when a perpendicular bisector ( the radius) of any chord passes through the center of the chord at right angle to the chord, the chord is bisected into two. This is a way or could give us a good way to find the center of any circle.

     kindly find attached a diagram for your reference

Answer:

B

Step-by-step explanation:

Convert 475 milliliter to liters.

Answers

0.475

1000 milliliters is equal to 1 liter

Answer: 0.475 Liters

Step-by-step explanation: So, we know one liter is exactly 1,000 milliliters...therefore this would have to be a decimal.

Therefore, 475 milliliters to liters would be 0.475 liters.

hey can you guys help me with this? thx a lot! <3
Choose the answer based on the most efficient method as presented in the lesson.
If the first step in the solution of the equation -x + 6 = 5 - 3x is "subtract 5," then what should the next step be?

add x
add 3x
subtract 6

Answers

Answer:

add x

Step-by-step explanation:

get the constants on one side, and the variables on the other for easiest solving.

Pictures of students were asked how far they lived from my school that the table below shows the distance in miles which statement best compares the mean distance is for the two groups

Answers

Answer:

Group A (distance in miles) 1, 1.5, 3.03, 3.2, 2.8, 1.5, 1.8, 2.5, 2.2) Group B (distance in miles) 2, 2.5, 3.23, 1.3, 1.8, 2.4, 3, 1.5, 1.8)Therefore, the correct answer is A) It is equal for Group A and Group B.

find the perimeter of a circle whose diameter is 7 cm​

Answers

Find the perimeter of the circle is the same as finding the circumference of the circle.

Circumference Formula: C = 2πr

Divide the diameter by 2 to find the radius.

7 / 2 = 3.5

Solve using the given values.

C = 2(3.14)(3.5)

C = 2(10.99)

C = 21.98

Therefore, the circumference (perimeter) of the circle is 21.98cm²

Best of Luck!

The local supermarket buys lettuce each day to ensure really fresh produce. Each morning any lettuce that is left from the previous day is sold to a dealer that resells it to farmers who use it to feed their animals. This week the supermarket can buy fresh lettuce for $4.00 a box. The lettuce is sold for $10.00 a box and the dealer that sells old lettuce is willing to pay $1.50 a box. Past history says that tomorrow's demand for lettuce averages 250 boxes with a standard deviation of 34 boxes. Required: How many boxes of lettuce should the supermarket purchase tomorrow

Answers

Given Information:

Cost price = $4

Selling price = $10

Salvage value = $1.50

Average demand = μ = 250 boxes

Standard deviation = σ = 34 boxes

Required Information:

Number of lettuce boxes = ?

Answer:

The supermarket should purchase 268 boxes  of lettuce

Step-by-step explanation:

The required number of lettuce boxes that supermarket should purchase is given by

Number of lettuce boxes = μ + (z*σ)

Where μ is the average demand of lettuce boxes, σ is the standard deviation, and z is the z-score which is given by

p = C_us/(C_us + C_os)

The z-score corresponding to probability p will be obtained.

The cost of under stocking is given by

C_us = Selling price - Cost price

C_us = $10 - $4

C_us = $6

The cost of over stocking is given by

C_os = Cost price - Salvage value

C_os = $4 - $1.50

C_os = $2.50

p = C_us/(C_us + C_os)

p = 6/(6 + 2.50)

p = 0.7058

p  = 70.58%

The z-score corresponding to 70.58% probability is approximately 0.54

Number of lettuce boxes = μ + (z*σ)

Number of lettuce boxes = 250 + (0.54*34)

Number of lettuce boxes = 250 + (18.36)

Number of lettuce boxes = 268.36

Number of lettuce boxes ≈ 268

Therefore, the supermarket should purchase 268 boxes of lettuce.

How to use z-table?

Step 1:

In the z-table, find the probability you are looking for and note down the two-digit number of the given row. (e.g 0.5, 2.2, 0.5 etc.)

Step 2:

Then look up at the top of z-table and note down the value in the column for the remaining decimal point in the range of 0.00 to 0.09.

Step 3:

Finally, add the numbers obtained from step 1 and step 2.

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